Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Probable alpha-glucosidase AglA (Maltase) (Glucoinvertase) (Glucosidosucrase) (Maltase-glucoamylase) (Lysosomal alpha-glucosidase) (Acid maltase)

Gene

aglA

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciMTBRV:RV2471-MONOMER.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Submitted name:
Probable alpha-glucosidase AglA (Maltase) (Glucoinvertase) (Glucosidosucrase) (Maltase-glucoamylase) (Lysosomal alpha-glucosidase) (Acid maltase)Imported
Gene namesi
Name:aglAImported
Ordered Locus Names:Rv2471Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: MTBBASE
  • cytosol Source: MTBBASE
  • plasma membrane Source: MTBBASE
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO53198.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv2471.

Structurei

3D structure databases

ProteinModelPortaliO53198.
SMRiO53198. Positions 31-539.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 424386AamyInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105CG3. Bacteria.
COG0366. LUCA.
HOGENOMiHOG000220640.
KOiK01187.
OMAiESTNMYD.
OrthoDBiEOG6RVFV2.
PhylomeDBiO53198.

Family and domain databases

Gene3Di3.20.20.80. 2 hits.
InterProiIPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 2 hits.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

O53198-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQHQRPDPM GPGSPRASAR RPEPDPMGEP WWSRAVFYQV YPRSFADSNG
60 70 80 90 100
DGVGDLDGLA SRLDHLQQLG VDAIWINPVT VSPMADHGYD VADPRDIDPL
110 120 130 140 150
FGGMPAFERL VAAAHRQGIK VTMDVVPNHT SSAHPWFQAA LADLPGSPAR
160 170 180 190 200
DRYFFRDGRG PDGSLPPNNW ESVFGGPAWT RVREPDGNPG QWYLHLFDTE
210 220 230 240 250
QPDLNWDNPE ILDDFEKTLR FWLDRGVDGF RIDVAHGMAK PPGLPDSPDL
260 270 280 290 300
GIEVLHHRDD DPRFNHPNVH AIHRDIRTVI DEYPGAVTVG EVWVHDNARW
310 320 330 340 350
AEYLRPDELH LGFNFRLART EFDAAEIRDA VANSLAAAAL QNATPTWTLA
360 370 380 390 400
NHDVGREVSR YGGGEIGLRR AKAMAVVMLA LPGVVFLYNG QELGLPDVDL
410 420 430 440 450
PDEVLQDPTW ERSGRTERGR DGCRVPIPWS GNIPPFGFST CPDTWLPMPP
460 470 480 490 500
EWAALTAEKQ RADAGSTLSF FRLALRLRRE RNEFDGDVDW LAAPDDALIF
510 520 530 540
RRHGGGLVCA LNAAERPLAL PAGEPILASA PLTDATLPPN AAAWLV
Length:546
Mass (Da):60,444
Last modified:June 1, 1998 - v1
Checksum:i5CC602C3F4C587F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP45265.1.
RefSeqiNP_216987.1. NC_000962.3.
WP_003899336.1. NC_000962.3.

Genome annotation databases

EnsemblBacteriaiCCP45265; CCP45265; Rv2471.
GeneIDi887393.
KEGGimtu:Rv2471.
mtv:RVBD_2471.
PATRICi18154097. VBIMycTub87468_2770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP45265.1.
RefSeqiNP_216987.1. NC_000962.3.
WP_003899336.1. NC_000962.3.

3D structure databases

ProteinModelPortaliO53198.
SMRiO53198. Positions 31-539.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv2471.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Proteomic databases

PaxDbiO53198.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCP45265; CCP45265; Rv2471.
GeneIDi887393.
KEGGimtu:Rv2471.
mtv:RVBD_2471.
PATRICi18154097. VBIMycTub87468_2770.

Phylogenomic databases

eggNOGiENOG4105CG3. Bacteria.
COG0366. LUCA.
HOGENOMiHOG000220640.
KOiK01187.
OMAiESTNMYD.
OrthoDBiEOG6RVFV2.
PhylomeDBiO53198.

Enzyme and pathway databases

BioCyciMTBRV:RV2471-MONOMER.

Family and domain databases

Gene3Di3.20.20.80. 2 hits.
InterProiIPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 2 hits.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiO53198_MYCTU
AccessioniPrimary (citable) accession number: O53198
Secondary accession number(s): F2GHJ8, I6Y0T6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: July 6, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.