O53163 (ECH12_MYCTU) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 72.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable enoyl-CoA hydratase echA12 EC=4.2.1.17 | ||||||||
| Gene names |
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| Organism | Mycobacterium tuberculosis | ||||||||
| Taxonomic identifier | 1773 [NCBI] | ||||||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex |
Protein attributes
| Sequence length | 285 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Could possibly oxidize fatty acids using specific components By similarity. |
| Catalytic activity | (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. |
| Sequence similarities | Belongs to the enoyl-CoA hydratase/isomerase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Fatty acid metabolism Lipid metabolism |
| Molecular function | Lyase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | fatty acid metabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | plasma membrane Inferred from direct assay. Source: MTBBASE |
| Molecular function | enoyl-CoA hydratase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 285 | 285 | Probable enoyl-CoA hydratase echA12 | PRO_0000109341 | |||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BX842576 Genomic DNA. Translation: CAA16000.1. AE000516 Genomic DNA. Translation: AAK45783.1. |
| PIR | C70873. |
| RefSeq | NP_215988.1. NC_000962.2. NP_335969.1. NC_002755.2. |
3D structure databases | |
| ProteinModelPortal | O53163. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBMYCT00000001564; EBMYCP00000001564; EBMYCG00000001564. EBMYCT00000069161; EBMYCP00000067220; EBMYCG00000069156. |
| GeneID | 886547. 924454. |
| GenomeReviews | Gene locus MT1518 in contig AE000516_GR. Gene locus Rv1472 in contig AL123456_GR. |
| KEGG | mtc:MT1518. mtu:Rv1472. |
| PATRIC | 18125104. VBIMycTub22151_1667. |
| TIGR | MT1518. |
Organism-specific databases | |
| TubercuList | Rv1472. |
Phylogenomic databases | |
| GeneTree | EBGT00050000015506. |
| HOGENOM | HBG748731. |
| OMA | LEGHMQA. |
| PhylomeDB | O53163. |
| ProtClustDB | PRK05864. |
Family and domain databases | |
| InterPro | IPR001753. Crotonase_core. IPR018376. Enoyl-CoA_hyd/isom_CS. [Graphical view] |
| KO | K01692. |
| Pfam | PF00378. ECH. 1 hit. [Graphical view] |
| PROSITE | PS00166. ENOYL_COA_HYDRATASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ECH12_MYCTU | ||||||||
| Accession | Primary (citable) accession number: O53163 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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