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Protein

Carbamate kinase

Gene

arcC

Organism
Lactobacillus sakei
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + NH3 + CO2 = ADP + carbamoyl phosphate.

Pathwayi: carbamoyl phosphate degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from carbamoyl phosphate.
Proteins known to be involved in this subpathway in this organism are:
  1. Carbamate kinase (arcC)
This subpathway is part of the pathway carbamoyl phosphate degradation, which is itself part of Metabolic intermediate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from carbamoyl phosphate, the pathway carbamoyl phosphate degradation and in Metabolic intermediate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Arginine metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00996; UER00366.

Names & Taxonomyi

Protein namesi
Recommended name:
Carbamate kinase (EC:2.7.2.2)
Gene namesi
Name:arcC
OrganismiLactobacillus sakei
Taxonomic identifieri1599 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314Carbamate kinasePRO_0000185127Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi314315.LSA0372.

Structurei

3D structure databases

ProteinModelPortaliO53090.
SMRiO53090. Positions 4-312.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the carbamate kinase family.Curated

Phylogenomic databases

eggNOGiENOG4105C5B. Bacteria.
COG0549. LUCA.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
InterProiIPR001048. Asp/Glu/Uridylate_kinase.
IPR003964. Carb_kinase.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000723. Carbamate_kin. 1 hit.
PRINTSiPR01469. CARBMTKINASE.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00746. arcC. 1 hit.

Sequencei

Sequence statusi: Complete.

O53090-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKRKIVVAL GGNAILSTDA SANAQIKAVK ETVKQLVAFV KQGDQLIISH
60 70 80 90 100
GNGPQVGNLL IQQAASDSEK TPAMPLDTVG AMSQGEIGYW MQNAFNEVLA
110 120 130 140 150
EEGLALDVAT IVTQTIVDAK DEAFQNPTKP IGPFYSEAEA KKQQSINPEA
160 170 180 190 200
HFVEDAGRGW RRVVPSPRPI GIQEAPVIQK LVEGNVITIS AGGGGVPVAK
210 220 230 240 250
EGNKLRGVEA VIDKDFASEK LAELVGADML IILTAVDNVY VNFNKPDQKK
260 270 280 290 300
LTNVSVAELE DYIKDDQFAK GSMLPKIQTA IEYVNNRPDS KAIITSLDNV
310
KNLLAHDAGT IITK
Length:314
Mass (Da):33,652
Last modified:June 1, 1998 - v1
Checksum:i7B717D56473A7FD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001330 Genomic DNA. Translation: CAA04684.1.
PIRiT46743.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001330 Genomic DNA. Translation: CAA04684.1.
PIRiT46743.

3D structure databases

ProteinModelPortaliO53090.
SMRiO53090. Positions 4-312.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi314315.LSA0372.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105C5B. Bacteria.
COG0549. LUCA.

Enzyme and pathway databases

UniPathwayiUPA00996; UER00366.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
InterProiIPR001048. Asp/Glu/Uridylate_kinase.
IPR003964. Carb_kinase.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000723. Carbamate_kin. 1 hit.
PRINTSiPR01469. CARBMTKINASE.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00746. arcC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Structural and functional analysis of the gene cluster encoding the enzymes of the arginine deiminase pathway of Lactobacillus sakei."
    Zuniga M., Champomier-Verges M.-C., Zagorec M., Perez-Martinez G.
    J. Bacteriol. 180:4154-4159(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiARCC_LACSK
AccessioniPrimary (citable) accession number: O53090
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: November 11, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.