Reviewed, UniProtKB/Swiss-Prot O53079 (CILA_LEUMC)

Names and origin

Protein names

Recommended name:
    Citrate lyase alpha chain
      Short name=Citrase alpha chain
    EC=4.1.3.6
Alternative name(s):
    Citrate (pro-3S)-lyase alpha chain
    Citrate CoA-transferase subunit
    EC=2.8.3.10

Gene names

Name:

citF

Organism

Leuconostoc mesenteroides subsp. cremoris

Taxonomic identifier

33965 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Leuconostoc

Protein attributes

Sequence length	512 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Represents a citrate:acetyl-ACP transferase By similarity.
Catalytic activity	Citrate = acetate + oxaloacetate. Acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.
Subunit structure	Oligomer with a subunit composition of (alpha,beta, gamma)6 By similarity.
Subcellular location	Cytoplasm.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Lyase Transferase
Gene Ontology (GO)
Biological process	acetyl-CoA metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	citrate lyase complex Inferred from electronic annotation. Source: InterPro
Molecular function	citrate (pro-3S)-lyase activity Inferred from electronic annotation. Source: EC citrate CoA-transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 512	512	Citrate lyase alpha chain		PRO_0000089755

Sequences

	Sequence		Length	Mass (Da)
	O53079-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 6617CBB96B5A73C0	FASTA	512	55,068
	10 20 30 40 50 60 MKNKVNIDVP DAILEQLDDS VFESTNYGNP EIQRVGPKVR ATTGESKVQS SIDDVLSNTL 70 80 90 100 110 120 KDGMTISFHH HFREGDFVFN KVMRKIIDMG YQNLTLAPSS LTNVMNDIVI EAIKKGVVTN 130 140 150 160 170 180 ITSSGMRGTL GDAVSHGILK NPVIFRSHGA RARAIESGEI KIDVAFLGVP NSDEMGNANG 190 200 210 220 230 240 MNGDAAFGSL GYALIDAQYA DKLVLITDTI MPYPNTPASI KQTQVDYVVK VDKVGDPDKI 250 260 270 280 290 300 GSGATRFTKD PKELKIAKTV NDVIVNSKYF KNDFSFQTGS GGAALAVTRF LREAMMAQNI 310 320 330 340 350 360 MASFALGGIT KPTVDLLNEG LVNRVMDVQD FDKGAASSMK LSPNQQEIDA SWYADPANKG 370 380 390 400 410 420 AMVDKLDVAI LSALEVDTNF NVNVMSGSDG VIRGAIGGHQ DAATAKLTII SVPLVRGRIA 430 440 450 460 470 480 TIVPKVNTVI TPGDSIDVVV TEVGIAINPK RTDLVEQLKQ VPGLPIYSIE ELQQKAEKIV 490 500 510 GQPAPLKFTD RVVAVAEYRD GSVIDIIKEV AD

References

[1]

"Purification of Leuconostoc mesenteroides citrate lyase and cloning and characterization of the citCDEFG gene cluster." Bekal S., van Beeumen J., Samyn B., Garmyn D., Henini S., Divies C., Prevost H. J. Bacteriol. 180:647-654(1998) [PubMed: 9457870] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 195.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y10621 Genomic DNA. Translation: CAA71633.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.8.3.10. 190084. 4.1.3.6. 190084.
Family and domain databases
InterPro	IPR006472. Citrate_lyase_asu. [Graphical view]
Pfam	PF04223. CitF. 1 hit. [Graphical view]
PIRSF	PIRSF009451. Citrt_lyas_alpha. 1 hit.
TIGRFAMs	TIGR01584. citF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CILA_LEUMC

Accession

Primary (citable) accession number: O53079

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	June 1, 1998
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)