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Protein

Lipoprotein YfjS

Gene

yfjS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Does not induce degP when overexpressed unless it is mutated to resemble YafY.1 Publication

Enzyme and pathway databases

BioCyciEcoCyc:G7371-MONOMER.
ECOL316407:JW5921-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipoprotein YfjS
Gene namesi
Name:yfjS
Ordered Locus Names:b2636, JW5921
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13205. yfjS.

Subcellular locationi

  • Cell inner membrane 1 Publication; Lipid-anchor 1 Publication

GO - Cellular componenti

  • plasma membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi60 – 61GF → DY: 3-fold improved induction of degP upon overexpression; when associated with Q-136. 1 Publication2
Mutagenesisi136R → Q: 3-fold improved induction of degP upon overexpression; when associated with 60-D-Y-61. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20PROSITE-ProRule annotationAdd BLAST20
ChainiPRO_000001804721 – 147Lipoprotein YfjSAdd BLAST127

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi21N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi21S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiO52982.
PRIDEiO52982.

Interactioni

Protein-protein interaction databases

BioGridi4260628. 8 interactors.
STRINGi511145.b2636.

Structurei

3D structure databases

ProteinModelPortaliO52982.
SMRiO52982.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To E.coli YafY.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000028675.
OMAiSHKSDIA.

Family and domain databases

PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O52982-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRKTLPLLA LVATSLFLSA CDDRSDDLKA ISKFKDLTPP RFSDVVSRQD
60 70 80 90 100
DVSEEWSQVG FSSGLTLQVL RTRESPDGCE GGSYYYLVDM EEKTVQPLMN
110 120 130 140
ALCIADNIKL EYHEVTDPYT KEKYFEYSHD GKLMGRLLIP SNPDNRE
Length:147
Mass (Da):16,735
Last modified:December 15, 1998 - v2
Checksum:i294131E411B78C7A
GO

Sequence cautioni

The sequence AAA79804 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36840 Genomic DNA. Translation: AAA79804.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75684.2.
AP009048 Genomic DNA. Translation: BAE76771.1.
PIRiF65042.
RefSeqiNP_417124.4. NC_000913.3.
WP_000824222.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75684; AAC75684; b2636.
BAE76771; BAE76771; BAE76771.
GeneIDi945668.
KEGGiecj:JW5921.
eco:b2636.
PATRICi32120663. VBIEscCol129921_2730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36840 Genomic DNA. Translation: AAA79804.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75684.2.
AP009048 Genomic DNA. Translation: BAE76771.1.
PIRiF65042.
RefSeqiNP_417124.4. NC_000913.3.
WP_000824222.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliO52982.
SMRiO52982.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260628. 8 interactors.
STRINGi511145.b2636.

Proteomic databases

PaxDbiO52982.
PRIDEiO52982.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75684; AAC75684; b2636.
BAE76771; BAE76771; BAE76771.
GeneIDi945668.
KEGGiecj:JW5921.
eco:b2636.
PATRICi32120663. VBIEscCol129921_2730.

Organism-specific databases

EcoGeneiEG13205. yfjS.

Phylogenomic databases

HOGENOMiHOG000028675.
OMAiSHKSDIA.

Enzyme and pathway databases

BioCyciEcoCyc:G7371-MONOMER.
ECOL316407:JW5921-MONOMER.

Miscellaneous databases

PROiO52982.

Family and domain databases

PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFJS_ECOLI
AccessioniPrimary (citable) accession number: O52982
Secondary accession number(s): Q2MAD5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 15, 1998
Last modified: November 2, 2016
This is version 95 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.