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Protein

RNA polymerase sigma factor RpoD

Gene

rpoD

Organism
Campylobacter jejuni
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.SAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi580 – 599H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor RpoDUniRule annotation
Alternative name(s):
Sigma-70UniRule annotation
Gene namesi
Name:rpoDUniRule annotationImported
OrganismiCampylobacter jejuniImported
Taxonomic identifieri197 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Interacts transiently with the RNA polymerase catalytic core.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO52921.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini409 – 422RNA_pol_sigma70InterPro annotationAdd BLAST14
Domaini579 – 605RNA_pol_sigma70InterPro annotationAdd BLAST27

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni385 – 455Sigma-70 factor domain-2UniRule annotationAdd BLAST71
Regioni464 – 540Sigma-70 factor domain-3UniRule annotationAdd BLAST77

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi409 – 412Interaction with polymerase core subunit RpoCUniRule annotation4

Phylogenomic databases

eggNOGiENOG4105DG1. Bacteria.
COG0568. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
HAMAPiMF_00963. Sigma70_RpoD_SigA. 1 hit.
InterProiView protein in InterPro
IPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR009042. RNA_pol_sigma70_r1_2.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR012760. RNA_pol_sigma_RpoD_C.
IPR028630. Sigma70_RpoD.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00140. Sigma70_r1_2. 1 hit.
PF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02393. RpoD_Cterm. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiView protein in PROSITE
PS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O52921-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAKTQEAEL EELFQENAKD YITYEKLVKY LTKQPSASTA KKVQALMKKH
60 70 80 90 100
KVQLFSAAEI GQMKNIEDAK RLQEEKQKLQ DTSLENEFDL ANENDLLEWS
110 120 130 140 150
RSDSPVRMYL REMGQIALLN KDEEIEISKK IELGEDIIID AFCSVPYLID
160 170 180 190 200
FILDYKEPLI NRERRVKELF KSFDDEEKSD DKLDELDIDE DEENETELES
210 220 230 240 250
DEENTKKNSK KEDERTLKVI EKFKALEKAK KDWLKTSKDK ESGDELLDKL
260 270 280 290 300
SIAFKKNILK EKLMDLGPTS KLISEIVKSM ETALKSDEEF DKELKRLEYR
310 320 330 340 350
LPMFSDELKK RHADILKDIT KLSKEEITER ALETTMVSTY MEIKKLFQTK
360 370 380 390 400
EASEKSFDLE KSRLKEILEQ IKRGKKISDE AKGRMAKSNL RLVVSIAKRY
410 420 430 440 450
TNRGLPFLDL IQEGNIGLMK AVDKFEYKRG YKFSTYATWW IRQAISRAIA
460 470 480 490 500
DQARTIRIPI HMIETINQIN KIIREHLQKD GKEPDVSVIA KEVGLSVDKV
510 520 530 540 550
KQVIKITKEP ISLEAPIGNE DDGKFGDFVE DRNSLSPMDH ILKDDLKEQI
560 570 580 590 600
DEVLDQLNDR EKAVIRMRFG LMDDESDRTL EEIGKELNVT RERVRQIESS
610 620
AIKKLKHPKV GRKLKNYIEG WK
Length:622
Mass (Da):72,562
Last modified:June 1, 1998 - v1
Checksum:i365E7AE8D85C7AE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002379 Genomic DNA. Translation: CAA05353.1.

Similar proteinsi

Entry informationi

Entry nameiO52921_CAMJU
AccessioniPrimary (citable) accession number: O52921
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: September 27, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation