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Protein

Flagellar biosynthesis protein FlhF

Gene

flhF

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi289 – 296GTPBy similarity8
Nucleotide bindingi367 – 371GTPBy similarity5
Nucleotide bindingi426 – 429GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-62-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar biosynthesis protein FlhF
Alternative name(s):
Flagella-associated GTP-binding protein
Gene namesi
Name:flhF
Ordered Locus Names:Cj0064c
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001012221 – 484Flagellar biosynthesis protein FlhFAdd BLAST484

Proteomic databases

PaxDbiO52908.
PRIDEiO52908.

Interactioni

Protein-protein interaction databases

IntActiO52908. 5 interactors.
MINTiMINT-6483871.
STRINGi192222.Cj0064c.

Structurei

3D structure databases

ProteinModelPortaliO52908.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GTP-binding SRP family.Curated

Phylogenomic databases

eggNOGiENOG4105FZW. Bacteria.
COG1419. LUCA.
HOGENOMiHOG000254735.
KOiK02404.
OMAiVNIPQEF.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR020006. FlhF.
IPR027417. P-loop_NTPase.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PANTHERiPTHR11564:SF3. PTHR11564:SF3. 1 hit.
PfamiPF00448. SRP54. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03499. FlhF. 1 hit.

Sequencei

Sequence statusi: Complete.

O52908-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQLIHTFTV EDTEQIIPKV KEDYGDKALI ITNKQIRPKT LNRSALYEVM
60 70 80 90 100
VAIEESDYEE HLKKQGKSLP AKKSSPKPSS TSLAEEKIRS QIPQEDEDVV
110 120 130 140 150
LDFSNTRLNT NLNTVKNNDL AKKTYQDFPQ NKINPHQNKT LGFDDFKEKL
160 170 180 190 200
SEVSNEISKV TNTPLENYTP NPNYNKKIEN FEKQFEKQIN KLNDKIDLLA
210 220 230 240 250
DMMWDDKAEA RKNLMIPPEF ASIYKQAKES GMLENHLEAI MKATIENMPA
260 270 280 290 300
AMKTNKDAVQ RYFHSLLRNI LPCRVESDIK KQKIMMLVGP TGVGKTTTLA
310 320 330 340 350
KLAFRYAYGD KRYKTGIITL DTYRIGAVEQ LFQYAKMMKL PIIDSIEPKD
360 370 380 390 400
LDEAIKSLNN CEVILVDTIG NSQYDQSKLA KTKEFLMHSN AEIDVNLVVS
410 420 430 440 450
ANTKHEDLME IYKNFSFLNI DTLIITKFDE TKVFGNIFSL VYETNIPLSF
460 470 480
FSIGQEVPDD LEVANSDFLV HCILEGFNKG KNNE
Length:484
Mass (Da):55,356
Last modified:December 1, 2000 - v2
Checksum:i50BB174F3BEBB357
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti374Y → T in CAA04334 (Ref. 2) Curated1
Sequence conflicti377S → I in CAA04334 (Ref. 2) Curated1
Sequence conflicti472 – 484CILEG…GKNNE → WYFRRV in CAA04334 (Ref. 2) CuratedAdd BLAST13

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL34238.1.
AJ000857 Genomic DNA. Translation: CAA04334.1.
PIRiD81422.
RefSeqiWP_002851941.1. NC_002163.1.
YP_002343528.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL34238; CAL34238; Cj0064c.
GeneIDi904464.
KEGGicje:Cj0064c.
PATRICi20057057. VBICamJej33762_0063.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL34238.1.
AJ000857 Genomic DNA. Translation: CAA04334.1.
PIRiD81422.
RefSeqiWP_002851941.1. NC_002163.1.
YP_002343528.1. NC_002163.1.

3D structure databases

ProteinModelPortaliO52908.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO52908. 5 interactors.
MINTiMINT-6483871.
STRINGi192222.Cj0064c.

Proteomic databases

PaxDbiO52908.
PRIDEiO52908.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL34238; CAL34238; Cj0064c.
GeneIDi904464.
KEGGicje:Cj0064c.
PATRICi20057057. VBICamJej33762_0063.

Phylogenomic databases

eggNOGiENOG4105FZW. Bacteria.
COG1419. LUCA.
HOGENOMiHOG000254735.
KOiK02404.
OMAiVNIPQEF.

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-62-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR020006. FlhF.
IPR027417. P-loop_NTPase.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PANTHERiPTHR11564:SF3. PTHR11564:SF3. 1 hit.
PfamiPF00448. SRP54. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03499. FlhF. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFLHF_CAMJE
AccessioniPrimary (citable) accession number: O52908
Secondary accession number(s): Q0PC69, Q9PJ55
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 1, 2000
Last modified: November 2, 2016
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.