SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O52847

- BGAL_BACMD

UniProt

O52847 - BGAL_BACMD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Beta-galactosidase
Gene
bgaM, BMD_2126
Organism
Bacillus megaterium (strain DSM 319)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei481 – 4811Proton donor By similarity
Active sitei547 – 5471Nucleophile By similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciBMEG592022:GIVX-2126-MONOMER.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase (EC:3.2.1.23)
Short name:
Beta-gal
Alternative name(s):
Lactase
Gene namesi
Name:bgaM
Ordered Locus Names:BMD_2126
OrganismiBacillus megaterium (strain DSM 319)
Taxonomic identifieri592022 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000002365: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10341034Beta-galactosidase
PRO_0000057659Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO52847.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000252444.
KOiK01190.
OMAiRTIERDK.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O52847-1 [UniParc]FASTAAdd to Basket

« Hide

MLKTGKKFHY TAPANGYPEW NNNPEIFQLN RSKAHALLMP YQTVEEALKN     50
DRKSSVYYQS LNGSWYFHFA ENADGRVKNF FAPEFSYEKW DSISVPSHWQ 100
LQGYDYPQYT NVTYPWVENE ELEPPFAPTK YNPVGQYVRT FTPKSEWKDQ 150
PVYISFQGVE SAFYVWINGE FVGYSEDSFT PAEFDITSYL QEGENTIAVE 200
VYRWSDASWL EDQDFWRMSG IFRDVYLYST PQVHIYDFSV RSSLDNNYED 250
GELSVSADIL NYFEHDTQDL TFEVMLYDAN AQEVLQAPLQ TNLSVSDQRT 300
VSLRTHIKSP AKWSAESPNL YTLVLSLKNA AGSIIETESC KVGFRTFEIK 350
NGLMTINGKR IVLRGVNRHE FDSVKGRAGI TREDMIHDIL LMKQHNINAV 400
RTSHYPNDSV WYELCNEYGL YVIDETNLET HGTWTYLQEG EQKAVPGSKP 450
EWKENVLDRC RSMYERDKNH PSIIIWSLGN ESFGGENFQH MYTFFKEKDS 500
TRLVHYEGIF HHRDYDASDI ESTMYVKPAD VERYALMNPK KPYILCEYSH 550
AMGNSCGNLY KYWELFDQYP ILQGGFIWDW KDQALQATAE DGTSYLAYGG 600
DFGDTPNDGN FCGNGLIFAD GTASPKIAEV KKCYQPVKWT AVDPAKGKFA 650
VQNKHLFTNL NAYDFVWTVE KNGELVEKHA SLLNVAPDGT DELTLSYPLY 700
EQENETDEFV LTLSLRLSKD TAWASAGYEV AYEQFVLPAK AAMPSVKAAH 750
PALTVDQNEQ TLTVTGTNFT AIFDKRKGQF ISYNYERTEL LASGFRPNFW 800
RAVTDNDLGN KLHERCQTWR QASLEQHVKK VTVQPQVDFV IISVELALDN 850
SLASCYVTYT LYNDGEMKIE QSLAPSETMP EIPEIGMLFT MNAAFDSLTW 900
YGRGPHENYW DRKTGAKLAL HKGSVKEQVT PYLRPQECGN KTDVRWATIT 950
NDQGRGFLIK GLPTVELNAL PYSPFELEAY DHFYKLPASD SVTVRVNYKQ 1000
MGVGGDDSWQ AKTHPNYTLY ANRSYTNTFT LKPL 1034
Length:1,034
Mass (Da):118,674
Last modified:June 1, 1998 - v1
Checksum:i38644C9A649415E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ000733 Genomic DNA. Translation: CAA04267.1.
CP001982 Genomic DNA. Translation: ADF38979.1.
PIRiT30574.
RefSeqiWP_013082993.1. NC_014103.1.
YP_003597329.1. NC_014103.1.

Genome annotation databases

EnsemblBacteriaiADF38979; ADF38979; BMD_2126.
GeneIDi9117517.
KEGGibmd:BMD_2126.
PATRICi37254301. VBIBacMeg104484_2076.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ000733 Genomic DNA. Translation: CAA04267.1 .
CP001982 Genomic DNA. Translation: ADF38979.1 .
PIRi T30574.
RefSeqi WP_013082993.1. NC_014103.1.
YP_003597329.1. NC_014103.1.

3D structure databases

ProteinModelPortali O52847.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADF38979 ; ADF38979 ; BMD_2126 .
GeneIDi 9117517.
KEGGi bmd:BMD_2126.
PATRICi 37254301. VBIBacMeg104484_2076.

Phylogenomic databases

HOGENOMi HOG000252444.
KOi K01190.
OMAi RTIERDK.

Enzyme and pathway databases

BioCyci BMEG592022:GIVX-2126-MONOMER.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProi IPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view ]
PRINTSi PR00132. GLHYDRLASE2.
SMARTi SM01038. Bgal_small_N. 1 hit.
[Graphical view ]
SUPFAMi SSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEi PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Strey J.
    Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure."
    Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 319.

Entry informationi

Entry nameiBGAL_BACMD
AccessioniPrimary (citable) accession number: O52847
Secondary accession number(s): D5DFH9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi