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Protein

Beta-galactosidase

Gene

bgaM

Organism
Bacillus megaterium (strain DSM 319)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei481Proton donorBy similarity1
Active sitei547NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Enzyme and pathway databases

BioCyciBMEG592022:G1GHR-2120-MONOMER
BRENDAi3.2.1.23 656

Protein family/group databases

CAZyiGH2 Glycoside Hydrolase Family 2

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase (EC:3.2.1.23)
Short name:
Beta-gal
Alternative name(s):
Lactase
Gene namesi
Name:bgaM
Ordered Locus Names:BMD_2126
OrganismiBacillus megaterium (strain DSM 319)
Taxonomic identifieri592022 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000002365 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000576591 – 1034Beta-galactosidaseAdd BLAST1034

Proteomic databases

PRIDEiO52847

Structurei

3D structure databases

ProteinModelPortaliO52847
SMRiO52847
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.Curated

Phylogenomic databases

HOGENOMiHOG000252444
KOiK01190
OMAiDQDMFRL
OrthoDBiPOG091H07QB

Family and domain databases

Gene3Di2.60.120.260, 1 hit
2.60.40.10, 2 hits
2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR004199 B-gal_small/dom_5
IPR036156 Beta-gal/glucu_dom_sf
IPR011013 Gal_mutarotase_sf_dom
IPR008979 Galactose-bd-like_sf
IPR014718 GH-type_carb-bd
IPR006101 Glyco_hydro_2
IPR023232 Glyco_hydro_2_AS
IPR006103 Glyco_hydro_2_cat
IPR023230 Glyco_hydro_2_CS
IPR006102 Glyco_hydro_2_Ig-like
IPR006104 Glyco_hydro_2_N
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR032312 LacZ_4
PfamiView protein in Pfam
PF02929 Bgal_small_N, 1 hit
PF16353 DUF4981, 1 hit
PF00703 Glyco_hydro_2, 1 hit
PF02836 Glyco_hydro_2_C, 1 hit
PF02837 Glyco_hydro_2_N, 1 hit
PRINTSiPR00132 GLHYDRLASE2
SMARTiView protein in SMART
SM01038 Bgal_small_N, 1 hit
SUPFAMiSSF49303 SSF49303, 2 hits
SSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 1 hit
PROSITEiView protein in PROSITE
PS00719 GLYCOSYL_HYDROL_F2_1, 1 hit
PS00608 GLYCOSYL_HYDROL_F2_2, 1 hit

Sequencei

Sequence statusi: Complete.

O52847-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKTGKKFHY TAPANGYPEW NNNPEIFQLN RSKAHALLMP YQTVEEALKN
60 70 80 90 100
DRKSSVYYQS LNGSWYFHFA ENADGRVKNF FAPEFSYEKW DSISVPSHWQ
110 120 130 140 150
LQGYDYPQYT NVTYPWVENE ELEPPFAPTK YNPVGQYVRT FTPKSEWKDQ
160 170 180 190 200
PVYISFQGVE SAFYVWINGE FVGYSEDSFT PAEFDITSYL QEGENTIAVE
210 220 230 240 250
VYRWSDASWL EDQDFWRMSG IFRDVYLYST PQVHIYDFSV RSSLDNNYED
260 270 280 290 300
GELSVSADIL NYFEHDTQDL TFEVMLYDAN AQEVLQAPLQ TNLSVSDQRT
310 320 330 340 350
VSLRTHIKSP AKWSAESPNL YTLVLSLKNA AGSIIETESC KVGFRTFEIK
360 370 380 390 400
NGLMTINGKR IVLRGVNRHE FDSVKGRAGI TREDMIHDIL LMKQHNINAV
410 420 430 440 450
RTSHYPNDSV WYELCNEYGL YVIDETNLET HGTWTYLQEG EQKAVPGSKP
460 470 480 490 500
EWKENVLDRC RSMYERDKNH PSIIIWSLGN ESFGGENFQH MYTFFKEKDS
510 520 530 540 550
TRLVHYEGIF HHRDYDASDI ESTMYVKPAD VERYALMNPK KPYILCEYSH
560 570 580 590 600
AMGNSCGNLY KYWELFDQYP ILQGGFIWDW KDQALQATAE DGTSYLAYGG
610 620 630 640 650
DFGDTPNDGN FCGNGLIFAD GTASPKIAEV KKCYQPVKWT AVDPAKGKFA
660 670 680 690 700
VQNKHLFTNL NAYDFVWTVE KNGELVEKHA SLLNVAPDGT DELTLSYPLY
710 720 730 740 750
EQENETDEFV LTLSLRLSKD TAWASAGYEV AYEQFVLPAK AAMPSVKAAH
760 770 780 790 800
PALTVDQNEQ TLTVTGTNFT AIFDKRKGQF ISYNYERTEL LASGFRPNFW
810 820 830 840 850
RAVTDNDLGN KLHERCQTWR QASLEQHVKK VTVQPQVDFV IISVELALDN
860 870 880 890 900
SLASCYVTYT LYNDGEMKIE QSLAPSETMP EIPEIGMLFT MNAAFDSLTW
910 920 930 940 950
YGRGPHENYW DRKTGAKLAL HKGSVKEQVT PYLRPQECGN KTDVRWATIT
960 970 980 990 1000
NDQGRGFLIK GLPTVELNAL PYSPFELEAY DHFYKLPASD SVTVRVNYKQ
1010 1020 1030
MGVGGDDSWQ AKTHPNYTLY ANRSYTNTFT LKPL
Length:1,034
Mass (Da):118,674
Last modified:June 1, 1998 - v1
Checksum:i38644C9A649415E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ000733 Genomic DNA Translation: CAA04267.1
CP001982 Genomic DNA Translation: ADF38979.1
PIRiT30574
RefSeqiWP_013082993.1, NC_014103.1

Genome annotation databases

EnsemblBacteriaiADF38979; ADF38979; BMD_2126
KEGGibmd:BMD_2126
PATRICifig|592022.4.peg.2076

Similar proteinsi

Entry informationi

Entry nameiBGAL_BACMD
AccessioniPrimary (citable) accession number: O52847
Secondary accession number(s): D5DFH9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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