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Protein
Submitted name:

Xylanase U

Gene

xynU

Organism
Clostridium thermocellum (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi255CalciumCombined sources1
Metal bindingi257CalciumCombined sources1
Metal bindingi277Calcium; via carbonyl oxygenCombined sources1
Metal bindingi369CalciumCombined sources1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradationImported

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BRENDAi3.2.1.8. 1530.

Protein family/group databases

CAZyiCBM6. Carbohydrate-Binding Module Family 6.
GH11. Glycoside Hydrolase Family 11.
mycoCLAPiXYN11U_CLOTH.

Names & Taxonomyi

Protein namesi
Submitted name:
Xylanase UImported
Gene namesi
Name:xynUImported
OrganismiClostridium thermocellum (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri1515 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500415890229 – 683Sequence analysisAdd BLAST655

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_2972.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GMMX-ray2.00A248-380[»]
1UXXX-ray1.60X248-380[»]
ProteinModelPortaliO52780.
SMRiO52780.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO52780.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 225GH11 (glycosyl hydrolase family 11)InterPro annotationAdd BLAST195
Domaini252 – 374CBM6 (carbohydrate binding type-6)InterPro annotationAdd BLAST123
Domaini388 – 456DockerinInterPro annotationAdd BLAST69
Domaini480 – 658NodB homologyInterPro annotationAdd BLAST179

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4107T94. Bacteria.
COG0726. LUCA.
COG5498. LUCA.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.120.180. 1 hit.
2.60.120.260. 1 hit.
3.20.20.370. 1 hit.
InterProiIPR006584. Cellulose-bd_IV.
IPR005084. CMB_fam6.
IPR013320. ConA-like_dom.
IPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR008979. Galactose-bd-like.
IPR013319. GH11/12.
IPR018208. GH11_AS_1.
IPR033119. GH11_AS_2.
IPR033123. GH11_dom.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR001137. Glyco_hydro_11.
IPR002509. NODB_dom.
[Graphical view]
PfamiPF03422. CBM_6. 1 hit.
PF00404. Dockerin_1. 2 hits.
PF00457. Glyco_hydro_11. 1 hit.
PF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
PRINTSiPR00911. GLHYDRLASE11.
SMARTiSM00606. CBD_IV. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF49899. SSF49899. 1 hit.
SSF63446. SSF63446. 1 hit.
SSF88713. SSF88713. 1 hit.
PROSITEiPS51175. CBM6. 1 hit.
PS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
PS00018. EF_HAND_1. 2 hits.
PS00776. GH11_1. 1 hit.
PS00777. GH11_2. 1 hit.
PS51761. GH11_3. 1 hit.
PS51677. NODB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O52780-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQKLLVTFL ILITFTVSLT LFPVNVRADV VITSNQTGTH GGYNFEYWKD
60 70 80 90 100
TGNGTMVLKD GGAFSCEWSN INNILFRKGF KYDETKRHDQ LGYITVTYSC
110 120 130 140 150
NYQPNGNSYL GVYGWTSNPL VEYYIIESWG TWRPPGATPK GTITVDGGTY
160 170 180 190 200
EIYETTRVNQ PSIKGTATFQ QYWSVRTSKR TSGTISVTEH FKAWERLGMK
210 220 230 240 250
MGKMYEVALV VEGYQSSGKA DVTSMTITVG NAPSTSSPPG PTPEPTPRSA
260 270 280 290 300
FSKIESEEYN SLKSSTIQTI GTSDGGSGIG YIESGDYLVF NKINFGNGAN
310 320 330 340 350
SFKARVASGA DTPTNIQLRL GSPTGTLIGT LTVASTGGWN NYEEKSCSIT
360 370 380 390 400
NTTGQHDLYL VFSGPVNIDY FIFDSNGVNP TPTSQPQQGQ VLGDLNGDKQ
410 420 430 440 450
VNSTDYTALK RHLLNITRLS GTALANADLN GDGKVDSTDL MILHRYLLGI
460 470 480 490 500
ISSFPRSNPQ PSSNPQPSSN PQPTINPNAK LVALTFDDGP DNVLTARVLD
510 520 530 540 550
KLDKYNVKAT FMVVGQRVND STAAIIRRMV NSGHEIGNHS WSYSGMANMS
560 570 580 590 600
PDQIRKSIAD TNAVIQKYAG TTPKFFRAPN LETSPTLFNN VDLVFVGGLT
610 620 630 640 650
ANDWIPSTTA EQRAGAVING VRDGTIILLH DVQPEPHPTP EALDIIIPTL
660 670 680
KSRGYEFVTL TELFTLKGVP IDPSVKRMYN SVP
Length:683
Mass (Da):74,530
Last modified:June 1, 1998 - v1
Checksum:i714BB16E0C9820A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF047761 Genomic DNA. Translation: AAC04579.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF047761 Genomic DNA. Translation: AAC04579.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GMMX-ray2.00A248-380[»]
1UXXX-ray1.60X248-380[»]
ProteinModelPortaliO52780.
SMRiO52780.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203119.Cthe_2972.

Protein family/group databases

CAZyiCBM6. Carbohydrate-Binding Module Family 6.
GH11. Glycoside Hydrolase Family 11.
mycoCLAPiXYN11U_CLOTH.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4107T94. Bacteria.
COG0726. LUCA.
COG5498. LUCA.

Enzyme and pathway databases

BRENDAi3.2.1.8. 1530.

Miscellaneous databases

EvolutionaryTraceiO52780.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.120.180. 1 hit.
2.60.120.260. 1 hit.
3.20.20.370. 1 hit.
InterProiIPR006584. Cellulose-bd_IV.
IPR005084. CMB_fam6.
IPR013320. ConA-like_dom.
IPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR008979. Galactose-bd-like.
IPR013319. GH11/12.
IPR018208. GH11_AS_1.
IPR033119. GH11_AS_2.
IPR033123. GH11_dom.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR001137. Glyco_hydro_11.
IPR002509. NODB_dom.
[Graphical view]
PfamiPF03422. CBM_6. 1 hit.
PF00404. Dockerin_1. 2 hits.
PF00457. Glyco_hydro_11. 1 hit.
PF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
PRINTSiPR00911. GLHYDRLASE11.
SMARTiSM00606. CBD_IV. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF49899. SSF49899. 1 hit.
SSF63446. SSF63446. 1 hit.
SSF88713. SSF88713. 1 hit.
PROSITEiPS51175. CBM6. 1 hit.
PS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
PS00018. EF_HAND_1. 2 hits.
PS00776. GH11_1. 1 hit.
PS00777. GH11_2. 1 hit.
PS51761. GH11_3. 1 hit.
PS51677. NODB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO52780_CLOTM
AccessioniPrimary (citable) accession number: O52780
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: November 2, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.