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O52748 (PATS_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Heterocyst inhibition-signaling peptide
Gene names
Name:patS
Ordered Locus Names:asl2301
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length17 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. Ref.1 Ref.3 Ref.4

Subcellular location

Periplasm Probable. Note: Seems to diffuse to adjacent cells.

Developmental stage

Expressed in proheterocysts.

Ontologies

Keywords
   Cellular componentPeriplasm
   Developmental stageHeterocyst
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processheterocyst differentiation

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Peptide1 – 1717Heterocyst inhibition-signaling peptide
PRO_0000044184

Sequences

Sequence LengthMass (Da)Tools
O52748 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 192BE168476867F3

FASTA171,927
        10 
MKAIMLVNFC DERGSGR 

« Hide

References

« Hide 'large scale' references
[1]"Heterocyst pattern formation controlled by a diffusible peptide."
Yoon H.-S., Golden J.W.
Science 282:935-938(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
[2]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.
[3]"PatS and products of nitrogen fixation control heterocyst pattern."
Yoon H.S., Golden J.W.
J. Bacteriol. 183:2605-2613(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[4]"HetR homodimer is a DNA-binding protein required for heterocyst differentiation, and the DNA-binding activity is inhibited by PatS."
Huang X., Dong Y., Zhao J.
Proc. Natl. Acad. Sci. U.S.A. 101:4848-4853(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION IN INHIBITION OF DNA-BINDING OF HETR.

Web resources

Protein Spotlight

Heterocyst or not heterocyst? - Issue 23 of June 2002

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF046871 Genomic DNA. Translation: AAC03103.1.
BA000019 Genomic DNA. Translation: BAB74000.1.
PIRAF2093.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB74000; BAB74000; BAB74000.

Organism-specific databases

CMRSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry namePATS_NOSS1
AccessionPrimary (citable) accession number: O52748
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: June 1, 1998
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries