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Protein

D-xylose-proton symporter

Gene

xylT

Organism
Lactobacillus brevis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei138 – 1381MonosaccharideBy similarity
Binding sitei362 – 3621MonosaccharideBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Symport, Transport

Protein family/group databases

TCDBi2.A.1.1.41. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
D-xylose-proton symporter
Alternative name(s):
D-xylose transporter
Gene namesi
Name:xylT
OrganismiLactobacillus brevis
Taxonomic identifieri1580 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1313CytoplasmicSequence analysisAdd
BLAST
Transmembranei14 – 3421Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini35 – 4511ExtracellularSequence analysisAdd
BLAST
Transmembranei46 – 6621Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini67 – 8014CytoplasmicSequence analysisAdd
BLAST
Transmembranei81 – 10121Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini102 – 1032ExtracellularSequence analysis
Transmembranei104 – 12421Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini125 – 1306CytoplasmicSequence analysis
Transmembranei131 – 15121Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini152 – 16312ExtracellularSequence analysisAdd
BLAST
Transmembranei164 – 18421Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini185 – 24359CytoplasmicSequence analysisAdd
BLAST
Transmembranei244 – 26421Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini265 – 28016ExtracellularSequence analysisAdd
BLAST
Transmembranei281 – 30121Helical; Name=8Sequence analysisAdd
BLAST
Topological domaini302 – 3098CytoplasmicSequence analysis
Transmembranei310 – 33021Helical; Name=9Sequence analysisAdd
BLAST
Topological domaini331 – 3377ExtracellularSequence analysis
Transmembranei338 – 35821Helical; Name=10Sequence analysisAdd
BLAST
Topological domaini359 – 37921CytoplasmicSequence analysisAdd
BLAST
Transmembranei380 – 40021Helical; Name=11Sequence analysisAdd
BLAST
Topological domaini401 – 4011ExtracellularSequence analysis
Transmembranei402 – 42221Helical; Name=12Sequence analysisAdd
BLAST
Topological domaini423 – 45735CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 457457D-xylose-proton symporterPRO_0000050296Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi387344.LVIS_0186.

Structurei

3D structure databases

ProteinModelPortaliO52733.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni254 – 2607Monosaccharide bindingBy similarity

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QNK. Bacteria.
ENOG410XNQK. LUCA.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O52733-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKVSTGFVY FFGALGGLLF GYDTGVISGA ILFIQKQMNL GSWQQGWVVS
60 70 80 90 100
AVLLGAILGA AIIGPSSDRF GRRKLLLLSA IIFFVGALGS AFSPEFWTLI
110 120 130 140 150
ISRIILGMAV GAASALIPTY LAELAPSDKR GTVSSLFQLM VMTGILLAYI
160 170 180 190 200
TNYSFSGFYT GWRWMLGFAA IPAALLFLGG LILPESPRFL VKSGHLDEAR
210 220 230 240 250
HVLDTMNKHD QVAVNKEIND IQESAKIVSG GWSELFGKMV RPSLIIGIGL
260 270 280 290 300
AIFQQVMGCN TVLYYAPTIF TDVGFGVSAA LLAHIGIGIF NVIVTAIAVA
310 320 330 340 350
IMDKIDRKKI VNIGAVGMGI SLFVMSIGMK FSGGSQTAAI ISVIALTVYI
360 370 380 390 400
AFFSATWGPV MWVMIGEVFP LNIRGLGNSF ASVINWTANM IVSLTFPSLL
410 420 430 440 450
DFFGTGSLFI GYGILCFASI WFVQKKVFET RNRSLEDIEA TLRAKTGEDA

AELSTTK
Length:457
Mass (Da):49,199
Last modified:June 1, 1998 - v1
Checksum:iE097EB2B67A92F67
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF045552 Genomic DNA. Translation: AAC95127.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF045552 Genomic DNA. Translation: AAC95127.1.

3D structure databases

ProteinModelPortaliO52733.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi387344.LVIS_0186.

Protein family/group databases

TCDBi2.A.1.1.41. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4107QNK. Bacteria.
ENOG410XNQK. LUCA.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Chaillou S., Bor Y.-C., Batt C.A., Postma P., Pouwels P.
    Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiXYLT_LACBR
AccessioniPrimary (citable) accession number: O52733
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: November 11, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.