ID   DALD_KLEPN              Reviewed;         455 AA.
AC   O52720;
DT   31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   16-JUN-2009, entry version 41.
DE   RecName: Full=D-arabinitol 4-dehydrogenase;
DE            EC=1.1.1.11;
GN   Name=dalD;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1033-5P14 / KAY2026;
RX   MEDLINE=98304087; PubMed=9639934;
RA   Heuel H., Shakeri-Garakani A., Turgut S., Lengeler J.W.;
RT   "Genes for D-arabinitol and ribitol catabolism from Klebsiella
RT   pneumoniae.";
RL   Microbiology 144:1631-1639(1998).
CC   -!- CATALYTIC ACTIVITY: D-arabinitol + NAD(+) = D-xylulose + NADH.
CC   -!- PATHWAY: Carbohydrate metabolism; D-arabinitol metabolism.
CC   -!- SUBUNIT: Monomer.
CC   -!- SIMILARITY: Belongs to the mannitol dehydrogenase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AF045245; AAC26498.1; -; Genomic_DNA.
DR   HSSP; O08355; 1LJ8.
DR   BRENDA; 1.1.1.11; 758.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0047813; F:D-arabinitol 4-dehydrogenase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR000669; Mannitol_DH_core.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; FALSE_NEG.
PE   3: Inferred from homology;
KW   NAD; Oxidoreductase.
FT   CHAIN         1    455       D-arabinitol 4-dehydrogenase.
FT                                /FTId=PRO_0000170735.
SQ   SEQUENCE   455 AA;  51022 MW;  2D446E5232778DD5 CRC64;
     MNNQFTWLHI GLGSFHRAHQ AWYLHRLIAS GDNRWRIAAG NIRNDAEQVV QALAAQGGRY
     VLETVSPEGE REYEEITSIQ KLLPWQAGLQ PLINEGANPQ TKVIAFTVTE GGYYLNTRHR
     LETSNPDLQA DLQGECKTIY GTLARILEKR MADNAGPLTL LNCDNVRHNG ERFHDGMVEF
     LQLTGKQAVI DWMAANTTCP NTMVDRITPR PAADLPARIK AQAGIDDKAP VMGETFIQWV
     VENNFRDVRP NLEAVGVEMV ESVIPYEEAK IRILNASHSC IAWAGTLIGQ QYIHESTLTD
     VIYAIADRYV TEDVIPCLGD NGIDLPTYRD VVLKRFTNPY IQDTNQRVAA DGFSKIPAMI
     APTLQECYQR GVRPEATAML PALFFVFMEQ WHKGTLPYQY QDGILDAQAV HEMFEAQDPV
     AVFARDKALF GDLANNADFL ALMREKVAAV YTLIN
//