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Reviewed, UniProtKB/Swiss-Prot O52720 (DALD_KLEPN)

Last modified November 25, 2008. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    D-arabinitol 4-dehydrogenase
    EC=1.1.1.11
Gene names
Name: dalD
OrganismKlebsiella pneumoniae
Taxonomic identifier573 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

D-arabinitol + NAD(+) = D-xylulose + NADH.

Pathway

Carbohydrate metabolism; D-arabinitol metabolism.

Subunit structure

Monomer.

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords

   LigandNAD
   Molecular functionOxidoreductase

Gene Ontology (GO)

   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionD-arabinitol 4-dehydrogenase activity

Inferred from electronic annotation. Source: EC

coenzyme binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 455455D-arabinitol 4-dehydrogenase
PRO_0000170735

Sequences

Sequence LengthMass (Da)Tools
O52720-1 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 2D446E5232778DD5

FASTA45551,022
        10         20         30         40         50         60 
MNNQFTWLHI GLGSFHRAHQ AWYLHRLIAS GDNRWRIAAG NIRNDAEQVV QALAAQGGRY 

        70         80         90        100        110        120 
VLETVSPEGE REYEEITSIQ KLLPWQAGLQ PLINEGANPQ TKVIAFTVTE GGYYLNTRHR 

       130        140        150        160        170        180 
LETSNPDLQA DLQGECKTIY GTLARILEKR MADNAGPLTL LNCDNVRHNG ERFHDGMVEF 

       190        200        210        220        230        240 
LQLTGKQAVI DWMAANTTCP NTMVDRITPR PAADLPARIK AQAGIDDKAP VMGETFIQWV 

       250        260        270        280        290        300 
VENNFRDVRP NLEAVGVEMV ESVIPYEEAK IRILNASHSC IAWAGTLIGQ QYIHESTLTD 

       310        320        330        340        350        360 
VIYAIADRYV TEDVIPCLGD NGIDLPTYRD VVLKRFTNPY IQDTNQRVAA DGFSKIPAMI 

       370        380        390        400        410        420 
APTLQECYQR GVRPEATAML PALFFVFMEQ WHKGTLPYQY QDGILDAQAV HEMFEAQDPV 

       430        440        450 
AVFARDKALF GDLANNADFL ALMREKVAAV YTLIN 

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References

[1]"Genes for D-arabinitol and ribitol catabolism from Klebsiella pneumoniae."
Heuel H., Shakeri-Garakani A., Turgut S., Lengeler J.W.
Microbiology 144:1631-1639(1998) [PubMed: 9639934] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 1033-5P14 / KAY2026.

Cross-references

Sequence databases

AF045245 Genomic DNA. Translation: AAC26498.1.

3D structure databases

HSSPHSSP built from PDB template 1LJ8 based on UniProtKB O08355.
ModBaseSearch...

Family and domain databases

InterProIPR013328. DHase_multihelical.
IPR013118. Mannitol_DHase_C.
IPR000669. Mannitol_DHase_core.
IPR013131. Mannitol_DHase_N.
IPR016040. NAD(P)-bd.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
PROSITEPS00974. MANNITOL_DHGENASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDALD_KLEPN
AccessionPrimary (citable) accession number: O52720
Entry history
Integrated into UniProtKB/Swiss-Prot: January 31, 2002
Last sequence update: June 1, 1998
Last modified: November 25, 2008
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents