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O52593 (PTAS_CLOTH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:Cthe_1029
OrganismClostridium thermocellum (strain ATCC 27405 / DSM 1237) [Complete proteome] [HAMAP]
Taxonomic identifier203119 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length332 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the phosphate acetyltransferase and butyryltransferase family.

Sequence caution

The sequence ABN52261.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 332332Phosphate acetyltransferase
PRO_0000179126

Sequences

Sequence LengthMass (Da)Tools
O52593 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: ED97F638D6C84583

FASTA33235,396
        10         20         30         40         50         60 
MSFLEQIIER AKSDVKTIVL PESTDLRVIK AASMIMKKGI AKVVLIGNEK EIKSLAGDID 

        70         80         90        100        110        120 
LEGVMIEDSL NSEKLEDYAN TLYELRKSKG MTIEAARETI KDPLYYGVMM VKKGEADGMV 

       130        140        150        160        170        180 
AGAVNSTANT LRPALQILKT APGTKLVSSF FVMVVPNCEY GHNGTFVYAD CGLVENPDAD 

       190        200        210        220        230        240 
QLSEIAISAS KSFEMLVGAK PQVAMLSYSS YGSAKSELTE KVIKATQLAK EKAPHLAIDG 

       250        260        270        280        290        300 
ELQVDAAIVP EVAKSKAKGS SVAGKANVLI FPDLDAGNIA YKLTQRLAKA EAYGPITQGL 

       310        320        330 
ARPVNDLSRG CSAEDIVGVA AITAVQAQYV KA 

« Hide

References

« Hide 'large scale' references
[1]Stevens D.R., Guerinot M.L., Lynd L.R.
Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete sequence of Clostridium thermocellum ATCC 27405."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D., Newcomb M., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27405 / DSM 1237.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF041841 Genomic DNA. Translation: AAB96951.1.
CP000568 Genomic DNA. Translation: ABN52261.1. Different initiation.
RefSeqYP_001037454.1. NC_009012.1.

3D structure databases

ProteinModelPortalO52593.
SMRO52593. Positions 1-327.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING203119.Cthe_1029.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN52261; ABN52261; Cthe_1029.
GeneID4811323.
KEGGcth:Cthe_1029.
PATRIC19515791. VBICloThe47081_1081.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053796.
KOK00625.
OMACQGFAKP.
OrthoDBEOG6BKJ5W.
ProtClustDBCLSK852494.

Enzyme and pathway databases

BioCycCTHE203119:GIW8-1065-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

InterProIPR012147. P_Ac_Bu_trans.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTAS_CLOTH
AccessionPrimary (citable) accession number: O52593
Secondary accession number(s): A3DE82
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 1, 1998
Last modified: November 13, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways