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Protein

HTH-type transcriptional regulator ArgP

Gene

argP

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Controls the transcription of genes involved in arginine and lysine metabolism.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi21 – 40H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator ArgPUniRule annotation
Gene namesi
Name:argPUniRule annotation
Synonyms:iciA
Ordered Locus Names:NT01EI_3363
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
Proteomesi
  • UP000001485 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001056441 – 297HTH-type transcriptional regulator ArgPAdd BLAST297

Proteomic databases

PRIDEiO52399.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi634503.NT01EI_3363.

Structurei

3D structure databases

ProteinModelPortaliO52399.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 60HTH lysR-typeUniRule annotationAdd BLAST57

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CXD. Bacteria.
COG0583. LUCA.
HOGENOMiHOG000219802.
KOiK05596.
OMAiSTCCMIP.
OrthoDBiPOG091H09MH.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00513. HTH_type_ArgP. 1 hit.
InterProiIPR017685. ArgP.
IPR023490. ArgP_Gammaproteobact.
IPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
TIGRFAMsiTIGR03298. argP. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O52399-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRPDYRTLQ ALDAVIRERG FERAAQKLCI TQSAVSQRIK QLENLFGQPL
60 70 80 90 100
LVRTVPPRPT EQGQRLLALL HQVELLEEEW LGNDNSSDGP LLLSLAVNAD
110 120 130 140 150
SLATWLLPAL KPVLADSPLR LNLQVEDESR TQERLRRGEV VGAVSLQPQP
160 170 180 190 200
LPSCLVDRLG ALDYLFCASP AFAARYFPNG VTRSSLLKAP AVAFDHLDDM
210 220 230 240 250
HQAFLQQNFE LPPGSVPCHI VNSSEAFVQL ALQGTTCCML PHLQVERELR
260 270 280 290
KGVLIDLTPG MVQRRMLYWH RFAPESRLMR RVTDALISHG RDVLRQD
Length:297
Mass (Da):33,393
Last modified:June 1, 1998 - v1
Checksum:i93BEC456B2419989
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037440 Genomic DNA. Translation: AAB92569.1.
CP001600 Genomic DNA. Translation: ACR70500.1.
RefSeqiWP_015872573.1. NC_012779.2.

Genome annotation databases

EnsemblBacteriaiACR70500; ACR70500; NT01EI_3363.
GeneIDi7959662.
KEGGieic:NT01EI_3363.
PATRICi21839458. VBIEdwIct114273_2989.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037440 Genomic DNA. Translation: AAB92569.1.
CP001600 Genomic DNA. Translation: ACR70500.1.
RefSeqiWP_015872573.1. NC_012779.2.

3D structure databases

ProteinModelPortaliO52399.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634503.NT01EI_3363.

Proteomic databases

PRIDEiO52399.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR70500; ACR70500; NT01EI_3363.
GeneIDi7959662.
KEGGieic:NT01EI_3363.
PATRICi21839458. VBIEdwIct114273_2989.

Phylogenomic databases

eggNOGiENOG4105CXD. Bacteria.
COG0583. LUCA.
HOGENOMiHOG000219802.
KOiK05596.
OMAiSTCCMIP.
OrthoDBiPOG091H09MH.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00513. HTH_type_ArgP. 1 hit.
InterProiIPR017685. ArgP.
IPR023490. ArgP_Gammaproteobact.
IPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
TIGRFAMsiTIGR03298. argP. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARGP_EDWI9
AccessioniPrimary (citable) accession number: O52399
Secondary accession number(s): C5BAU1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 1, 1998
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.