O52070 (FLGE_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Flagellar hook protein FlgE

Gene names

Name:	flgE
Ordered Locus Names:	BruAb2_1076

Organism

Brucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]

Taxonomic identifier

262698 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus › Brucella abortus bv. 1

Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Bacterial flagellum basal body.
Sequence similarities	Belongs to the flagella basal body rod proteins family.
Caution	Brucella species display species-specific inactivation of flagellar genes and are consequently nonmotile.

Ontologies

Keywords
Cellular component	Bacterial flagellum
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ciliary or flagellar motility Inferred from electronic annotation. Source: InterPro
Cellular_component	bacterial-type flagellum basal body, rod Inferred from electronic annotation. Source: InterPro
Molecular_function	motor activity Inferred from electronic annotation. Source: InterPro structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 396	396	Flagellar hook protein FlgE		PRO_0000180819
Experimental info
	Sequence conflict	213	1	N → D in AAC01569. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	O52070 [UniParc]. Last modified July 5, 2005. Version 2. Checksum: 7B0A928981DC566A	FASTA	396	40,848
	10 20 30 40 50 60 MSLYGMMRTG VSGMNAQANR LSTVADNIAN ASTVGYKRAE TQFSSLVLPS TAGQYNSGSV 70 80 90 100 110 120 LTDVRYGISD QGGIRSTSST TDLAIDGNGY FVVQGPGGST YLTRAGSFVP DKNGDLVNSA 130 140 150 160 170 180 GYYLLGAGAD EAAGGLTVAG LNVVNVNAAA LPAEGSTAGD FTVNLPSTDQ APAAGGYNHK 190 200 210 220 230 240 TSLISYNDKG EKITLDVYFT KTGADEWNVS VKNAADGVEI GTTVLNFDPT TGDLVSGGNV 250 260 270 280 290 300 AVNLGAYGGQ TLNLNLGGST QRAGDYTISQ AVINGQAPSS IKGVDVGNDG AVVAVYENGT 310 320 330 340 350 360 QKVLYRIPLA NVASPDRMTV VSGNIFLPSA ESGDVRLGFP QGDGMGKIMS GTLEESNADI 370 380 390 AQELTDMIEA QRSYTANSKV FQTGFELMDV LVNLKR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"On the presence and organization of open reading frames of the nonmotile pathogen Brucella abortus similar to class II, III, and IV flagellar genes and to LcrD virulence superfamily." Halling S.M. Microb. Comp. Genomics 3:21-29(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 544 / Biovar 1.
[2]	"Flagellar region in the genome of Brucella abortus 544." Fretin D., Fauconnier A., Tibor A., Bellefontaine A.-F., Vandenhaute J., Letesson J.-J. Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 544 / Biovar 1.
[3]	"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF019252 Genomic DNA. Translation: AAC01569.1. AF325192 Genomic DNA. Translation: AAG52877.1. AE017224 Genomic DNA. Translation: AAX76449.1.
RefSeq	YP_223810.1. NC_006933.1.
3D structure databases
ProteinModelPortal	O52070.
ModBase	Search...
Protein-protein interaction databases
STRING	262698.BruAb2_1076.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAX76449; AAX76449; BruAb2_1076.
GeneID	3341564.
KEGG	bmb:BruAb2_1076.
PATRIC	17828501. VBIBruAbo15061_3410.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1749.
HOGENOM	HOG000254240.
KO	K02390.
OMA	YPANEAT.
ProtClustDB	PRK05682.
Enzyme and pathway databases
BioCyc	BABO262698:GJC2-3305-MONOMER.
Family and domain databases
InterPro	IPR011491. Falgellar_basal_body_FlaE. IPR001444. Flag_bb_rod_N. IPR019776. Flagellar_basal_body_rod_CS. IPR020013. Flagellar_FlgE/F/G. IPR010930. Flg_bb/hook_C_dom. [Graphical view]
Pfam	PF07559. FlaE. 1 hit. PF00460. Flg_bb_rod. 1 hit. PF06429. Flg_bbr_C. 1 hit. [Graphical view]
TIGRFAMs	TIGR03506. FlgEFG_subfam. 1 hit.
PROSITE	PS00588. FLAGELLA_BB_ROD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FLGE_BRUAB

Accession

Primary (citable) accession number: O52070
Secondary accession number(s): Q576I5, Q9AMF5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	July 5, 2005
Last modified:	May 1, 2013
This is version 64 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program