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Protein

Flagellar filament 35 kDa core protein

Gene

flaB

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the core of the flagella.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciLINT189518:GJBB-1627-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar filament 35 kDa core protein
Alternative name(s):
35 kDa antigen
Flagellin class B
Gene namesi
Name:flaB
Synonyms:flaB2
Ordered Locus Names:LA_2019
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000001408 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 283283Flagellar filament 35 kDa core proteinPRO_0000182616Add
BLAST

Interactioni

Subunit structurei

The flagellum consists of two outer layers around a core that contains several antigenically related polypeptides.

Protein-protein interaction databases

STRINGi189518.LA_2019.

Structurei

3D structure databases

ProteinModelPortaliO51941.
SMRiO51941. Positions 242-280.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial flagellin family.Curated

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
InParanoidiO51941.
KOiK02406.
OMAiSHRSEIG.

Family and domain databases

Gene3Di1.20.1330.10. 1 hit.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.

Sequencei

Sequence statusi: Complete.

O51941-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIINHNLSAV NAHRSLKFNE LAVDKTMKAL SSGMRINSAA DDASGLAVSE
60 70 80 90 100
KLRTQINGLR QAERNTEDGM SFIQTAEGFL EQTSNIIQRI RVLAIQTSNG
110 120 130 140 150
IYSNEDRQLV QVEVSALVDE VDRIASQAEF NKFKLFEGQF ARGSRVASMW
160 170 180 190 200
FHMGPNQNQR ERFYIGTMTS KALKLVKADG RPIAISSPGE ANDVIGLADA
210 220 230 240 250
ALTKIMKQRA DMGAYYNRLE YTAKGLMGAY ENMQASESRI RDADMAEEVV
260 270 280
SLTTKQILVQ SGTAMLAQAN MKPNSVLKLL QQI
Length:283
Mass (Da):31,272
Last modified:December 6, 2002 - v2
Checksum:i0C1ED44A7057F856
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti56 – 561I → V in AAB94024 (PubMed:9317049).Curated
Sequence conflicti268 – 2681Q → R in AAB94024 (PubMed:9317049).Curated
Sequence conflicti282 – 2821Q → H in AAB94024 (PubMed:9317049).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF014114 Genomic DNA. Translation: AAB94024.1.
AE010300 Genomic DNA. Translation: AAN49218.1.
RefSeqiNP_712200.1. NC_004342.2.
WP_000586168.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN49218; AAN49218; LA_2019.
GeneIDi1151362.
KEGGilil:LA_2019.
PATRICi22384889. VBILepInt91350_2015.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF014114 Genomic DNA. Translation: AAB94024.1.
AE010300 Genomic DNA. Translation: AAN49218.1.
RefSeqiNP_712200.1. NC_004342.2.
WP_000586168.1. NC_004342.2.

3D structure databases

ProteinModelPortaliO51941.
SMRiO51941. Positions 242-280.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA_2019.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN49218; AAN49218; LA_2019.
GeneIDi1151362.
KEGGilil:LA_2019.
PATRICi22384889. VBILepInt91350_2015.

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
InParanoidiO51941.
KOiK02406.
OMAiSHRSEIG.

Enzyme and pathway databases

BioCyciLINT189518:GJBB-1627-MONOMER.

Family and domain databases

Gene3Di1.20.1330.10. 1 hit.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.
ProtoNetiSearch...

Entry informationi

Entry nameiFLAB_LEPIN
AccessioniPrimary (citable) accession number: O51941
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: December 6, 2002
Last modified: September 7, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.