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Protein

RNA polymerase sigma factor RpoS

Gene

rpoS

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response (By similarity). May be required for the persistence of V.cholerae in aquatic habitats.UniRule annotation1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi289 – 308H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Sigma factor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciVCHO:VC0534-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor RpoSUniRule annotation
Alternative name(s):
Sigma SUniRule annotation
Sigma-38UniRule annotation
Gene namesi
Name:rpoSUniRule annotation
Ordered Locus Names:VC_0534
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000939761 – 335RNA polymerase sigma factor RpoSAdd BLAST335

Interactioni

Subunit structurei

Interacts with the RNA polymerase core enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi243277.VC0534

Structurei

3D structure databases

ProteinModelPortaliO51804
SMRiO51804
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni57 – 90Sigma-70 factor domain-1UniRule annotationAdd BLAST34
Regioni95 – 165Sigma-70 factor domain-2UniRule annotationAdd BLAST71
Regioni175 – 250Sigma-70 factor domain-3UniRule annotationAdd BLAST76
Regioni263 – 316Sigma-70 factor domain-4UniRule annotationAdd BLAST54

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi119 – 122Interaction with polymerase core subunit RpoC4

Sequence similaritiesi

Belongs to the sigma-70 factor family. RpoS subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DG1 Bacteria
COG0568 LUCA
KOiK03087
OMAiITNRESQ

Family and domain databases

Gene3Di1.10.10.10, 2 hits
HAMAPiMF_00959 Sigma70_RpoS, 1 hit
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR009042 RNA_pol_sigma70_r1_2
IPR007627 RNA_pol_sigma70_r2
IPR007624 RNA_pol_sigma70_r3
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR012761 RNA_pol_sigma_RpoS
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00140 Sigma70_r1_2, 1 hit
PF04542 Sigma70_r2, 1 hit
PF04539 Sigma70_r3, 1 hit
PF04545 Sigma70_r4, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 2 hits
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02394 rpoS_proteo, 1 hit
TIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit
PS00716 SIGMA70_2, 1 hit

Sequencei

Sequence statusi: Complete.

O51804-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVSNTVTKV EEFDFEDEAL EVLETDAELT SDEELVAVEG ASEDVREEFD
60 70 80 90 100
ASAKSLDATQ MYLSEIGFSP LLTAEEEVLY ARRALRGDEA ARKRMIESNL
110 120 130 140 150
RLVVKISRRY SNRGLALLDL IEEGNLGLIR AVEKFDPERG FRFSTYATWW
160 170 180 190 200
IRQTIERALM NQTRTIRLPI HVVKELNIYL RTARELSQRL DHEPTPEEIA
210 220 230 240 250
LELDRPVDDV TKMLRLNERI SSVDTPIGGD GDKALLDILP DSHNADPEFS
260 270 280 290 300
TQDDDIRESL LNWLDELNPK QKEVLARRFG LLGYEPSTLE EVGREINLTR
310 320 330
ERVRQIQVEG LRRLREILVK QGLNMEALFN VEYDN
Length:335
Mass (Da):38,534
Last modified:June 1, 1998 - v1
Checksum:i26512CCE15CE2748
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000945 Genomic DNA Translation: AAC38175.1
AE003852 Genomic DNA Translation: AAF93702.1
PIRiA82312
RefSeqiNP_230185.1, NC_002505.1
WP_000116737.1, NC_002505.1

Genome annotation databases

EnsemblBacteriaiAAF93702; AAF93702; VC_0534
GeneIDi2615203
KEGGivch:VC0534
PATRICifig|243277.26.peg.510

Similar proteinsi

Entry informationi

Entry nameiRPOS_VIBCH
AccessioniPrimary (citable) accession number: O51804
Secondary accession number(s): Q9JQ13
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: June 1, 1998
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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