O51733 (O51733_BORBU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Thymidylate kinase EMBL AAC67140.2
EC=2.7.4.9 EMBL AAC67140.2

Gene names

Name:	tmk EMBL AAC67140.2
Ordered Locus Names:	BB_0793 EMBL AAC67140.2

Organism

Borrelia burgdorferi (Lyme disease spirochete)

Taxonomic identifier

139 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	202 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity

ATP + dTMP = ADP + dTDP. SAAS SAAS018095

Ontologies

Keywords
Biological process	Nucleotide biosynthesis SAAS SAAS018095
Ligand	ATP-binding SAAS SAAS018095 Nucleotide-binding
Molecular function	Kinase SAAS SAAS018095 EMBL AAC67140.2 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dTDP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW thymidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O51733 [UniParc]. Last modified January 25, 2012. Version 2. Checksum: 763BC7CC746DBA9C	FASTA	202	23,790
	10 20 30 40 50 60 MIKILKNFYC IEGIDGSGKT SITNKLKALC NDESRYYFTK EPSSGIIGEM IRKQLMNFEN 70 80 90 100 110 120 PLEESTFAYL YAADRHDHLY KKGGILEILN TKSRKIITDR YLFSSIAYQG KLGYELNKNF 130 140 150 160 170 180 PLPEKVFFIE TDPNIAYERI QKNRTQSDLF ELEKYKTFEQ IALKYLKIFK KLEKKINVIY 190 200 INNSIKDNLD KNAKKIFNLI KF

References

[1]

"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi." Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. , Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B., Smith H.O., Venter J.C. Nature 390:580-586(1997) [PubMed: 9403685] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000783 Genomic DNA. Translation: AAC67140.2.
RefSeq	NP_212927.1. NC_001318.1.
3D structure databases
ProteinModelPortal	O51733.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1195651.
KEGG	bbu:BB0793.
PATRIC	20558251. VBIBorBur75917_1185.
Family and domain databases
HAMAP	MF_00165. Thymidylate_kinase. [Tree]
InterPro	IPR018095. Thymidylate_kin_CS. IPR018094. Thymidylate_kinase. [Graphical view]
Pfam	PF02223. Thymidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00041. DTMP_kinase. 1 hit.
PROSITE	PS01331. THYMIDYLATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O51733_BORBU

Accession

Primary (citable) accession number: O51733

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	January 25, 2012
Last modified:	January 25, 2012
This is version 67 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)