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O51672

- G6PI_BORBU

UniProt

O51672 - G6PI_BORBU

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donorBy similarity
Active sitei387 – 3871By similarity
Active sitei502 – 5021By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBBUR224326:G9SO-739-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:BB_0730
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
ProteomesiUP000001807: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 530530Glucose-6-phosphate isomerasePRO_0000180606Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224326.BB0730.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O51672 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLNYKNLNEL ENFKILEGIA PEVLKTALTG KRIKEYDITI EGDSVHYNYA
60 70 80 90 100
SKQINETHLK IFQNLSDEAN LIEKYKEVLD GEKINISENR KVLHHLTRGQ
110 120 130 140 150
IGKDVIEDNK ENMREFFQSE LEKIYNFAKQ IHSGNIKSSN GKKFKNVVQI
160 170 180 190 200
GIGGSSLGPK ALYSSIKNYA KKHNLALMNG YFISNIDPDE SEEVLSSINV
210 220 230 240 250
DETLFIIVSK SGNTLETKAN MQFLINKLKL NGIKEYKKQM VIITLKDSML
260 270 280 290 300
AIEEKGYLEY FFMHDSIGGR FSPTSAVGLT LLTLCFTEKV AKEILKGANE
310 320 330 340 350
ADKKSLNKNV KDNASLLAAL ISIYERNVLN YSSNCIIAYS KAMENFYLHL
360 370 380 390 400
QQLEMESNGK SVNRFNETIN YKTVRIIWGG IGTDVQHSFF QMLHQGTDIV
410 420 430 440 450
PMDFIGFNET QLKEDVISDN SSSNDKLKAN LIAQIIAFSK GKENSNKNKN
460 470 480 490 500
FQGERPSALI YSKELTPYAI GAILSHYENK VMFEGFLLNI NSFDQEGVQL
510 520 530
GKIIANQILK NDNFKDEVIE SYSKKILKKF
Length:530
Mass (Da):60,121
Last modified:April 18, 2012 - v2
Checksum:i15C0F8B0CB6AE312
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000783 Genomic DNA. Translation: AAC67084.2.
PIRiA70191.
RefSeqiNP_212864.2. NC_001318.1.

Genome annotation databases

EnsemblBacteriaiAAC67084; AAC67084; BB_0730.
GeneIDi1195584.
KEGGibbu:BB_0730.
PATRICi20558117. VBIBorBur75917_1122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000783 Genomic DNA. Translation: AAC67084.2 .
PIRi A70191.
RefSeqi NP_212864.2. NC_001318.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224326.BB0730.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC67084 ; AAC67084 ; BB_0730 .
GeneIDi 1195584.
KEGGi bbu:BB_0730.
PATRICi 20558117. VBIBorBur75917_1122.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci BBUR224326:G9SO-739-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Entry informationi

Entry nameiG6PI_BORBU
AccessioniPrimary (citable) accession number: O51672
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: April 18, 2012
Last modified: October 29, 2014
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3