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O51672

- G6PI_BORBU

UniProt

O51672 - G6PI_BORBU

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 2 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei356 – 3561Proton donorBy similarity
    Active sitei387 – 3871By similarity
    Active sitei502 – 5021By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciBBUR224326:G9SO-739-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase (EC:5.3.1.9)
    Short name:
    GPI
    Alternative name(s):
    Phosphoglucose isomerase
    Short name:
    PGI
    Phosphohexose isomerase
    Short name:
    PHI
    Gene namesi
    Name:pgi
    Ordered Locus Names:BB_0730
    OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
    Taxonomic identifieri224326 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
    ProteomesiUP000001807: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 530530Glucose-6-phosphate isomerasePRO_0000180606Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi224326.BB0730.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O51672-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLNYKNLNEL ENFKILEGIA PEVLKTALTG KRIKEYDITI EGDSVHYNYA    50
    SKQINETHLK IFQNLSDEAN LIEKYKEVLD GEKINISENR KVLHHLTRGQ 100
    IGKDVIEDNK ENMREFFQSE LEKIYNFAKQ IHSGNIKSSN GKKFKNVVQI 150
    GIGGSSLGPK ALYSSIKNYA KKHNLALMNG YFISNIDPDE SEEVLSSINV 200
    DETLFIIVSK SGNTLETKAN MQFLINKLKL NGIKEYKKQM VIITLKDSML 250
    AIEEKGYLEY FFMHDSIGGR FSPTSAVGLT LLTLCFTEKV AKEILKGANE 300
    ADKKSLNKNV KDNASLLAAL ISIYERNVLN YSSNCIIAYS KAMENFYLHL 350
    QQLEMESNGK SVNRFNETIN YKTVRIIWGG IGTDVQHSFF QMLHQGTDIV 400
    PMDFIGFNET QLKEDVISDN SSSNDKLKAN LIAQIIAFSK GKENSNKNKN 450
    FQGERPSALI YSKELTPYAI GAILSHYENK VMFEGFLLNI NSFDQEGVQL 500
    GKIIANQILK NDNFKDEVIE SYSKKILKKF 530
    Length:530
    Mass (Da):60,121
    Last modified:April 18, 2012 - v2
    Checksum:i15C0F8B0CB6AE312
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000783 Genomic DNA. Translation: AAC67084.2.
    PIRiA70191.
    RefSeqiNP_212864.2. NC_001318.1.

    Genome annotation databases

    EnsemblBacteriaiAAC67084; AAC67084; BB_0730.
    GeneIDi1195584.
    KEGGibbu:BB_0730.
    PATRICi20558117. VBIBorBur75917_1122.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000783 Genomic DNA. Translation: AAC67084.2 .
    PIRi A70191.
    RefSeqi NP_212864.2. NC_001318.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224326.BB0730.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC67084 ; AAC67084 ; BB_0730 .
    GeneIDi 1195584.
    KEGGi bbu:BB_0730.
    PATRICi 20558117. VBIBorBur75917_1122.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci BBUR224326:G9SO-739-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

    Entry informationi

    Entry nameiG6PI_BORBU
    AccessioniPrimary (citable) accession number: O51672
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 89 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3