O51631 (O51631_BORBU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mevalonate kinase EMBL AAC67029.1
EC=2.7.1.36 EMBL AAC67029.1

Gene names

Name:	mvk EMBL AAC67029.1
Ordered Locus Names:	BB_0688

Organism

Borrelia burgdorferi (Lyme disease spirochete)

Taxonomic identifier

139 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	297 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Kinase EMBL AAC67029.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	isoprenoid biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW mevalonate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O51631 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: A3DF67372C10D082	FASTA	297	33,103
	10 20 30 40 50 60 MLRIRKPAKI LFLGEHSAVY GFPVIGATVP IYMDLIYSVS KNWKYLGKPS TRLNSLISFI 70 80 90 100 110 120 VSNYSKVNPI EFDIISEIPI GVGLGSSASL SLCFAEYITS HFEYKDCNKI LLANQIENIF 130 140 150 160 170 180 HGKSSGMDIR LIDLNGTFYL EKKENVLHSK KIKDSGFYFL IGAIKRDLTT KEIVVNLKKD 190 200 210 220 230 240 LLSNAYLFVF IEKLGLAVSN SYASFQNKDV YSLANEMNIA QCCLKRLGLS NDTLDWLISE 250 260 270 280 290 GIKLGALSGK LSGAGKGGAF IFLFESLIKA NIVQKELNNM LKDSKIDLLL KLKVIET

References

[1]

"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi." Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. , Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B., Smith H.O., Venter J.C. Nature 390:580-586(1997) [PubMed: 9403685] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000783 Genomic DNA. Translation: AAC67029.1.
PIR	G70185.
RefSeq	NP_212822.1. NC_001318.1.
3D structure databases
ProteinModelPortal	O51631.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000008709; EBBORP00000008039; EBBORG00000008708.
GeneID	1195540.
GenomeReviews	Gene locus BB_0688 in contig AE000783_GR.
KEGG	bbu:BB0688.
NMPDR	fig|224326.1.peg.1072.
PATRIC	20558025. VBIBorBur75917_1079.
TIGR	BB_0688.
Phylogenomic databases
GeneTree	EBGT00050000007331.
HOGENOM	HBG354481.
OMA	HSAVYGF.
ProtClustDB	CLSK507764.
Family and domain databases
InterPro	IPR006204. GHMP_kinase. IPR013750. GHMP_kinase_C. IPR006203. GHMP_knse_ATP-bd_CS. IPR006205. Mev_gal_kin. IPR006206. Mevalonate/galactokinase. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
Pfam	PF08544. GHMP_kinases_C. 1 hit. PF00288. GHMP_kinases_N. 1 hit. [Graphical view]
PRINTS	PR00959. MEVGALKINASE.
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00549. Mevalon_kin. 1 hit.
PROSITE	PS00627. GHMP_KINASES_ATP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O51631_BORBU

Accession

Primary (citable) accession number: O51631

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	January 25, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)