ID   RPIA_BORBU              Reviewed;         228 AA.
AC   O51601;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   16-JUN-2009, entry version 55.
DE   RecName: Full=Ribose-5-phosphate isomerase A;
DE            EC=5.3.1.6;
DE   AltName: Full=Phosphoriboisomerase A;
DE            Short=PRI;
GN   Name=rpiA; OrderedLocusNames=BB_0657;
OS   Borrelia burgdorferi (Lyme disease spirochete).
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia;
OC   Borrelia burgdorferi group.
OX   NCBI_TaxID=139;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / B31 / CIP 102532 / DSM 4680;
RX   MEDLINE=98065943; PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K.,
RA   Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D.,
RA   Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J.,
RA   Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D.,
RA   Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A.,
RA   Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K.,
RA   Roberts K.M., Hatch B., Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia
RT   burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- CATALYTIC ACTIVITY: D-ribose 5-phosphate = D-ribulose 5-phosphate.
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative
CC       stage): step 1/1.
CC   -!- SIMILARITY: Belongs to the ribose 5-phosphate isomerase family.
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DR   EMBL; AE000783; AAC67008.1; -; Genomic_DNA.
DR   PIR; H70181; H70181.
DR   RefSeq; NP_212791.1; -.
DR   HSSP; O50083; 1LK5.
DR   GeneID; 1195509; -.
DR   GenomeReviews; AE000783_GR; BB_0657.
DR   KEGG; bbu:BB0657; -.
DR   NMPDR; fig|224326.1.peg.1041; -.
DR   TIGR; BB_0657; -.
DR   HOGENOM; O51601; -.
DR   OMA; O51601; EVIPMAI.
DR   BioCyc; BBUR224326:BB_0657-MON; -.
DR   BRENDA; 5.3.1.6; 142596.
DR   GO; GO:0004751; F:ribose-5-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:HAMAP.
DR   HAMAP; MF_00170; -; 1.
DR   InterPro; IPR004788; RpiA.
DR   PANTHER; PTHR11934; RpiA; 1.
DR   Pfam; PF06026; Rib_5-P_isom_A; 1.
DR   ProDom; PD005813; RpiA; 1.
DR   TIGRFAMs; TIGR00021; rpiA; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase.
FT   CHAIN         1    228       Ribose-5-phosphate isomerase A.
FT                                /FTId=PRO_0000158392.
SQ   SEQUENCE   228 AA;  25885 MW;  4051FC370FF7C76F CRC64;
     MENQKILVAK HAIDHYIKSN MNLGIGTGTT IYYAIKYLSE KIKSGSLKNL KFYTTSSDTK
     YLLSKEQIPY ESNFSKLNKN LDIAIDGADE ILLEKKSLIK GMGGAHLMEK VIAYNSETLL
     IIADETKIVK KLGTKMPIPI EVAQNAVGFI MTRLEEMNLE ATLRICKEKK GPTITDNNNY
     ILDVKMHVEN PEGTEKYFKL FPGILEIGIF NHKNTRIVYY QDKQIKEA
//