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Protein

Probable M18 family aminopeptidase 2

Gene

apeB

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi84ZincSequence analysis1
Metal bindingi157ZincSequence analysis1
Metal bindingi397ZincSequence analysis1

GO - Molecular functioni

Keywordsi

Molecular functionAminopeptidase, Hydrolase, Metalloprotease, Protease
LigandMetal-binding, Zinc

Protein family/group databases

MEROPSiM18.002.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable M18 family aminopeptidase 2 (EC:3.4.11.-)
Gene namesi
Name:apeB
Ordered Locus Names:BB_0627
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: CAFA

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001734601 – 423Probable M18 family aminopeptidase 2Add BLAST423

Proteomic databases

PRIDEiO51572.

Structurei

3D structure databases

ProteinModelPortaliO51572.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M18 family.Curated

Phylogenomic databases

OMAiCFDHEEI.

Family and domain databases

CDDicd05639. M18. 1 hit.
HAMAPiMF_00467. Aminopeptidase_M18_2. 1 hit.
InterProiView protein in InterPro
IPR033818. Aminopeptidase_I.
IPR022984. M18_aminopeptidase_2.
IPR001948. Peptidase_M18.
PfamiView protein in Pfam
PF02127. Peptidase_M18. 1 hit.
PRINTSiPR00932. AMINO1PTASE.

Sequencei

Sequence statusi: Complete.

O51572-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVXXKTLEPK FFQSLLDNSP TPYHLVNYIE EKLINYFNAQ QLKLNEKWKI
60 70 80 90 100
KTGSYYIKKE GTSLIAFNID VKKKYEPFLI AAAHTDSPGL KLKIDATEKV
110 120 130 140 150
SGVFYNHIEV YGSPIISTWI DRDLSLAGIV YFKKNENIES KLINIENIGI
160 170 180 190 200
IPNLAIHLNR QINEGFKYNA HDNLTVISST KKAIKDNILE QLGIECENFL
210 220 230 240 250
SCDLIFTESQ PSKIIGTEGE FLASKNLDNK SGCHAIMNSY VHTSNDKNKI
260 270 280 290 300
AVFFDNEEVG SLTSRGADSN FLSEVLERID IALDLTREEH LIKTNKSFNI
310 320 330 340 350
SIDSVHGIHP GYTSKHDPNY QANLGKGVVV KNSANFRYAT TSTGFAKLKN
360 370 380 390 400
LAIKNNIKIQ EIIMKANVPS GTTIGPISNA RTGIETIDIG TPMWAMHSLR
410 420
ETVSIADHIE AIKLLRAFFE KGI
Length:423
Mass (Da):47,381
Last modified:June 1, 1998 - v1
Checksum:iBE62EEF05A2B100B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000783 Genomic DNA. No translation available.
PIRiB70178.
RefSeqiWP_023003298.1. NC_001318.1.
YP_008686584.1. NC_001318.1.

Genome annotation databases

GeneIDi1195478.
KEGGibbu:BB_0627.
PATRICifig|224326.49.peg.1017.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000783 Genomic DNA. No translation available.
PIRiB70178.
RefSeqiWP_023003298.1. NC_001318.1.
YP_008686584.1. NC_001318.1.

3D structure databases

ProteinModelPortaliO51572.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiM18.002.

Proteomic databases

PRIDEiO51572.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1195478.
KEGGibbu:BB_0627.
PATRICifig|224326.49.peg.1017.

Phylogenomic databases

OMAiCFDHEEI.

Family and domain databases

CDDicd05639. M18. 1 hit.
HAMAPiMF_00467. Aminopeptidase_M18_2. 1 hit.
InterProiView protein in InterPro
IPR033818. Aminopeptidase_I.
IPR022984. M18_aminopeptidase_2.
IPR001948. Peptidase_M18.
PfamiView protein in Pfam
PF02127. Peptidase_M18. 1 hit.
PRINTSiPR00932. AMINO1PTASE.
ProtoNetiSearch...

Entry informationi

Entry nameiAPEB_BORBU
AccessioniPrimary (citable) accession number: O51572
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2001
Last sequence update: June 1, 1998
Last modified: June 7, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.