Reviewed, UniProtKB/Swiss-Prot O51535 (PTA_BORBU)

Names and origin

Protein names

Recommended name:
    Phosphate acetyltransferase
    EC=2.3.1.8
Alternative name(s):
    Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	BB_0589

Organism

Borrelia burgdorferi (Lyme disease spirochete) [Complete proteome] [HAMAP]

Taxonomic identifier

139 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 352	352	Phosphate acetyltransferase		PRO_0000179121

Sequences

	Sequence		Length	Mass (Da)
	O51535-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 57B2B6A94CC99A53	FASTA	352	38,846
	10 20 30 40 50 60 MLYSFYKVFC LKDYVFKKAR IFVKENKLKA NIVFPESSDS RVLKAAIVIL QKNLADSIIL 70 80 90 100 110 120 IGKKDTVINS LKEFSNCNDI LGRIEVVDPN SFPDIEMYLD EYWSLQKLKG VTKQSLKTQV 130 140 150 160 170 180 LDEITFAMLM VRFGYAKSCV CGAVSTSAKV LSNALRIIPK LEGVKIISSF MIMDTLCTAR 190 200 210 220 230 240 NVDFCFGHNG ILFFADCSVV VNPNSLELAE IALQSAKSFK DILNAKPKVA LLSFSTKGSS 250 260 270 280 290 300 SAKETEKVKN ALNIVRNKES DLLIDGELQL DSAIIKDVAE KKCRESLVAG SANVLIFPNL 310 320 330 340 350 DAGNIGYKLV ERFAFAKAYG PFLQGFSKPI SDLSRGCSVD EIVFASALMI SI

References

[1]

"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi." Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. , Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B., Smith H.O., Venter J.C. Nature 390:580-586(1997) [PubMed: 9403685] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000783 Genomic DNA. Translation: AAB91518.1.
PIR	D70173.
RefSeq	NP_212723.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1195436.
GenomeReviews	Gene locus BB_0589 in contig AE000783_GR.
KEGG	bbu:BB0589.
NMPDR	fig|224326.1.peg.973.
TIGR	BB_0589.
Phylogenomic databases
HOGENOM	O51535.
OMA	PDLQAGN.
Enzyme and pathway databases
BioCyc	BBUR224326:BB_0589-MON.
BRENDA	2.3.1.8. 142596.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTA_BORBU

Accession

Primary (citable) accession number: O51535

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	June 1, 1998
Last modified:	November 3, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)