O51318 (GATC_BORBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit C
Short name=Glu-ADT subunit C
EC=6.3.5.-

Gene names

Name:	gatC
Ordered Locus Names:	BB_0343

Organism

Borrelia burgdorferi (Lyme disease spirochete)

Taxonomic identifier

139 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) By similarity. HAMAP MF_00122
Catalytic activity	ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. HAMAP MF_00122 ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate. HAMAP MF_00122
Subunit structure	Heterotrimer of A, B and C subunits By similarity. HAMAP MF_00122
Sequence similarities	Belongs to the GatC family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of translational fidelity Inferred from electronic annotation. Source: InterPro translation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 91	91	Glutamyl-tRNA(Gln) amidotransferase subunit C HAMAP MF_00122		PRO_0000105279

Sequences

	Sequence		Length	Mass (Da)
	O51318 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 146C23A0CC02A6FB	FASTA	91	10,524
	10 20 30 40 50 60 MKDIHLKNSL KLSLVTLSRE SEDKFISKFE KVIKLVNKIS NFEVQINFNA NKKKISTLRE 70 80 90 DKVEFSLSIE AIKKLSNSFL DGYFSSPKIL E

References

[1]

"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi." Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. , Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B., Smith H.O., Venter J.C. Nature 390:580-586(1997) [PubMed: 9403685] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000783 Genomic DNA. Translation: AAC66714.1.
PIR	F70142.
RefSeq	NP_212477.1. NC_001318.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000008777; EBBORP00000008107; EBBORG00000008776.
GeneID	1195180.
GenomeReviews	Gene locus BB_0343 in contig AE000783_GR.
KEGG	bbu:BB0343.
NMPDR	fig|224326.1.peg.727.
PATRIC	20557298. VBIBorBur75917_0739.
TIGR	BB_0343.
Phylogenomic databases
GeneTree	EBGT00050000007139.
HOGENOM	HBG354812.
OMA	IHLENSL.
ProtClustDB	PRK00034.
Enzyme and pathway databases
BioCyc	BBUR224326:BB_0343-MONOMER.
Family and domain databases
HAMAP	MF_00122. GatC. Divergent sequence. [Tree]
InterPro	IPR003837. Glu-tRNAGlntrans. [Graphical view]
KO	K02435.
Pfam	PF02686. Glu-tRNAGln. 1 hit. [Graphical view]
TIGRFAMs	TIGR00135. GatC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GATC_BORBU

Accession

Primary (citable) accession number: O51318

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	June 1, 1998
Last modified:	January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program