O51127 (MURI_BORBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	BB_0100

Organism

Borrelia burgdorferi (Lyme disease spirochete)

Taxonomic identifier

139 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 261	261	Glutamate racemase HAMAP MF_00258		PRO_0000095456

Sequences

	Sequence		Length	Mass (Da)
	O51127 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 2EE4C2AD3CE2A237	FASTA	261	30,330
	10 20 30 40 50 60 MKNFKEVIII FDSGIGGLSY FKYIKSRIGG CQYVYVADNK NFPYGEKSPE YLLEAVLFLI 70 80 90 100 110 120 EKLKKIYNIG ALVLACNTIS VSVYNKLNFV FPVVYTLPDV SSVSDLVLKR VLLIATNTTL 130 140 150 160 170 180 ESKFVKDQVN IHNDLIVKAA GELVNFVEYG ENYKKYALRC LEALKFEVVN TGREIVFLGC 190 200 210 220 230 240 THYLHLKVMI EDFLKIPVYE NRELVVKNLI RSMNFSEHKG NYYKNDFDFV DDEFYLTENK 250 260 NLTFYQNFCK KYNLRFKGMI V

References

[1]

"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi." Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. , Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B., Smith H.O., Venter J.C. Nature 390:580-586(1997) [PubMed: 9403685] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000783 Genomic DNA. Translation: AAC66479.1.
PIR	D70112.
RefSeq	NP_212234.1. NC_001318.1.
3D structure databases
ProteinModelPortal	O51127.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000009013; EBBORP00000008343; EBBORG00000009012.
GeneID	1194936.
GenomeReviews	Gene locus BB_0100 in contig AE000783_GR.
KEGG	bbu:BB0100.
NMPDR	fig|224326.1.peg.484.
PATRIC	20556806. VBIBorBur75917_0498.
TIGR	BB_0100.
Phylogenomic databases
GeneTree	EBGT00050000007002.
HOGENOM	HBG645102.
OMA	GCTHYLH.
PhylomeDB	O51127.
ProtClustDB	CLSK507354.
Enzyme and pathway databases
BioCyc	BBUR224326:BB_0100-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 2 hits.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. False negative. PS00924. ASP_GLU_RACEMASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BORBU

Accession

Primary (citable) accession number: O51127

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	June 1, 1998
Last modified:	January 25, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program