Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chemotaxis protein methyltransferase

Gene

cheR

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.By similarity

Catalytic activityi

S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei84S-adenosyl-L-methionineBy similarity1
Binding sitei86S-adenosyl-L-methionineBy similarity1
Binding sitei90S-adenosyl-L-methionineBy similarity1
Binding sitei130S-adenosyl-L-methionineBy similarity1
Binding sitei157S-adenosyl-L-methionineBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Chemotaxis

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis protein methyltransferase (EC:2.1.1.80)
Gene namesi
Name:cheR
Ordered Locus Names:BB_0040
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001760311 – 283Chemotaxis protein methyltransferaseAdd BLAST283

Proteomic databases

PRIDEiO51069.

Interactioni

Protein-protein interaction databases

STRINGi224326.BB_0040.

Structurei

3D structure databases

ProteinModelPortaliO51069.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 283CheR-type methyltransferasePROSITE-ProRule annotationAdd BLAST277

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni212 – 213S-adenosyl-L-methionine bindingBy similarity2
Regioni230 – 231S-adenosyl-L-methionine bindingBy similarity2

Sequence similaritiesi

Contains 1 cheR-type methyltransferase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
KOiK00575.
OMAiFVGHAEN.

Family and domain databases

Gene3Di1.10.155.10. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR026024. Chemotaxis_MeTrfase_CheR.
IPR022642. CheR_C.
IPR000780. CheR_MeTrfase.
IPR022641. CheR_N.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF01739. CheR. 1 hit.
PF03705. CheR_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000410. CheR. 1 hit.
PRINTSiPR00996. CHERMTFRASE.
SMARTiSM00138. MeTrc. 1 hit.
[Graphical view]
SUPFAMiSSF47757. SSF47757. 1 hit.
SSF53335. SSF53335. 1 hit.
PROSITEiPS50123. CHER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O51069-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTNQNKFNL NINITKDELS RLIKIVYNNF GINLSEKKKL LIESRLSSLL
60 70 80 90 100
KVKGFKNFTE YINFLEKSTG NIQLIELIDK ISTNHTYFFR ESKHFDFLNN
110 120 130 140 150
KILPKLTEKI LNSENSEIRI WSAGCSSGEE PYTIAMMLKE YMEHNRVNFK
160 170 180 190 200
VKILATDISI SVLNEAREGI YPEDRIINLP KYLKIKYLNQ LQDDKFQVKE
210 220 230 240 250
ILKKMVYFKK LNLMDEKFPF SKKFDLIFCR NVMIYFDEKT RNNLANKFNS
260 270 280
YLKKDSYLLI GHSETIRGNK NLEYIMPATY KKN
Length:283
Mass (Da):33,560
Last modified:June 1, 1998 - v1
Checksum:i2FF0E4E9C8BC3EEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000783 Genomic DNA. Translation: AAC66439.1.
PIRiH70104.
RefSeqiNP_212174.1. NC_001318.1.
WP_002665509.1. NC_001318.1.

Genome annotation databases

EnsemblBacteriaiAAC66439; AAC66439; BB_0040.
GeneIDi1194876.
KEGGibbu:BB_0040.
PATRICi20556685. VBIBorBur75917_0439.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000783 Genomic DNA. Translation: AAC66439.1.
PIRiH70104.
RefSeqiNP_212174.1. NC_001318.1.
WP_002665509.1. NC_001318.1.

3D structure databases

ProteinModelPortaliO51069.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224326.BB_0040.

Proteomic databases

PRIDEiO51069.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC66439; AAC66439; BB_0040.
GeneIDi1194876.
KEGGibbu:BB_0040.
PATRICi20556685. VBIBorBur75917_0439.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
KOiK00575.
OMAiFVGHAEN.

Family and domain databases

Gene3Di1.10.155.10. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR026024. Chemotaxis_MeTrfase_CheR.
IPR022642. CheR_C.
IPR000780. CheR_MeTrfase.
IPR022641. CheR_N.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF01739. CheR. 1 hit.
PF03705. CheR_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000410. CheR. 1 hit.
PRINTSiPR00996. CHERMTFRASE.
SMARTiSM00138. MeTrc. 1 hit.
[Graphical view]
SUPFAMiSSF47757. SSF47757. 1 hit.
SSF53335. SSF53335. 1 hit.
PROSITEiPS50123. CHER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCHER_BORBU
AccessioniPrimary (citable) accession number: O51069
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.