O50977 (ACYP_BORBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	BB_B01

Encoded on

Plasmid cp26

Organism

Borrelia burgdorferi (Lyme disease spirochete)

Taxonomic identifier

139 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.
Sequence caution	The sequence AAC66325.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Plasmid Reference proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Acylphosphatase HAMAP MF_01450		PRO_0000326664
Regions
	Domain	3 – 92	90	Acylphosphatase-like
Sites
	Active site	18	1	By similarity
	Active site	36	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	O50977 [UniParc]. Last modified April 8, 2008. Version 2. Checksum: 9498E85D560DA607	FASTA	92	11,043
	10 20 30 40 50 60 MYKQQYFISG KVQGVGFRFF TEQIANNMKL KGFVKNLNDG RVEIVAFFNT KEQMKKFEKL 70 80 90 LNGNKYSNIK NIEKIVLDEN YPFQFNDFKI YY

References

[1]

"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi." Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. , Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B., Smith H.O., Venter J.C. Nature 390:580-586(1997) [PubMed: 9403685] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000792 Genomic DNA. Translation: AAC66325.1. Different initiation.
PIR	E70216.
RefSeq	NP_046987.1. NC_001903.1.
3D structure databases
HSSP	HSSP built from PDB template 1Y9O based on UniProtKB Q97ZL0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000009602; EBBORP00000008889; EBBORG00000009601.
GeneID	1194411.
GenomeReviews	Gene locus BB_B01 in contig AE000792_GR.
KEGG	bbu:BBB01.
NMPDR	fig|224326.1.peg.1601.
PATRIC	20559071. VBIBorBur75917_1590.
TIGR	BB_B01.
Phylogenomic databases
GeneTree	EBGT00050000006877.
HOGENOM	HBG750266.
OMA	LFRRIME.
ProtClustDB	PRK14432.
Enzyme and pathway databases
BioCyc	BBUR224326:BB_B01-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_BORBU

Accession

Primary (citable) accession number: O50977

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 68 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program