ID   O50957_BORBU            Unreviewed;       251 AA.
AC   O50957; Q7AUV9;
DT   01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT   01-JUN-1998, sequence version 1.
DT   27-MAR-2024, entry version 129.
DE   SubName: Full=Complement regulator-acquiring surface protein 1 (CRASP-1) {ECO:0000313|EMBL:AAC66286.1};
GN   Name=cspA {ECO:0000313|EMBL:AAC66286.1};
GN   OrderedLocusNames=BB_A68 {ECO:0000313|EMBL:AAC66286.1};
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OG   Plasmid lp54 {ECO:0000313|EMBL:AAC66286.1,
OG   ECO:0000313|Proteomes:UP000001807}.
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC   Borreliella.
OX   NCBI_TaxID=224326 {ECO:0000313|EMBL:AAC66286.1, ECO:0000313|Proteomes:UP000001807};
RN   [1] {ECO:0000313|EMBL:AAC66286.1, ECO:0000313|Proteomes:UP000001807}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / B31 / CIP 102532 / DSM 4680
RC   {ECO:0000313|Proteomes:UP000001807};
RC   PLASMID=Plasmid lp54 {ECO:0000313|Proteomes:UP000001807};
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R., Lathigra R.,
RA   White O., Ketchum K.A., Dodson R., Hickey E.K., Gwinn M., Dougherty B.,
RA   Tomb J.F., Fleischmann R.D., Richardson D., Peterson J., Kerlavage A.R.,
RA   Quackenbush J., Salzberg S., Hanson M., van Vugt R., Palmer N., Adams M.D.,
RA   Gocayne J., Weidman J., Utterback T., Watthey L., McDonald L., Artiach P.,
RA   Bowman C., Garland S., Fuji C., Cotton M.D., Horst K., Roberts K.,
RA   Hatch B., Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
RN   [2] {ECO:0007829|PDB:1W33, ECO:0007829|PDB:1W3Z}
RP   X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 70-250.
RX   PubMed=15711564; DOI=10.1038/nsmb902;
RA   Cordes F.S., Roversi P., Kraiczy P., Simon M.M., Brade V., Jahraus O.,
RA   Wallis R., Skerka C., Zipfel P.F., Wallich R., Lea S.M.;
RT   "A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia
RT   burgdorferi.";
RL   Nat. Struct. Mol. Biol. 12:276-277(2005).
RN   [3] {ECO:0007829|PDB:5A2U}
RP   X-RAY CRYSTALLOGRAPHY (3.30 ANGSTROMS) OF 65-251.
RA   Brangulis K., Petrovskis I., Kazaks A., Tars K.;
RT   "Crystal Structure of Bba68 or Bbcrasp-1 from Borrelia Burgdorferi Strain
RT   B31.";
RL   Submitted (MAY-2015) to the PDB data bank.
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DR   EMBL; AE000790; AAC66286.1; -; Genomic_DNA.
DR   PIR; D70215; D70215.
DR   RefSeq; NP_045741.1; NC_001857.2.
DR   RefSeq; WP_010890397.1; NC_001857.2.
DR   PDB; 1W33; X-ray; 2.70 A; A/B=70-250.
DR   PDB; 1W3Z; X-ray; 3.20 A; A/B=70-250.
DR   PDB; 5A2U; X-ray; 3.30 A; A/B=65-251.
DR   PDBsum; 1W33; -.
DR   PDBsum; 1W3Z; -.
DR   PDBsum; 5A2U; -.
DR   AlphaFoldDB; O50957; -.
DR   SMR; O50957; -.
DR   EnsemblBacteria; AAC66286; AAC66286; BB_A68.
DR   KEGG; bbu:BB_A68; -.
DR   PATRIC; fig|224326.49.peg.1581; -.
DR   HOGENOM; CLU_080351_1_0_12; -.
DR   OrthoDB; 352901at2; -.
DR   EvolutionaryTrace; O50957; -.
DR   Proteomes; UP000001807; Plasmid lp54.
DR   Gene3D; 1.10.3160.10; Bbcrasp-1; 1.
DR   InterPro; IPR008421; Borrelia_lipoprotein_PFam54/60.
DR   NCBIfam; NF033729; borfam54_2; 1.
DR   Pfam; PF05714; PFam54_60; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:1W33, ECO:0007829|PDB:1W3Z};
KW   Coiled coil {ECO:0000256|SAM:Coils}; Plasmid {ECO:0000313|EMBL:AAC66286.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001807};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..251
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004159566"
FT   REGION          36..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          69..100
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        39..58
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   251 AA;  29173 MW;  827180603D783E3F CRC64;
     MKKAKLNIIK INIIAMILTL ICTSCAPFSK IDPKANANTK PKKITNPGEN TQNFEDKSGD
     LSTSDEKIME TIASELKAIG KELEDQKKEE NIQIAKIAKE KFDFLSTFKV GPYDLIDEDI
     QMKIKRTLYS SLDYKKENIE KLKEILEILK KNSEHYNIIG RLIYHISWGI QFQIEQNLEL
     IQNGVENLSQ EESKSLLMQI KSNLEIKQRL KKTLNETLKV YNQNTQDNEK ILAEHFNKYY
     KDFDTLKPAF Y
//