SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O50917

- DBPA_BORBU

UniProt

O50917 - DBPA_BORBU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Decorin-binding protein A
Gene
dbpA, BB_A24
Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.

Enzyme and pathway databases

BioCyciBBUR224326:G9SO-884-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Decorin-binding protein A
Gene namesi
Name:dbpA
Ordered Locus Names:BB_A24
Encoded oniPlasmid lp540 Publication
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
ProteomesiUP000001807: Plasmid lp54

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929 Reviewed prediction
Add
BLAST
Chaini30 – 191162Decorin-binding protein A
PRO_0000021074Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224326.BBA24.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni28 – 303
Helixi31 – 5525
Beta strandi72 – 743
Helixi76 – 10328
Turni104 – 1063
Helixi108 – 12922
Helixi134 – 14411
Helixi150 – 17526
Helixi177 – 1804

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2LQUNMR-A24-191[»]

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG148274.
OMAiGEFSAMY.
OrthoDBiEOG6Z0QD4.

Family and domain databases

InterProiIPR003332. Decorin-bd.
[Graphical view]
PfamiPF02352. Decorin_bind. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O50917-1 [UniParc]FASTAAdd to Basket

« Hide

MIKCNNKTFN NLLKLTILVN LLISCGLTGA TKIRLERSAK DITDEIDAIK    50
KDAALKGVNF DAFKDKKTGS GVSENPFILE AKVRATTVAE KFVIAIEEEA 100
TKLKETGSSG EFSAMYDLMF EVSKPLQKLG IQEMTKTVSD AAEENPPTTA 150
QGVLEIAKKM REKLQRVHTK NYCTLKKKEN STFTDEKCKN N 191
Length:191
Mass (Da):21,214
Last modified:June 1, 1998 - v1
Checksum:iAD1F191C774AFEA1
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti34 – 341R → K in strain: 297, LP7 and Sh-2-82.
Natural varianti37 – 371R → S in strain: 297, LP7 and Sh-2-82.
Natural varianti41 – 433DIT → AIV in strain: 297, LP7 and Sh-2-82.
Natural varianti52 – 521D → K in strain: 297, LP7 and Sh-2-82.
Natural varianti55 – 562LK → SM in strain: 297, LP7 and Sh-2-82.
Natural varianti128 – 1281K → E in strain: 297, LP7 and Sh-2-82.
Natural varianti140 – 1401D → M in strain: 297, LP7 and Sh-2-82.
Natural varianti169 – 1691T → K in strain: 297, LP7 and Sh-2-82.
Natural varianti172 – 1732YC → QD in strain: 297, LP7 and Sh-2-82.
Natural varianti179 – 19113ENSTF…KCKNN → NTEDSTAKS in strain: 297, LP7 and Sh-2-82.
Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U75866 Genomic DNA. Translation: AAD05353.1.
AF069253 Genomic DNA. Translation: AAC70026.1.
AF069255 Genomic DNA. Translation: AAC70030.1.
AF069257 Genomic DNA. Translation: AAC70034.1.
AF069286 Genomic DNA. Translation: AAC70064.1.
AF069269 Genomic DNA. Translation: AAC70047.1.
AF069275 Genomic DNA. Translation: AAC70053.1.
AE000790 Genomic DNA. Translation: AAC66250.1.
PIRiH70209.
RefSeqiNP_045697.1. NC_001857.2.
WP_010890380.1. NC_001857.2.

Genome annotation databases

EnsemblBacteriaiAAC66250; AAC66250; BB_A24.
GeneIDi1194347.
KEGGibbu:BB_A24.
PATRICi20558972. VBIBorBur75917_1541.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U75866 Genomic DNA. Translation: AAD05353.1 .
AF069253 Genomic DNA. Translation: AAC70026.1 .
AF069255 Genomic DNA. Translation: AAC70030.1 .
AF069257 Genomic DNA. Translation: AAC70034.1 .
AF069286 Genomic DNA. Translation: AAC70064.1 .
AF069269 Genomic DNA. Translation: AAC70047.1 .
AF069275 Genomic DNA. Translation: AAC70053.1 .
AE000790 Genomic DNA. Translation: AAC66250.1 .
PIRi H70209.
RefSeqi NP_045697.1. NC_001857.2.
WP_010890380.1. NC_001857.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2LQU NMR - A 24-191 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224326.BBA24.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC66250 ; AAC66250 ; BB_A24 .
GeneIDi 1194347.
KEGGi bbu:BB_A24.
PATRICi 20558972. VBIBorBur75917_1541.

Phylogenomic databases

eggNOGi NOG148274.
OMAi GEFSAMY.
OrthoDBi EOG6Z0QD4.

Enzyme and pathway databases

BioCyci BBUR224326:G9SO-884-MONOMER.

Family and domain databases

InterProi IPR003332. Decorin-bd.
[Graphical view ]
Pfami PF02352. Decorin_bind. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Adherence of Borrelia burgdorferi to the proteoglycan decorin."
    Guo B.P., Norris S.J., Rosenberg L.C., Hook M.
    Infect. Immun. 63:3467-3472(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 53899 / 297.
  2. "Molecular analysis of sequence heterogeneity among genes encoding decorin binding proteins A and B of Borrelia burgdorferi sensu lato."
    Roberts W.C., Mullikin B.A., Lathigra R., Hanson M.S.
    Infect. Immun. 66:5275-5285(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 3028, ATCC 35210 / B31 / CIP 102532 / DSM 4680, HBNC, LP7 and Sh-2-82.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Entry informationi

Entry nameiDBPA_BORBU
AccessioniPrimary (citable) accession number: O50917
Secondary accession number(s): O06876, Q9R8Q5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: June 1, 1998
Last modified: September 3, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Plasmid, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi