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Protein

Decorin-binding protein A

Gene

dbpA

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.

Names & Taxonomyi

Protein namesi
Recommended name:
Decorin-binding protein A
Gene namesi
Name:dbpA
Ordered Locus Names:BB_A24
Encoded oniPlasmid lp540 Publication
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Plasmid lp54

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000002107430 – 191Decorin-binding protein AAdd BLAST162

Proteomic databases

PRIDEiO50917.

Structurei

Secondary structure

1191
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni28 – 30Combined sources3
Helixi31 – 55Combined sources25
Beta strandi72 – 74Combined sources3
Helixi76 – 103Combined sources28
Turni104 – 106Combined sources3
Helixi108 – 129Combined sources22
Helixi134 – 144Combined sources11
Helixi150 – 175Combined sources26
Helixi177 – 180Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2LQUNMR-A24-191[»]
ProteinModelPortaliO50917.
SMRiO50917.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the decorin-binding protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

OMAiGEFSAMY.

Family and domain databases

InterProiIPR003332. Decorin-bd.
[Graphical view]
PfamiPF02352. Decorin_bind. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O50917-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKCNNKTFN NLLKLTILVN LLISCGLTGA TKIRLERSAK DITDEIDAIK
60 70 80 90 100
KDAALKGVNF DAFKDKKTGS GVSENPFILE AKVRATTVAE KFVIAIEEEA
110 120 130 140 150
TKLKETGSSG EFSAMYDLMF EVSKPLQKLG IQEMTKTVSD AAEENPPTTA
160 170 180 190
QGVLEIAKKM REKLQRVHTK NYCTLKKKEN STFTDEKCKN N
Length:191
Mass (Da):21,214
Last modified:June 1, 1998 - v1
Checksum:iAD1F191C774AFEA1
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti34R → K in strain: 297, LP7 and Sh-2-82. 1
Natural varianti37R → S in strain: 297, LP7 and Sh-2-82. 1
Natural varianti41 – 43DIT → AIV in strain: 297, LP7 and Sh-2-82. 3
Natural varianti52D → K in strain: 297, LP7 and Sh-2-82. 1
Natural varianti55 – 56LK → SM in strain: 297, LP7 and Sh-2-82. 2
Natural varianti128K → E in strain: 297, LP7 and Sh-2-82. 1
Natural varianti140D → M in strain: 297, LP7 and Sh-2-82. 1
Natural varianti169T → K in strain: 297, LP7 and Sh-2-82. 1
Natural varianti172 – 173YC → QD in strain: 297, LP7 and Sh-2-82. 2
Natural varianti179 – 191ENSTF…KCKNN → NTEDSTAKS in strain: 297, LP7 and Sh-2-82. Add BLAST13

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75866 Genomic DNA. Translation: AAD05353.1.
AF069253 Genomic DNA. Translation: AAC70026.1.
AF069255 Genomic DNA. Translation: AAC70030.1.
AF069257 Genomic DNA. Translation: AAC70034.1.
AF069286 Genomic DNA. Translation: AAC70064.1.
AF069269 Genomic DNA. Translation: AAC70047.1.
AF069275 Genomic DNA. Translation: AAC70053.1.
AE000790 Genomic DNA. Translation: AAC66250.1.
PIRiH70209.
RefSeqiNP_045697.1. NC_001857.2.
WP_010890380.1. NC_001857.2.

Genome annotation databases

EnsemblBacteriaiAAC66250; AAC66250; BB_A24.
GeneIDi1194347.
KEGGibbu:BB_A24.
PATRICi20558972. VBIBorBur75917_1541.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75866 Genomic DNA. Translation: AAD05353.1.
AF069253 Genomic DNA. Translation: AAC70026.1.
AF069255 Genomic DNA. Translation: AAC70030.1.
AF069257 Genomic DNA. Translation: AAC70034.1.
AF069286 Genomic DNA. Translation: AAC70064.1.
AF069269 Genomic DNA. Translation: AAC70047.1.
AF069275 Genomic DNA. Translation: AAC70053.1.
AE000790 Genomic DNA. Translation: AAC66250.1.
PIRiH70209.
RefSeqiNP_045697.1. NC_001857.2.
WP_010890380.1. NC_001857.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2LQUNMR-A24-191[»]
ProteinModelPortaliO50917.
SMRiO50917.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiO50917.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC66250; AAC66250; BB_A24.
GeneIDi1194347.
KEGGibbu:BB_A24.
PATRICi20558972. VBIBorBur75917_1541.

Phylogenomic databases

OMAiGEFSAMY.

Family and domain databases

InterProiIPR003332. Decorin-bd.
[Graphical view]
PfamiPF02352. Decorin_bind. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDBPA_BORBU
AccessioniPrimary (citable) accession number: O50917
Secondary accession number(s): O06876, Q9R8Q5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: June 1, 1998
Last modified: November 2, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Plasmid, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.