Skip Header

Contribute Send feedback
Read comments (?) or add your own

O50821 (ADEC_BORBU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Adenine deaminase
Short name=Adenase
Short name=Adenine aminase
EC=3.5.4.2
Gene names
Name:ade
Ordered Locus Names:BB_K17
Encoded onPlasmid lp36
OrganismBorrelia burgdorferi (Lyme disease spirochete)
Taxonomic identifier139 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518

Cofactor

Manganese By similarity. HAMAP MF_01518

Sequence similarities

Belongs to the adenine deaminase family.

Ontologies

Keywords
   LigandManganese
   Molecular functionHydrolase
   Technical termComplete proteome
Plasmid
Reference proteome
Gene Ontology (GO)
   Biological processadenine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionadenine deaminase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 548548Adenine deaminase HAMAP MF_01518
PRO_0000142406

Sequences

Sequence LengthMass (Da)Tools
O50821 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 012AE5222AD8301E

FASTA54860,864
        10         20         30         40         50         60 
MDLFKIEANY IDIFNKEIYP ASIAIANGHI ASIEKINATL DEYVLPGFID AHIHIESSFL 

        70         80         90        100        110        120 
VPSNFAHLVV AHGTVATISD PHEIANVNGI DGINFMINNS KKTEFKFFFG APSCVPALSQ 

       130        140        150        160        170        180 
EFETSGYVLN DKDIDELMKL DDIYYLAEVM DFKGVINKDI EIINKINSAL KRNKVVDGHA 

       190        200        210        220        230        240 
PGLSPNLTLK YASSGISTDH ECLTIEDARY KLSLGMKILI REGSAAKNFE SLHPLISECS 

       250        260        270        280        290        300 
KKYCDSLMFC FDDAHPNDIL NGHINLIVAR AIKHGHDFFD VLKIACINPV LHYKIPVGLL 

       310        320        330        340        350        360 
RIGDPADFII TKDIKTFKIN KTYINGKLVF NDGISLIPLI NEIPINNFNC SKKSISDFKF 

       370        380        390        400        410        420 
STKNKMIPVI KCISNQIITH KTMIDSNLLA PDFQSNIAED ILKIAIINRY KDNSKISIGF 

       430        440        450        460        470        480 
IKNFGIRNGA IGSTVAHDSH NIILVGSNDE YLCKAANTII QNKGGLCALN NEKTIIMELP 

       490        500        510        520        530        540 
ISGLMSTLSA ERVASQYIKL NDFCKNVLGS RLDDPLMTLS FMSLTVVPHL KINDKGLFDV 


DSFCFVDY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000788 Genomic DNA. Translation: AAC66139.1.
PIRC70253.
RefSeqNP_045591.1. NC_001855.1.

3D structure databases

ProteinModelPortalO50821.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBORT00000009408; EBBORP00000008696; EBBORG00000009407.
GeneID1194225.
GenomeReviewsGene locus BB_K17 in contig AE000788_GR.
KEGGbbu:BBK17.
NMPDRfig|224326.1.peg.1442.
PATRIC20558762. VBIBorBur75917_1437.
TIGRBB_K17.

Phylogenomic databases

GeneTreeEBGT00050000006788.
HOGENOMHBG725357.
OMAVGLGEMM.
PhylomeDBO50821.
ProtClustDBCLSK862557.

Enzyme and pathway databases

BioCycBBUR224326:BB_K17-MONOMER.

Family and domain databases

HAMAPMF_01518. Adenine_deamin.
[Tree]
InterProIPR006679. Adenine_deam.
IPR006680. Amidohydro_1.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR01178. Ade. 1 hit.
ProtoNetSearch...

Entry information

Entry nameADEC_BORBU
AccessionPrimary (citable) accession number: O50821
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents