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Protein

Transporter

Gene

tnaT

Organism
Symbiobacterium thermophilum
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

SymportUniRule annotation, Transport

Protein family/group databases

TCDBi2.A.22.4.1. the neurotransmitter:sodium symporter (nss) family.

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:tnaTImported
OrganismiSymbiobacterium thermophilumImported
Taxonomic identifieri2734 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSymbiobacteriaceaeSymbiobacterium

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3120HelicalSequence analysisAdd
BLAST
Transmembranei43 – 6523HelicalSequence analysisAdd
BLAST
Transmembranei86 – 10823HelicalSequence analysisAdd
BLAST
Transmembranei146 – 16419HelicalSequence analysisAdd
BLAST
Transmembranei184 – 20522HelicalSequence analysisAdd
BLAST
Transmembranei225 – 24622HelicalSequence analysisAdd
BLAST
Transmembranei258 – 28427HelicalSequence analysisAdd
BLAST
Transmembranei317 – 33923HelicalSequence analysisAdd
BLAST
Transmembranei360 – 38425HelicalSequence analysisAdd
BLAST
Transmembranei390 – 41021HelicalSequence analysisAdd
BLAST
Transmembranei430 – 44920HelicalSequence analysisAdd
BLAST
Transmembranei461 – 48525HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi292459.STH442.

Structurei

3D structure databases

ProteinModelPortaliO50649.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105C8J. Bacteria.
COG0733. LUCA.
HOGENOMiHOG000033130.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 2 hits.
PfamiPF00209. SNF. 2 hits.
[Graphical view]
PRINTSiPR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O50649-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAQRDQWKS RSGFIFATIG AAVGLGNFWR FPFMAYQNGG GAFLLPYFVA
60 70 80 90 100
LLTAGVPLMI LEFGFGHKMR TATITAFKKL NRRFEWIGWW QITVPVVVVT
110 120 130 140 150
FYSVIISWSL RYLIFSFTQA WGDDPGTFFS SDFLGITSGP LELGGLRWGI
160 170 180 190 200
FAAVAVVWFA NYYISAQGIS GGIEKACKIM TPFLIVAMLI FVIRGITLPG
210 220 230 240 250
ATYGLNYFLN PDFSKIMDPG VWVAAYSQVF FSTTLAVGVM IAYASYVPED
260 270 280 290 300
SDLANNAFIT VFANSSFDFM AGLAVFSTLG YAAVTAGVPF EEMAVAGPGV
310 320 330 340 350
AFVAFPKAIS MLPGPTWLQS LFGILFFSAL LLAGISSSIS QMESFASAVI
360 370 380 390 400
DRFGVDRKKL LGWFSLIGFA FSALFATGAG VHILDIVDHF VGSYAIAILG
410 420 430 440 450
LVEAIVLGYI MGTARIREHV NLTSDIRVGM WWDVLVKYVT PVLLGYNILS
460 470 480 490 500
NFISEFREPY AGYPTGALVL FGWVVAIAMF GTSLFMQWRS QQLDVTGGEV

G
Length:501
Mass (Da):54,750
Last modified:October 1, 2002 - v2
Checksum:iEEF0703FE26CF5DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010832 Genomic DNA. Translation: BAA24689.2.

Genome annotation databases

PATRICi23778958. VBISymThe116959_0426.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010832 Genomic DNA. Translation: BAA24689.2.

3D structure databases

ProteinModelPortaliO50649.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292459.STH442.

Protein family/group databases

TCDBi2.A.22.4.1. the neurotransmitter:sodium symporter (nss) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

PATRICi23778958. VBISymThe116959_0426.

Phylogenomic databases

eggNOGiENOG4105C8J. Bacteria.
COG0733. LUCA.
HOGENOMiHOG000033130.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 2 hits.
PfamiPF00209. SNF. 2 hits.
[Graphical view]
PRINTSiPR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning, nucleotide sequences, and overexpression in Escherichia coli of tandem copies of a tryptophanase gene in an obligately symbiotic thermophile, Symbiobacterium thermophilum."
    Hirahara T., Suzuki S., Horinouchi S., Beppu T.
    Appl. Environ. Microbiol. 58:2633-2642(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Tryptophanase operon of Symbiobacterium thermophilum."
    Beppu T., Ueda K.
    Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO50649_SYMTR
AccessioniPrimary (citable) accession number: O50649
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: October 1, 2002
Last modified: March 16, 2016
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.