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Protein

Alpha-amylase

Gene
N/A
Organism
Streptococcus equinus (Streptococcus bovis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Protein family/group databases

CAZyiCBM26. Carbohydrate-Binding Module Family 26.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
OrganismiStreptococcus equinus (Streptococcus bovis)Imported
Taxonomic identifieri1335 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3939Sequence analysisAdd
BLAST
Chaini40 – 742703Alpha-amylaseSequence analysisPRO_5004158847Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi525379.HMPREF0819_0979.

Structurei

3D structure databases

ProteinModelPortaliO50582.
SMRiO50582. Positions 44-463.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 380333AamyInterPro annotationAdd
BLAST
Domaini390 – 46576Aamy_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR031965. CBM26.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF16738. CBM26. 2 hits.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

O50582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFQNKVNLK KKMKKSLGSL LILTAIGAGG LVQVKVVNAD EQVSMKDGTI
60 70 80 90 100
LHAWCWSFNT IKDNMQAIKD AGYTSVQTSP INTVVAGEGG NKSLKNWYYQ
110 120 130 140 150
YQPTIYKIGN YQLGTEEEFK EMNRVADQYG IKIIVDAVLN HTTSDYNQIS
160 170 180 190 200
QEIKNIPNWT HGNTLISDWH NRYDVTQNAL LTLYDWNTQN EYVQQYLLSY
210 220 230 240 250
LKQAVADGAD GFRYDAAKHI ELPGEYGSNF WNVILNNGSE FQYGEILQDD
260 270 280 290 300
VSNDAGYGKL MSITASNYGQ KIRSALKDRH ISAGNLMNYQ VSGVDAANLV
310 320 330 340 350
TWVESHDNYA NDDQESTWMN DSDIGLGWAM ITARAKGTPL FFSRPVGGGN
360 370 380 390 400
GTRFPGQSQI GDAGSNLYKD ATVTAVNKFH NAMVGESEYL RNPGGDEQVA
410 420 430 440 450
MIERGTKGAV IVNLVDGDKQ INSETNLADG TYTDKVSGRQ FNVSNGRITG
460 470 480 490 500
SVPSRSAVVL YDDQASQAAQ VSVDGYKEGD NSISKATEVT LKAKNADSAT
510 520 530 540 550
YKLGNGQEVA YKDGDKVTVG EGLEAGQSTT LTLTATGADG QSTTKTYTFT
560 570 580 590 600
MKDPSAETNI YFQNPDNWSE VYAYMYSAKD NKLLGAWPGT KMTKEASGRY
610 620 630 640 650
SITVPASYAE EGVKVIFTNN QGSQYPQNEG FDFKAEGLYS KAGLMPDVPA
660 670 680 690 700
GKTRVTFDNP GGWDSANAYL YYGNPVQYPL GVWPGTQMTK DDAGNFYLDL
710 720 730 740
PEEYADVNAK IIFNQPGTSN QYPYSEGFNL VKSGNYNKDG LK
Length:742
Mass (Da):81,465
Last modified:June 1, 1998 - v1
Checksum:i95560FB5D90E8359
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000829 Genomic DNA. Translation: BAA24177.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000829 Genomic DNA. Translation: BAA24177.1.

3D structure databases

ProteinModelPortaliO50582.
SMRiO50582. Positions 44-463.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi525379.HMPREF0819_0979.

Protein family/group databases

CAZyiCBM26. Carbohydrate-Binding Module Family 26.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR031965. CBM26.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF16738. CBM26. 2 hits.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Purification, characterization, and nucleotide sequence of an intracellular maltotriose-producing alpha-amylase from Streptococcus bovis 148."
    Satoh E., Uchimura T., Kudo T., Komagata K.
    Appl. Environ. Microbiol. 63:4941-4944(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 148Imported.

Entry informationi

Entry nameiO50582_STREI
AccessioniPrimary (citable) accession number: O50582
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.