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O50258 (NLR_DESGI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Neelaredoxin

EC=1.15.1.1
Alternative name(s):
Superoxide dismutase
Gene names
Name:nlr
OrganismDesulfovibrio gigas
Taxonomic identifier879 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

Protein attributes

Sequence length130 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Non-heme iron protein.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 2 iron ions per subunit.

Subunit structure

Monomer.

Miscellaneous

Has a reduction potential of +190 mV.

Sequence similarities

Belongs to the desulfoferrodoxin family.

Ontologies

Keywords
   Biological processElectron transport
Transport
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Molecular_functioniron ion binding

Inferred from electronic annotation. Source: InterPro

superoxide dismutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 130130Neelaredoxin
PRO_0000140869

Sites

Metal binding151Iron By similarity
Metal binding171Iron By similarity
Metal binding451Iron By similarity
Metal binding511Iron By similarity
Metal binding1151Iron By similarity
Metal binding1181Iron By similarity

Experimental info

Sequence conflict41C → Y AA sequence Ref.3

Sequences

Sequence LengthMass (Da)Tools
O50258 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: F0B8E1262CDA4180

FASTA13014,523
        10         20         30         40         50         60 
MKMCDMFQTA DWKTEKHVPA IECDDAVAAD AFFPVTVSLG KEIAHPNTTE HHIRWIRCYF 

        70         80         90        100        110        120 
KPEGDKFSYE VGSFEFTAHG ECAKGPNEGP VYTNHTVTFQ LKIKTPGVLV ASSFCNIHGL 

       130 
WESSKAVALK 

« Hide

References

[1]Shenvi N.V., Kurtz D.M. Jr.
Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Desulfovibrio gigas neelaredoxin. A novel superoxide dismutase integrated in a putative oxygen sensory operon of an anaerobe."
Silva G., Oliveira S., Gomes C.M., Pacheco I., Liu M.Y., Xavier A.V., Teixeira M., LeGall J., Rodrigues-Pousada C.
Eur. J. Biochem. 259:235-243(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
Strain: ATCC 19364 / DSM 1382 / NCIB 9332 / VKM B-1759.
[3]"A blue non-heme iron protein from Desulfovibrio gigas."
Chen L., Sharma P., le Gall J., Mariano A.M., Teixeira M., Xavier A.V.
Eur. J. Biochem. 226:613-618(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-28.
Strain: ATCC 19364 / DSM 1382 / NCIB 9332 / VKM B-1759.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF034965 Genomic DNA. Translation: AAB87989.1.
AF096317 Genomic DNA. Translation: AAD13200.1.

3D structure databases

ProteinModelPortalO50258.
SMRO50258. Positions 1-130.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR002742. Desulfoferrodoxin_Fe-bd_dom.
[Graphical view]
PfamPF01880. Desulfoferrodox. 1 hit.
[Graphical view]
SUPFAMSSF49367. SSF49367. 1 hit.
TIGRFAMsTIGR00332. neela_ferrous. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNLR_DESGI
AccessionPrimary (citable) accession number: O50258
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: October 16, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families