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O50258

- NLR_DESGI

UniProt

O50258 - NLR_DESGI

Protein

Neelaredoxin

Gene

nlr

Organism
Desulfovibrio gigas
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Non-heme iron protein.

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.

    Cofactori

    Binds 2 iron ions per subunit.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi15 – 151IronBy similarity
    Metal bindingi17 – 171IronBy similarity
    Metal bindingi45 – 451IronBy similarity
    Metal bindingi51 – 511IronBy similarity
    Metal bindingi115 – 1151IronBy similarity
    Metal bindingi118 – 1181IronBy similarity

    GO - Molecular functioni

    1. iron ion binding Source: InterPro
    2. superoxide dismutase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Neelaredoxin (EC:1.15.1.1)
    Alternative name(s):
    Superoxide dismutase
    Gene namesi
    Name:nlr
    OrganismiDesulfovibrio gigas
    Taxonomic identifieri879 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 130130NeelaredoxinPRO_0000140869Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.

    Structurei

    3D structure databases

    ProteinModelPortaliO50258.
    SMRiO50258. Positions 1-130.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the desulfoferrodoxin family.Curated

    Family and domain databases

    InterProiIPR002742. Desulfoferrodoxin_Fe-bd_dom.
    [Graphical view]
    PfamiPF01880. Desulfoferrodox. 1 hit.
    [Graphical view]
    SUPFAMiSSF49367. SSF49367. 1 hit.
    TIGRFAMsiTIGR00332. neela_ferrous. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O50258-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKMCDMFQTA DWKTEKHVPA IECDDAVAAD AFFPVTVSLG KEIAHPNTTE    50
    HHIRWIRCYF KPEGDKFSYE VGSFEFTAHG ECAKGPNEGP VYTNHTVTFQ 100
    LKIKTPGVLV ASSFCNIHGL WESSKAVALK 130
    Length:130
    Mass (Da):14,523
    Last modified:June 1, 1998 - v1
    Checksum:iF0B8E1262CDA4180
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti4 – 41C → Y AA sequence (PubMed:8001576)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF034965 Genomic DNA. Translation: AAB87989.1.
    AF096317 Genomic DNA. Translation: AAD13200.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF034965 Genomic DNA. Translation: AAB87989.1 .
    AF096317 Genomic DNA. Translation: AAD13200.1 .

    3D structure databases

    ProteinModelPortali O50258.
    SMRi O50258. Positions 1-130.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR002742. Desulfoferrodoxin_Fe-bd_dom.
    [Graphical view ]
    Pfami PF01880. Desulfoferrodox. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49367. SSF49367. 1 hit.
    TIGRFAMsi TIGR00332. neela_ferrous. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Shenvi N.V., Kurtz D.M. Jr.
      Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Desulfovibrio gigas neelaredoxin. A novel superoxide dismutase integrated in a putative oxygen sensory operon of an anaerobe."
      Silva G., Oliveira S., Gomes C.M., Pacheco I., Liu M.Y., Xavier A.V., Teixeira M., LeGall J., Rodrigues-Pousada C.
      Eur. J. Biochem. 259:235-243(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
      Strain: ATCC 19364 / DSM 1382 / NCIB 9332 / VKM B-1759.
    3. Cited for: PROTEIN SEQUENCE OF 1-28.
      Strain: ATCC 19364 / DSM 1382 / NCIB 9332 / VKM B-1759.

    Entry informationi

    Entry nameiNLR_DESGI
    AccessioniPrimary (citable) accession number: O50258
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: June 1, 1998
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Has a reduction potential of +190 mV.

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3