Reviewed,
UniProtKB/Swiss-Prot O50174 (ASTD_PSEAE)
Last modified
November 25, 2008.
Version 61.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: N-succinylglutamate 5-semialdehyde dehydrogenase EC=1.2.1.71 Alternative name(s): Succinylglutamic semialdehyde dehydrogenase Short name=SGSD | ||||||
| Gene names |
| ||||||
| Organism | Pseudomonas aeruginosa [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 287 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas |
Protein attributes
| Sequence length | 487 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. |
| Catalytic activity | N-succinyl-L-glutamate 5-semialdehyde + NAD(+) + H(2)O = N-succinyl-L-glutamate + NADH. |
| Pathway | |
| Induction | By arginine, under the control of argR. |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. AstD subfamily. |
Ontologies
Keywords | |
|---|---|
| Biological process | Arginine metabolism |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | arginine catabolic process to glutamate Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | succinylglutamate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa." Itoh Y. J. Bacteriol. 179:7280-7290(1997) [PubMed: 9393691] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION, PATHWAY. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228. |
| [2] | "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. Olson M.V.Nature 406:959-964(2000) [PubMed: 10984043] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228. |
Cross-references
Sequence databases | |
|---|---|
| AF011922 Genomic DNA. Translation: AAC46012.1. Different initiation. AE004091 Genomic DNA. Translation: AAG04287.1. Different initiation. | |
| PIR | C83533. |
| RefSeq | NP_249589.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 883040. |
| GenomeReviews | Gene locus PA0898 in contig AE004091_GR. |
| KEGG | pae:PA0898. |
| NMPDR | fig|208964.1.peg.899. |
Organism-specific databases | |
| PseudoCAP | PA0898. |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | O50174. |
Enzyme and pathway databases | |
| BioCyc | PAER208964:PA0898-MON. |
Family and domain databases | |
| HAMAP | MF_01174. [Tree] |
| InterPro | IPR016160. Ald_DHase_CS. IPR015590. Aldehyde_DHase. IPR017649. SuccinylGlu_semiald_DH_AstD. [Graphical view] |
| PANTHER | PTHR11699. Aldehyde_dehyd. 1 hit. |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ASTD_PSEAE | ||||||||
| Accession | Primary (citable) accession number: O50174 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


