Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O50152

- O50152_STRGR

UniProt

O50152 - O50152_STRGR

Protein
Submitted name:

Chitinase C

Gene

chiC

Organism
Streptomyces griseus
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Jun 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei105 – 1051Chloride 1
    Binding sitei111 – 1111Chloride 1; via amide nitrogen
    Binding sitei123 – 1231Chloride 2; via amide nitrogen
    Active sitei147 – 1471Proton donor/acceptorImported
    Active sitei156 – 1561Proton donor/acceptorImported
    Binding sitei178 – 1781Chloride 4; via amide nitrogen
    Sitei194 – 1941Transition state stabilizerImported

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. chitinase activity Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. cell wall macromolecule catabolic process Source: InterPro
    3. chitin catabolic process Source: InterPro

    Protein family/group databases

    CAZyiCBM5. Carbohydrate-Binding Module Family 5.
    GH19. Glycoside Hydrolase Family 19.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Chitinase CImported
    Gene namesi
    Name:chiCImported
    OrganismiStreptomyces griseusImported
    Taxonomic identifieri1911 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1WVUX-ray2.45A/B30-294[»]
    1WVVX-ray2.00A/B30-294[»]
    2D49NMR-A30-82[»]
    2DBTX-ray3.14A/B/C30-294[»]
    ProteinModelPortaliO50152.
    SMRiO50152. Positions 30-81, 86-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiO50152.

    Family & Domainsi

    Family and domain databases

    Gene3Di2.10.10.20. 1 hit.
    InterProiIPR003610. CBM_fam5/12.
    IPR016283. Glyco_hydro_19.
    IPR000726. Glyco_hydro_19_cat.
    IPR023346. Lysozyme-like_dom.
    [Graphical view]
    PfamiPF02839. CBM_5_12. 1 hit.
    PF00182. Glyco_hydro_19. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001060. Endochitinase. 1 hit.
    SMARTiSM00495. ChtBD3. 1 hit.
    [Graphical view]
    SUPFAMiSSF51055. SSF51055. 1 hit.
    SSF53955. SSF53955. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O50152-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYRRVMSLLV ALGAIVAALI VLPATTAQAA TCATAWSSSS VYTNGGTVSY    50
    NGRNYTAKWW TQNERPGTSD VWADKGACGT GGEGPGGNNG FVVSEAQFNQ 100
    MFPNRNAFYT YKGLTDALSA YPAFAKTGSD EVKKREAAAF LANVSHETGG 150
    LFYIKEVNEA NYPHYCDTTQ SYGCPAGQAA YYGRGPIQLS WNFNYKAAGD 200
    ALGINLLANP YLVEQDPAVA WKTGLWYWNS QNGPGTMTPH NAIVNNAGFG 250
    ETIRSINGAL ECNGGNPAQV QSRINKFTQF TQILGTTTGP NLSC 294
    Length:294
    Mass (Da):31,473
    Last modified:June 1, 1998 - v1
    Checksum:i21B674EC35662634
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB009289 Genomic DNA. Translation: BAA23739.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB009289 Genomic DNA. Translation: BAA23739.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1WVU X-ray 2.45 A/B 30-294 [» ]
    1WVV X-ray 2.00 A/B 30-294 [» ]
    2D49 NMR - A 30-82 [» ]
    2DBT X-ray 3.14 A/B/C 30-294 [» ]
    ProteinModelPortali O50152.
    SMRi O50152. Positions 30-81, 86-294.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM5. Carbohydrate-Binding Module Family 5.
    GH19. Glycoside Hydrolase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei O50152.

    Family and domain databases

    Gene3Di 2.10.10.20. 1 hit.
    InterProi IPR003610. CBM_fam5/12.
    IPR016283. Glyco_hydro_19.
    IPR000726. Glyco_hydro_19_cat.
    IPR023346. Lysozyme-like_dom.
    [Graphical view ]
    Pfami PF02839. CBM_5_12. 1 hit.
    PF00182. Glyco_hydro_19. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001060. Endochitinase. 1 hit.
    SMARTi SM00495. ChtBD3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51055. SSF51055. 1 hit.
    SSF53955. SSF53955. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "A modular family 19 chitinase found in the prokaryotic organism Streptomyces griseus HUT 6037."
      Ohno T., Sylvie A., Hata T., Nikaidou N., Bernard H., Mitsutomi M., Watanabe T.
      J. Bacteriol. 178:5065-5070(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: HUT 6037Imported.
    2. Watanabe T., Nikaidou N., Ohno T., Mitsutomi M., Barnard H., Hata T., Sylvie A.
      Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: HUT 6037Imported.
    3. "Identification of the substrate interaction region of the chitin-binding domain of Streptomyces griseus chitinase C."
      Akagi K., Watanabe J., Hara M., Kezuka Y., Chikaishi E., Yamaguchi T., Akutsu H., Nonaka T., Watanabe T., Ikegami T.
      J. Biochem. 139:483-493(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: STRUCTURE BY NMR OF 30-82.
    4. "Structural studies of a two-domain chitinase from Streptomyces griseus HUT6037."
      Kezuka Y., Ohishi M., Itoh Y., Watanabe J., Mitsutomi M., Watanabe T., Nonaka T.
      J. Mol. Biol. 358:472-484(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 30-294, ACTIVE SITE.

    Entry informationi

    Entry nameiO50152_STRGR
    AccessioniPrimary (citable) accession number: O50152
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 1998
    Last sequence update: June 1, 1998
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3