Skip Header

Contribute Send feedback
Read comments (?) or add your own

O50129 (PGP_PYRHO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycolate phosphatase
Short name=PGP
Short name=PGPase
EC=3.1.3.18
Gene names
Ordered Locus Names:PH1421
OrganismPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]
Taxonomic identifier70601 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the dephosphorylation of 2-phosphoglycolate By similarity. HAMAP MF_01419

Catalytic activity

2-phosphoglycolate + H2O = glycolate + phosphate. HAMAP MF_01419

Cofactor

Magnesium By similarity. HAMAP MF_01419

Sequence similarities

Belongs to the archaeal SPP-like hydrolase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycolate phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 231231Phosphoglycolate phosphatase HAMAP MF_01419
PRO_0000146725

Sites

Active site91Nucleophile By similarity
Metal binding91Magnesium By similarity
Metal binding111Magnesium By similarity
Metal binding1771Magnesium By similarity
Metal binding1811Magnesium By similarity
Binding site1541Substrate By similarity

Secondary structure

1 .............................................. 231
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O50129 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: AAE2AEB8733E14A8

FASTA23125,606
        10         20         30         40         50         60 
MKIKAISIDI DGTITYPNRM IHEKALEAIR RAESLGIPIM LVTGNTVQFA EAASILIGTS 

        70         80         90        100        110        120 
GPVVAEDGGA ISYKKKRIFL ASMDEEWILW NEIRKRFPNA RTSYTMPDRR AGLVIMRETI 

       130        140        150        160        170        180 
NVETVREIIN ELNLNLVAVD SGFAIHVKKP WINKGSGIEK ASEFLGIKPK EVAHVGDGEN 

       190        200        210        220        230 
DLDAFKVVGY KVAVAQAPKI LKENADYVTK KEYGEGGAEA IYHILEKFGY L

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000001 Genomic DNA. Translation: BAA30527.1.
PIRG71015.
RefSeqNP_143292.1. NC_000961.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1WR8X-ray1.60A/B1-231[»]
ProteinModelPortalO50129.
SMRO50129. Positions 1-231.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBPYRT00000001166; EBPYRP00000001166; EBPYRG00000001166.
GeneID1443741.
GenomeReviewsGene locus PH1421 in contig BA000001_GR.
KEGGpho:PH1421.
NMPDRfig|70601.1.peg.1394.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000023028.
HOGENOMHBG551920.
OMAVTGNTVQ.
PhylomeDBO50129.
ProtClustDBPRK01158.

Enzyme and pathway databases

BioCycPHOR70601:PH1421-MONOMER.

Family and domain databases

HAMAPMF_01419. GPH_hydrolase_arch.
[Tree]
InterProIPR005834. Dehalogen-like_hydro.
IPR023214. HAD-like_dom.
IPR006382. SPPlik_hydro_arc.
IPR006378. Suc_phosP.
[Graphical view]
Gene3DG3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
KOK07024.
PfamPF00702. Hydrolase. 1 hit.
[Graphical view]
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01487. SPP-like. 1 hit.
TIGR01482. SPP-subfamily. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGP_PYRHO
AccessionPrimary (citable) accession number: O50129
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 1998
Last modified: December 14, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents