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Protein

Phosphoinositide phospholipase C

Gene

plc3

Organism
Solanum tuberosum (Potato)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported, TransducerSAAS annotation
Biological processLipid degradationUniRule annotationSAAS annotation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoinositide phospholipase CUniRule annotation (EC:3.1.4.11UniRule annotation)
Gene namesi
Name:plc3Imported
OrganismiSolanum tuberosum (Potato)Imported
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum

Subcellular locationi

Expressioni

Gene expression databases

ExpressionAtlasiO49952 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliO49952
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini109 – 252PI-PLC X-boxInterPro annotationAdd BLAST144
Domaini350 – 436PI-PLC Y-boxInterPro annotationAdd BLAST87
Domaini443 – 550C2InterPro annotationAdd BLAST108

Phylogenomic databases

eggNOGiKOG0169 Eukaryota
ENOG410XPSW LUCA
KOiK05857

Family and domain databases

Gene3Di2.60.40.150, 1 hit
3.20.20.190, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR011992 EF-hand-dom_pair
IPR001192 PI-PLC_fam
IPR017946 PLC-like_Pdiesterase_TIM-brl
IPR015359 PLC_EF-hand-like
IPR000909 PLipase_C_PInositol-sp_X_dom
IPR001711 PLipase_C_Pinositol-sp_Y
PANTHERiPTHR10336 PTHR10336, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF09279 EF-hand_like, 1 hit
PF00388 PI-PLC-X, 1 hit
PF00387 PI-PLC-Y, 1 hit
PRINTSiPR00390 PHPHLIPASEC
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00148 PLCXc, 1 hit
SM00149 PLCYc, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF51695 SSF51695, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit
PS50007 PIPLC_X_DOMAIN, 1 hit
PS50008 PIPLC_Y_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

O49952-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKQSYRVCF CFRRRFRVLA AEAPADVKNL FNRYSDNGVM SAENLHRFLI
60 70 80 90 100
EVQKEENATL EDAHAIMNNL HDLKILNIFH RRGLHLDAFF KYLFADINPP
110 120 130 140 150
LNSKLGIHQD MNAPLSHYFI YTGHNSYLTG NQLSSDCSDV PIIQALHRGV
160 170 180 190 200
RVIELDIWPN SAKDDVEVLH GGTLTTPVAL IKCLKSIKEH AFTVSEYPVV
210 220 230 240 250
ITLEDHLTTD LQAKTAEMIT QTFGDMLFSS DSCLKEFPSP ESLKRRVLIS
260 270 280 290 300
TKPPKEYLQA KEVNETGAMK GTDQTDTEAW GREVSDIKAR YNDKDDSDEG
310 320 330 340 350
EADDSDEEDP TSQQNTAPEY RRLIAIHAGK GKGGLSDWLR VDPDKVRRLS
360 370 380 390 400
LSEQELGKAV VTHGKEIIRF TQRNILRIYP KGIRFDSSNY NPFNAWTHGA
410 420 430 440 450
QMVAFNMQGY GRSLWLMHGM FRGNGGCGYV KKPDILLKAG PNNEVFDPEA
460 470 480 490 500
NLPVKTTLKV TVFMGEGWYY DFEHTHFDAY SPPDFYARIG IAGVDADIVM
510 520 530 540 550
KKTKTLEDNW IPTWDEQFEF PLTVPELALL RVEVHEYDMS EKDDFAGQTC
560 570 580
LPVSELRQGI RAVPLHNRKG EKYNSVKLLL RFEFI
Length:585
Mass (Da):66,610
Last modified:June 1, 1998 - v1
Checksum:i9AC15C36F7A3544C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X94289 mRNA Translation: CAA63954.1
PIRiT07425
RefSeqiNP_001275400.1, NM_001288471.1
UniGeneiStu.18570

Genome annotation databases

GeneIDi102588383
KEGGisot:102588383

Similar proteinsi

Entry informationi

Entry nameiO49952_SOLTU
AccessioniPrimary (citable) accession number: O49952
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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