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Protein

Phosphoinositide phospholipase C

Gene
N/A
Organism
Nicotiana rustica (Aztec tobacco)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported, TransducerSAAS annotation
Biological processLipid degradationUniRule annotationSAAS annotation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoinositide phospholipase CUniRule annotation (EC:3.1.4.11UniRule annotation)
OrganismiNicotiana rustica (Aztec tobacco)Imported
Taxonomic identifieri4093 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Subcellular locationi

Structurei

3D structure databases

ProteinModelPortaliO49902
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini108 – 252PI-PLC X-boxInterPro annotationAdd BLAST145
Domaini353 – 439PI-PLC Y-boxInterPro annotationAdd BLAST87
Domaini446 – 553C2InterPro annotationAdd BLAST108

Family and domain databases

Gene3Di2.60.40.150, 1 hit
3.20.20.190, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR011992 EF-hand-dom_pair
IPR001192 PI-PLC_fam
IPR017946 PLC-like_Pdiesterase_TIM-brl
IPR000909 PLipase_C_PInositol-sp_X_dom
IPR001711 PLipase_C_Pinositol-sp_Y
PANTHERiPTHR10336 PTHR10336, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF00388 PI-PLC-X, 1 hit
PF00387 PI-PLC-Y, 1 hit
PRINTSiPR00390 PHPHLIPASEC
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00148 PLCXc, 1 hit
SM00149 PLCYc, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF51695 SSF51695, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit
PS50007 PIPLC_X_DOMAIN, 1 hit
PS50008 PIPLC_Y_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

O49902-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSYRVCVCF TRKFRVTEAE PPSDVKEAFK KYAENGNQMN SEQLLKFLIE
60 70 80 90 100
VQGETLFTVG DSDVIVRQIL QKRHPITKLT RQTLALEDFH HFLFNTDLNP
110 120 130 140 150
PINYKVHHDM NAPLSHYFIF TGHNSYLTGN QLTSDCSDVP IIKALKKGVR
160 170 180 190 200
VIELDIWPNS DKDDIHVLHG RTVTTPVELI RCLKSIKEHA FVASPYPVVI
210 220 230 240 250
TLEDHLTPDL QAKVAQMLTE TFGEMLFVPE SDSLKECPTP EELKHRIIVS
260 270 280 290 300
TKPPKEYLEA SASTTVSKER RNSSQRSNCS EDDVWGTEPS SLTADQEENE
310 320 330 340 350
KSDSDNFEDE DDCNHRPQFA SAYKRLIAIH AGKPKGGLKE ALKVDPDKVR
360 370 380 390 400
RLSLSEQALE KAAESHGTEI VRFTQRNILR VYPKGTRFNS SNYKPLIGWM
410 420 430 440 450
HGAQMVAFNM QGYGRALWLM HGMFRSNGGC GYVKKPDFLL NVGPNNEVFD
460 470 480 490 500
PKAKLPVKKT LKVKVYMGDG WHLDFKQTHF DLYSPPDFYT RVGIAGVPAD
510 520 530 540 550
EIMKKTKTKE DKWTPVWDEA FTFPLTVPEL ALLRIEVHEY DMSEKDDFAG
560 570 580
QTCIPISELK PGIHAVPLCD RKGEKYSSVR LLMRFEFV
Length:588
Mass (Da):66,942
Last modified:June 1, 1998 - v1
Checksum:iC132712EE2E1220E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11931 mRNA Translation: CAA72681.1

Similar proteinsi

Entry informationi

Entry nameiO49902_NICRU
AccessioniPrimary (citable) accession number: O49902
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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