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Protein

Probable L-type lectin-domain containing receptor kinase VII.2

Gene

LECRK72

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei376 – 3761ATPPROSITE-ProRule annotation
Active sitei475 – 4751Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3639ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. carbohydrate binding Source: UniProtKB-KW
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G28350-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable L-type lectin-domain containing receptor kinase VII.2 (EC:2.7.11.1)
Short name:
Arabidopsis thaliana lectin-receptor kinase d
Short name:
AthlecRK-d
Short name:
LecRK-VII.2
Gene namesi
Name:LECRK72
Synonyms:LECRKD
Ordered Locus Names:At4g28350
ORF Names:F20O9.40
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G28350.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini24 – 290267ExtracellularSequence AnalysisAdd
BLAST
Transmembranei291 – 31121HelicalSequence AnalysisAdd
BLAST
Topological domaini312 – 681370CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 681658Probable L-type lectin-domain containing receptor kinase VII.2PRO_0000403100Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi31 – 311N-linked (GlcNAc...)Sequence Analysis
Glycosylationi42 – 421N-linked (GlcNAc...)Sequence Analysis
Glycosylationi56 – 561N-linked (GlcNAc...)Sequence Analysis
Glycosylationi72 – 721N-linked (GlcNAc...)Sequence Analysis
Glycosylationi126 – 1261N-linked (GlcNAc...)Sequence Analysis
Glycosylationi202 – 2021N-linked (GlcNAc...)Sequence Analysis
Glycosylationi207 – 2071N-linked (GlcNAc...)Sequence Analysis
Glycosylationi228 – 2281N-linked (GlcNAc...)Sequence Analysis
Glycosylationi263 – 2631N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriO49445.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G28350.1-P.

Structurei

3D structure databases

ProteinModelPortaliO49445.
SMRiO49445. Positions 32-290, 318-646.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini349 – 624276Protein kinasePROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 260237Legume-lectin likeAdd
BLAST

Sequence similaritiesi

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the N-terminal section; belongs to the leguminous lectin family.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
InParanoidiO49445.
PhylomeDBiO49445.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O49445-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSKVSILLF SLASLLLFRS TTGIEFIYNS NFTTTNTLLL GNATVKSPPS
60 70 80 90 100
ILTLTNQTTF SIGRGLYPSR INASSSSASP LPFATSFIFS MAPFKHLSPG
110 120 130 140 150
HGFAFVFLPF SETSAASSSQ HLGLFNFTNN GDPNSRIFAV EFDVFANQEF
160 170 180 190 200
NDINDNHVGV DVNSLTSVAS ETAGFYGGRD GQRFTELKLN SGENYQAWIE
210 220 230 240 250
FNGSAINVTM ARASSRKPIR PLISIPLNLT GVLLDDMFVG FTASTGQLVQ
260 270 280 290 300
SHRILSWSFS NSNFSIGDAL ITRNLPSFKL SGDSVLKSKG FIAGVSSGVV
310 320 330 340 350
LLVSVIGLLC FYVVRRRRQR LEGDVEDWET EYWPHRVQYK DVLEATKGFS
360 370 380 390 400
DENMIGYGGN SKVYRGVLEG KEVAVKRIMM SPRESVGATS EFLAEVSSLG
410 420 430 440 450
RLRHKNIVGL KGWSKKGGES LILIYEYMEN GSVDKRIFDC NEMLNWEERM
460 470 480 490 500
RVIRDLASGM LYLHEGWETK VLHRDIKSSN VLLDKDMNAR VGDFGLAKLQ
510 520 530 540 550
NTSKEMVSTT HVVGTAGYMA PELVKTGRAS AQTDVYSFGV FVLEVVCGRR
560 570 580 590 600
PIEEGREGIV EWIWGLMEKD KVVDGLDERI KANGVFVVEE VEMALRIGLL
610 620 630 640 650
CVHPDPRVRP KMRQVVQILE QGRLVEDGGE REISLLERVK SSYLLETGEG
660 670 680
SRQQHPTFQD VWNSSSYSNS FQTYDSILHG R
Length:681
Mass (Da):75,711
Last modified:January 10, 2011 - v2
Checksum:i90976C44555BA271
GO

Sequence cautioni

The sequence AEE85472.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence CAA16875.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence CAB79637.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021749 Genomic DNA. Translation: CAA16875.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79637.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85472.1. Sequence problems.
PIRiT04606.
RefSeqiNP_194564.1. NM_118975.1.
UniGeneiAt.32024.

Genome annotation databases

EnsemblPlantsiAT4G28350.1; AT4G28350.1; AT4G28350.
GeneIDi828950.
KEGGiath:AT4G28350.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021749 Genomic DNA. Translation: CAA16875.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79637.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85472.1. Sequence problems.
PIRiT04606.
RefSeqiNP_194564.1. NM_118975.1.
UniGeneiAt.32024.

3D structure databases

ProteinModelPortaliO49445.
SMRiO49445. Positions 32-290, 318-646.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G28350.1-P.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G28350.1; AT4G28350.1; AT4G28350.
GeneIDi828950.
KEGGiath:AT4G28350.

Organism-specific databases

GeneFarmi95. 4.
TAIRiAT4G28350.

Phylogenomic databases

eggNOGiCOG0515.
InParanoidiO49445.
PhylomeDBiO49445.

Enzyme and pathway databases

BioCyciARA:AT4G28350-MONOMER.

Gene expression databases

GenevestigatoriO49445.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
    Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
    Plant Mol. Biol. 39:671-682(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.
  4. Cited for: GENE FAMILY.
  5. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
    Bouwmeester K., Govers F.
    J. Exp. Bot. 60:4383-4396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiLRK72_ARATH
AccessioniPrimary (citable) accession number: O49445
Secondary accession number(s): F4JL83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2011
Last sequence update: January 10, 2011
Last modified: January 6, 2015
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.