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O49445

- LRK72_ARATH

UniProt

O49445 - LRK72_ARATH

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Protein

Probable L-type lectin-domain containing receptor kinase VII.2

Gene
LECRK72, LECRKD, At4g28350, F20O9.40
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei376 – 3761ATP By similarity
Active sitei475 – 4751Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3639ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. carbohydrate binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G28350-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable L-type lectin-domain containing receptor kinase VII.2 (EC:2.7.11.1)
Short name:
Arabidopsis thaliana lectin-receptor kinase d
Short name:
AthlecRK-d
Short name:
LecRK-VII.2
Gene namesi
Name:LECRK72
Synonyms:LECRKD
Ordered Locus Names:At4g28350
ORF Names:F20O9.40
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 4

Organism-specific databases

TAIRiAT4G28350.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini24 – 290267Extracellular Reviewed predictionAdd
BLAST
Transmembranei291 – 31121Helical; Reviewed predictionAdd
BLAST
Topological domaini312 – 681370Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323 Reviewed predictionAdd
BLAST
Chaini24 – 681658Probable L-type lectin-domain containing receptor kinase VII.2PRO_0000403100Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi31 – 311N-linked (GlcNAc...) Reviewed prediction
Glycosylationi42 – 421N-linked (GlcNAc...) Reviewed prediction
Glycosylationi56 – 561N-linked (GlcNAc...) Reviewed prediction
Glycosylationi72 – 721N-linked (GlcNAc...) Reviewed prediction
Glycosylationi126 – 1261N-linked (GlcNAc...) Reviewed prediction
Glycosylationi202 – 2021N-linked (GlcNAc...) Reviewed prediction
Glycosylationi207 – 2071N-linked (GlcNAc...) Reviewed prediction
Glycosylationi228 – 2281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi263 – 2631N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriO49445.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G28350.1-P.

Structurei

3D structure databases

ProteinModelPortaliO49445.
SMRiO49445. Positions 30-290, 318-667.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini349 – 624276Protein kinaseAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 260237Legume-lectin likeAdd
BLAST

Sequence similaritiesi

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
In the N-terminal section; belongs to the leguminous lectin family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
InParanoidiO49445.
PhylomeDBiO49445.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O49445-1 [UniParc]FASTAAdd to Basket

« Hide

MFSKVSILLF SLASLLLFRS TTGIEFIYNS NFTTTNTLLL GNATVKSPPS    50
ILTLTNQTTF SIGRGLYPSR INASSSSASP LPFATSFIFS MAPFKHLSPG 100
HGFAFVFLPF SETSAASSSQ HLGLFNFTNN GDPNSRIFAV EFDVFANQEF 150
NDINDNHVGV DVNSLTSVAS ETAGFYGGRD GQRFTELKLN SGENYQAWIE 200
FNGSAINVTM ARASSRKPIR PLISIPLNLT GVLLDDMFVG FTASTGQLVQ 250
SHRILSWSFS NSNFSIGDAL ITRNLPSFKL SGDSVLKSKG FIAGVSSGVV 300
LLVSVIGLLC FYVVRRRRQR LEGDVEDWET EYWPHRVQYK DVLEATKGFS 350
DENMIGYGGN SKVYRGVLEG KEVAVKRIMM SPRESVGATS EFLAEVSSLG 400
RLRHKNIVGL KGWSKKGGES LILIYEYMEN GSVDKRIFDC NEMLNWEERM 450
RVIRDLASGM LYLHEGWETK VLHRDIKSSN VLLDKDMNAR VGDFGLAKLQ 500
NTSKEMVSTT HVVGTAGYMA PELVKTGRAS AQTDVYSFGV FVLEVVCGRR 550
PIEEGREGIV EWIWGLMEKD KVVDGLDERI KANGVFVVEE VEMALRIGLL 600
CVHPDPRVRP KMRQVVQILE QGRLVEDGGE REISLLERVK SSYLLETGEG 650
SRQQHPTFQD VWNSSSYSNS FQTYDSILHG R 681
Length:681
Mass (Da):75,711
Last modified:January 11, 2011 - v2
Checksum:i90976C44555BA271
GO

Sequence cautioni

The sequence AEE85472.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAA16875.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAB79637.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL021749 Genomic DNA. Translation: CAA16875.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79637.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85472.1. Sequence problems.
PIRiT04606.
RefSeqiNP_194564.1. NM_118975.1.
UniGeneiAt.32024.

Genome annotation databases

EnsemblPlantsiAT4G28350.1; AT4G28350.1; AT4G28350.
GeneIDi828950.
KEGGiath:AT4G28350.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL021749 Genomic DNA. Translation: CAA16875.1 . Sequence problems.
AL161572 Genomic DNA. Translation: CAB79637.1 . Sequence problems.
CP002687 Genomic DNA. Translation: AEE85472.1 . Sequence problems.
PIRi T04606.
RefSeqi NP_194564.1. NM_118975.1.
UniGenei At.32024.

3D structure databases

ProteinModelPortali O49445.
SMRi O49445. Positions 30-290, 318-667.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT4G28350.1-P.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT4G28350.1 ; AT4G28350.1 ; AT4G28350 .
GeneIDi 828950.
KEGGi ath:AT4G28350.

Organism-specific databases

GeneFarmi 95. 4.
TAIRi AT4G28350.

Phylogenomic databases

eggNOGi COG0515.
InParanoidi O49445.
PhylomeDBi O49445.

Enzyme and pathway databases

BioCyci ARA:AT4G28350-MONOMER.

Gene expression databases

Genevestigatori O49445.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
    Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
    Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.
  4. Cited for: GENE FAMILY.
  5. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
    Bouwmeester K., Govers F.
    J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiLRK72_ARATH
AccessioniPrimary (citable) accession number: O49445
Secondary accession number(s): F4JL83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: January 11, 2011
Last modified: June 11, 2014
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi