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O49445 (LRK72_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable L-type lectin-domain containing receptor kinase VII.2

Short name=Arabidopsis thaliana lectin-receptor kinase d
Short name=AthlecRK-d
Short name=LecRK-VII.2
EC=2.7.11.1
Gene names
Name:LECRK72
Synonyms:LECRKD
Ordered Locus Names:At4g28350
ORF Names:F20O9.40
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length681 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

In the N-terminal section; belongs to the leguminous lectin family.

Contains 1 protein kinase domain.

Sequence caution

The sequence AEE85472.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAA16875.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAB79637.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 681658Probable L-type lectin-domain containing receptor kinase VII.2
PRO_0000403100

Regions

Topological domain24 – 290267Extracellular Potential
Transmembrane291 – 31121Helical; Potential
Topological domain312 – 681370Cytoplasmic Potential
Domain349 – 624276Protein kinase
Nucleotide binding355 – 3639ATP By similarity
Region24 – 260237Legume-lectin like

Sites

Active site4751Proton acceptor By similarity
Binding site3761ATP By similarity

Amino acid modifications

Glycosylation311N-linked (GlcNAc...) Potential
Glycosylation421N-linked (GlcNAc...) Potential
Glycosylation561N-linked (GlcNAc...) Potential
Glycosylation721N-linked (GlcNAc...) Potential
Glycosylation1261N-linked (GlcNAc...) Potential
Glycosylation2021N-linked (GlcNAc...) Potential
Glycosylation2071N-linked (GlcNAc...) Potential
Glycosylation2281N-linked (GlcNAc...) Potential
Glycosylation2631N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O49445 [UniParc].

Last modified January 11, 2011. Version 2.
Checksum: 90976C44555BA271

FASTA68175,711
        10         20         30         40         50         60 
MFSKVSILLF SLASLLLFRS TTGIEFIYNS NFTTTNTLLL GNATVKSPPS ILTLTNQTTF 

        70         80         90        100        110        120 
SIGRGLYPSR INASSSSASP LPFATSFIFS MAPFKHLSPG HGFAFVFLPF SETSAASSSQ 

       130        140        150        160        170        180 
HLGLFNFTNN GDPNSRIFAV EFDVFANQEF NDINDNHVGV DVNSLTSVAS ETAGFYGGRD 

       190        200        210        220        230        240 
GQRFTELKLN SGENYQAWIE FNGSAINVTM ARASSRKPIR PLISIPLNLT GVLLDDMFVG 

       250        260        270        280        290        300 
FTASTGQLVQ SHRILSWSFS NSNFSIGDAL ITRNLPSFKL SGDSVLKSKG FIAGVSSGVV 

       310        320        330        340        350        360 
LLVSVIGLLC FYVVRRRRQR LEGDVEDWET EYWPHRVQYK DVLEATKGFS DENMIGYGGN 

       370        380        390        400        410        420 
SKVYRGVLEG KEVAVKRIMM SPRESVGATS EFLAEVSSLG RLRHKNIVGL KGWSKKGGES 

       430        440        450        460        470        480 
LILIYEYMEN GSVDKRIFDC NEMLNWEERM RVIRDLASGM LYLHEGWETK VLHRDIKSSN 

       490        500        510        520        530        540 
VLLDKDMNAR VGDFGLAKLQ NTSKEMVSTT HVVGTAGYMA PELVKTGRAS AQTDVYSFGV 

       550        560        570        580        590        600 
FVLEVVCGRR PIEEGREGIV EWIWGLMEKD KVVDGLDERI KANGVFVVEE VEMALRIGLL 

       610        620        630        640        650        660 
CVHPDPRVRP KMRQVVQILE QGRLVEDGGE REISLLERVK SSYLLETGEG SRQQHPTFQD 

       670        680 
VWNSSSYSNS FQTYDSILHG R 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
[4]"Lectin receptor kinases in plants."
Barre A., Herve C., Lescure B., Rouge P.
Crit. Rev. Plant Sci. 21:379-399(2002)
Cited for: GENE FAMILY.
[5]"Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
Bouwmeester K., Govers F.
J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL021749 Genomic DNA. Translation: CAA16875.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79637.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85472.1. Sequence problems.
PIRT04606.
RefSeqNP_194564.1. NM_118975.1.
UniGeneAt.32024.

3D structure databases

ProteinModelPortalO49445.
SMRO49445. Positions 30-290, 336-667.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT4G28350.1-P.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID828950.
KEGGath:AT4G28350.

Organism-specific databases

GeneFarm95. 4.
TAIRAT4G28350.

Phylogenomic databases

eggNOGCOG0515.
InParanoidO49445.
PhylomeDBO49445.
ProtClustDBCLSN2685730.

Enzyme and pathway databases

BioCycARA:AT4G28350-MONOMER.

Gene expression databases

GenevestigatorO49445.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLRK72_ARATH
AccessionPrimary (citable) accession number: O49445
Secondary accession number(s): F4JL83
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: January 11, 2011
Last modified: April 16, 2014
This is version 110 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names