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O49445

- LRK72_ARATH

UniProt

O49445 - LRK72_ARATH

Protein

Probable L-type lectin-domain containing receptor kinase VII.2

Gene

LECRK72

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 113 (01 Oct 2014)
      Sequence version 2 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei376 – 3761ATPPROSITE-ProRule annotation
    Active sitei475 – 4751Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi355 – 3639ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. carbohydrate binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Receptor, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Lectin, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT4G28350-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable L-type lectin-domain containing receptor kinase VII.2 (EC:2.7.11.1)
    Short name:
    Arabidopsis thaliana lectin-receptor kinase d
    Short name:
    AthlecRK-d
    Short name:
    LecRK-VII.2
    Gene namesi
    Name:LECRK72
    Synonyms:LECRKD
    Ordered Locus Names:At4g28350
    ORF Names:F20O9.40
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 4

    Organism-specific databases

    TAIRiAT4G28350.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 681658Probable L-type lectin-domain containing receptor kinase VII.2PRO_0000403100Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi31 – 311N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi42 – 421N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi56 – 561N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi72 – 721N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi126 – 1261N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi202 – 2021N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi207 – 2071N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi228 – 2281N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi263 – 2631N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Expressioni

    Gene expression databases

    GenevestigatoriO49445.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT4G28350.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliO49445.
    SMRiO49445. Positions 30-290, 318-667.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini24 – 290267ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini312 – 681370CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei291 – 31121HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini349 – 624276Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 260237Legume-lectin likeAdd
    BLAST

    Sequence similaritiesi

    In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
    In the N-terminal section; belongs to the leguminous lectin family.Curated
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0515.
    InParanoidiO49445.
    PhylomeDBiO49445.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O49445-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFSKVSILLF SLASLLLFRS TTGIEFIYNS NFTTTNTLLL GNATVKSPPS    50
    ILTLTNQTTF SIGRGLYPSR INASSSSASP LPFATSFIFS MAPFKHLSPG 100
    HGFAFVFLPF SETSAASSSQ HLGLFNFTNN GDPNSRIFAV EFDVFANQEF 150
    NDINDNHVGV DVNSLTSVAS ETAGFYGGRD GQRFTELKLN SGENYQAWIE 200
    FNGSAINVTM ARASSRKPIR PLISIPLNLT GVLLDDMFVG FTASTGQLVQ 250
    SHRILSWSFS NSNFSIGDAL ITRNLPSFKL SGDSVLKSKG FIAGVSSGVV 300
    LLVSVIGLLC FYVVRRRRQR LEGDVEDWET EYWPHRVQYK DVLEATKGFS 350
    DENMIGYGGN SKVYRGVLEG KEVAVKRIMM SPRESVGATS EFLAEVSSLG 400
    RLRHKNIVGL KGWSKKGGES LILIYEYMEN GSVDKRIFDC NEMLNWEERM 450
    RVIRDLASGM LYLHEGWETK VLHRDIKSSN VLLDKDMNAR VGDFGLAKLQ 500
    NTSKEMVSTT HVVGTAGYMA PELVKTGRAS AQTDVYSFGV FVLEVVCGRR 550
    PIEEGREGIV EWIWGLMEKD KVVDGLDERI KANGVFVVEE VEMALRIGLL 600
    CVHPDPRVRP KMRQVVQILE QGRLVEDGGE REISLLERVK SSYLLETGEG 650
    SRQQHPTFQD VWNSSSYSNS FQTYDSILHG R 681
    Length:681
    Mass (Da):75,711
    Last modified:January 11, 2011 - v2
    Checksum:i90976C44555BA271
    GO

    Sequence cautioni

    The sequence AEE85472.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence CAA16875.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence CAB79637.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL021749 Genomic DNA. Translation: CAA16875.1. Sequence problems.
    AL161572 Genomic DNA. Translation: CAB79637.1. Sequence problems.
    CP002687 Genomic DNA. Translation: AEE85472.1. Sequence problems.
    PIRiT04606.
    RefSeqiNP_194564.1. NM_118975.1.
    UniGeneiAt.32024.

    Genome annotation databases

    EnsemblPlantsiAT4G28350.1; AT4G28350.1; AT4G28350.
    GeneIDi828950.
    KEGGiath:AT4G28350.

    Cross-referencesi

    Web resourcesi

    PlantP kinase Classification PPC

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL021749 Genomic DNA. Translation: CAA16875.1 . Sequence problems.
    AL161572 Genomic DNA. Translation: CAB79637.1 . Sequence problems.
    CP002687 Genomic DNA. Translation: AEE85472.1 . Sequence problems.
    PIRi T04606.
    RefSeqi NP_194564.1. NM_118975.1.
    UniGenei At.32024.

    3D structure databases

    ProteinModelPortali O49445.
    SMRi O49445. Positions 30-290, 318-667.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT4G28350.1-P.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT4G28350.1 ; AT4G28350.1 ; AT4G28350 .
    GeneIDi 828950.
    KEGGi ath:AT4G28350.

    Organism-specific databases

    GeneFarmi 95. 4.
    TAIRi AT4G28350.

    Phylogenomic databases

    eggNOGi COG0515.
    InParanoidi O49445.
    PhylomeDBi O49445.

    Enzyme and pathway databases

    BioCyci ARA:AT4G28350-MONOMER.

    Gene expression databases

    Genevestigatori O49445.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
      Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
      , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
      Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
      Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
      Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY.
    4. Cited for: GENE FAMILY.
    5. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
      Bouwmeester K., Govers F.
      J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiLRK72_ARATH
    AccessioniPrimary (citable) accession number: O49445
    Secondary accession number(s): F4JL83
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 113 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3