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Protein

Indoleacetaldoxime dehydratase

Gene

CYP71A13

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the biosynthesis of the indole-derived phytoalexin camalexin. Catalyzes the conversion of indole-3-acetaldoxime to indole-3-acetonitrile. Required for resistance to A.brassicicola and B.cinerea.2 Publications

Catalytic activityi

(Indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processPlant defense

Enzyme and pathway databases

BioCyciARA:AT2G30770-MONOMER
MetaCyc:AT2G30770-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Indoleacetaldoxime dehydratase (EC:4.99.1.6)
Alternative name(s):
Cytochrome P450 71A13
Gene namesi
Name:CYP71A13
Ordered Locus Names:At2g30770
ORF Names:T11J7.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G30770

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei2 – 20HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000520641 – 497Indoleacetaldoxime dehydrataseAdd BLAST497

Proteomic databases

PaxDbiO49342

Expressioni

Inductioni

By Pseudomonas syringae pv. tomato DC3000, Botrytis cinerea, flagellin, BTH and UV-C. Repressed by the transcription factors WRKY18 and WRKY40 upon infection with Golovinomyces orontii.4 Publications

Gene expression databases

ExpressionAtlasiO49342 baseline and differential
GenevisibleiO49342 AT

Interactioni

Protein-protein interaction databases

BioGridi2977, 1 interactor
IntActiO49342, 1 interactor
STRINGi3702.AT2G30770.1

Structurei

3D structure databases

ProteinModelPortaliO49342
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi164 – 169Poly-Ser6

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
HOGENOMiHOG000218629
InParanoidiO49342
KOiK11868
OrthoDBiEOG09360BN4
PhylomeDBiO49342

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

O49342-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMILSISLC LTTLITLLLL RRFLKRTATK VNLPPSPWRL PVIGNLHQLS
60 70 80 90 100
LHPHRSLRSL SLRYGPLMLL HFGRVPILVV SSGEAAQEVL KTHDHKFANR
110 120 130 140 150
PRSKAVHGLM NGGRDVVFAP YGEYWRQMKS VCILNLLTNK MVESFEKVRE
160 170 180 190 200
DEVNAMIEKL EKASSSSSSE NLSELFITLP SDVTSRVALG RKHSEDETAR
210 220 230 240 250
DLKKRVRQIM ELLGEFPIGE YVPILAWIDG IRGFNNKIKE VSRGFSDLMD
260 270 280 290 300
KVVQEHLEAS NDKADFVDIL LSIEKDKNSG FQVQRNDIKF MILDMFIGGT
310 320 330 340 350
STTSTLLEWT MTELIRSPKS MKKLQDEIRS TIRPHGSYIK EKEVENMKYL
360 370 380 390 400
KAVIKEVLRL HPSLPMILPR LLSEDVKVKG YNIAAGTEVI INAWAIQRDT
410 420 430 440 450
AIWGPDAEEF KPERHLDSGL DYHGKNLNYI PFGSGRRICP GINLALGLAE
460 470 480 490
VTVANLVGRF DWRVEAGPNG DQPDLTEAIG IDVCRKFPLI AFPSSVV
Length:497
Mass (Da):56,086
Last modified:June 1, 1998 - v1
Checksum:i3C8CE0773624B59B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002340 Genomic DNA Translation: AAC02748.1
CP002685 Genomic DNA Translation: AEC08439.2
BX820453 mRNA No translation available.
PIRiE84712
RefSeqiNP_180635.3, NM_128630.3
UniGeneiAt.20309
At.68697

Genome annotation databases

EnsemblPlantsiAT2G30770.1; AT2G30770.1; AT2G30770
GeneIDi817628
GrameneiAT2G30770.1; AT2G30770.1; AT2G30770
KEGGiath:AT2G30770

Similar proteinsi

Entry informationi

Entry nameiC71AD_ARATH
AccessioniPrimary (citable) accession number: O49342
Secondary accession number(s): F4INY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: June 1, 1998
Last modified: April 25, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health