Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Indoleacetaldoxime dehydratase

Gene

CYP71A13

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the biosynthesis of the indole-derived phytoalexin camalexin. Catalyzes the conversion of indole-3-acetaldoxime to indole-3-acetonitrile. Required for resistance to A.brassicicola and B.cinerea.2 Publications

Catalytic activityi

(Indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O.1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Plant defense

Enzyme and pathway databases

BioCyciARA:AT2G30770-MONOMER.
MetaCyc:AT2G30770-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Indoleacetaldoxime dehydratase (EC:4.99.1.6)
Alternative name(s):
Cytochrome P450 71A13
Gene namesi
Name:CYP71A13
Ordered Locus Names:At2g30770
ORF Names:T11J7.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G30770.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei2 – 20HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000520641 – 497Indoleacetaldoxime dehydrataseAdd BLAST497

Proteomic databases

PaxDbiO49342.

Expressioni

Inductioni

By Pseudomonas syringae pv. tomato DC3000, Botrytis cinerea, flagellin, BTH and UV-C. Repressed by the transcription factors WRKY18 and WRKY40 upon infection with Golovinomyces orontii.4 Publications

Gene expression databases

GenevisibleiO49342. AT.

Interactioni

Protein-protein interaction databases

BioGridi2977. 1 interactor.
IntActiO49342. 1 interactor.
STRINGi3702.AT2G30770.1.

Structurei

3D structure databases

ProteinModelPortaliO49342.
SMRiO49342.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi164 – 169Poly-Ser6

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000218629.
InParanoidiO49342.
KOiK11868.
OrthoDBiEOG09360BN4.
PhylomeDBiO49342.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O49342-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMILSISLC LTTLITLLLL RRFLKRTATK VNLPPSPWRL PVIGNLHQLS
60 70 80 90 100
LHPHRSLRSL SLRYGPLMLL HFGRVPILVV SSGEAAQEVL KTHDHKFANR
110 120 130 140 150
PRSKAVHGLM NGGRDVVFAP YGEYWRQMKS VCILNLLTNK MVESFEKVRE
160 170 180 190 200
DEVNAMIEKL EKASSSSSSE NLSELFITLP SDVTSRVALG RKHSEDETAR
210 220 230 240 250
DLKKRVRQIM ELLGEFPIGE YVPILAWIDG IRGFNNKIKE VSRGFSDLMD
260 270 280 290 300
KVVQEHLEAS NDKADFVDIL LSIEKDKNSG FQVQRNDIKF MILDMFIGGT
310 320 330 340 350
STTSTLLEWT MTELIRSPKS MKKLQDEIRS TIRPHGSYIK EKEVENMKYL
360 370 380 390 400
KAVIKEVLRL HPSLPMILPR LLSEDVKVKG YNIAAGTEVI INAWAIQRDT
410 420 430 440 450
AIWGPDAEEF KPERHLDSGL DYHGKNLNYI PFGSGRRICP GINLALGLAE
460 470 480 490
VTVANLVGRF DWRVEAGPNG DQPDLTEAIG IDVCRKFPLI AFPSSVV
Length:497
Mass (Da):56,086
Last modified:June 1, 1998 - v1
Checksum:i3C8CE0773624B59B
GO

Sequence cautioni

The sequence AEC08439 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002340 Genomic DNA. Translation: AAC02748.1.
CP002685 Genomic DNA. Translation: AEC08439.1. Different initiation.
BX820453 mRNA. No translation available.
PIRiE84712.
RefSeqiNP_180635.3. NM_128630.3.
UniGeneiAt.20309.
At.68697.

Genome annotation databases

EnsemblPlantsiAT2G30770.1; AT2G30770.1; AT2G30770.
GeneIDi817628.
GrameneiAT2G30770.1; AT2G30770.1; AT2G30770.
KEGGiath:AT2G30770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002340 Genomic DNA. Translation: AAC02748.1.
CP002685 Genomic DNA. Translation: AEC08439.1. Different initiation.
BX820453 mRNA. No translation available.
PIRiE84712.
RefSeqiNP_180635.3. NM_128630.3.
UniGeneiAt.20309.
At.68697.

3D structure databases

ProteinModelPortaliO49342.
SMRiO49342.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2977. 1 interactor.
IntActiO49342. 1 interactor.
STRINGi3702.AT2G30770.1.

Proteomic databases

PaxDbiO49342.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G30770.1; AT2G30770.1; AT2G30770.
GeneIDi817628.
GrameneiAT2G30770.1; AT2G30770.1; AT2G30770.
KEGGiath:AT2G30770.

Organism-specific databases

TAIRiAT2G30770.

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000218629.
InParanoidiO49342.
KOiK11868.
OrthoDBiEOG09360BN4.
PhylomeDBiO49342.

Enzyme and pathway databases

BioCyciARA:AT2G30770-MONOMER.
MetaCyc:AT2G30770-MONOMER.

Miscellaneous databases

PROiO49342.

Gene expression databases

GenevisibleiO49342. AT.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC71AD_ARATH
AccessioniPrimary (citable) accession number: O49342
Secondary accession number(s): F4INY1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: June 1, 1998
Last modified: November 30, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.