O49046 (ARGI_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginase
EC=3.5.3.1

Gene names

Name:

AG1

Organism

Glycine max (Soybean) (Glycine hispida)

Taxonomic identifier

3847 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Phaseoleae › Glycine

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	L-arginine + H2O = L-ornithine + urea.
Cofactor	Binds 2 manganese ions per subunit By similarity.
Pathway	Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
Sequence similarities	Belongs to the arginase family.

Ontologies

Keywords
Biological process	Arginine metabolism
Ligand	Manganese Metal-binding
Molecular function	Hydrolase
Gene Ontology (GO)
Molecular function	arginase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 350	350	Arginase		PRO_0000173705
Regions
	Region	195 – 199	5	Substrate binding Potential
	Region	203 – 205	3	Substrate binding Potential
Sites
	Metal binding	193	1	Manganese 1 By similarity
	Metal binding	193	1	Manganese 2 By similarity
	Metal binding	195	1	Manganese 2 By similarity
	Metal binding	197	1	Manganese 1 By similarity
	Metal binding	278	1	Manganese 1 By similarity
	Metal binding	278	1	Manganese 2 By similarity
	Metal binding	280	1	Manganese 2 By similarity
	Binding site	234	1	Substrate Potential
	Binding site	321	1	Substrate Potential

Sequences

	Sequence		Length	Mass (Da)
	O49046 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 856CF5BADC5A15D4	FASTA	350	38,610
	10 20 30 40 50 60 MSFLRSFARN KDISKVGRRG IHCMQKLCAE KISPDSLEKA QNRVIDAALT LVRENTGLRK 70 80 90 100 110 120 NLCHSLGGAV ATSTLLGVPL GHNSSFLEGP AFAPPFIREG IWCGSANSTT EEGKDLKDLR 130 140 150 160 170 180 IMVDVGDIPI QEMRDCGIGD ERLMKVVSDS VKLVMEEDPL RPLILGGDPS ISYPVVRAIS 190 200 210 220 230 240 EKLGGPVDVL HFDAHPDLYD EFEGNYYSHA SSFARIMEGG YARRLLQVGI RSINKEGREQ 250 260 270 280 290 300 AKKFGVEQFE MRHFSKDRPF LENLNLGEGA KGVYISIDVD CLDPGYAVGV SHYESGGLSF 310 320 330 340 350 RDVMNMLQNL KGDIVGGDVV EYNPQREPPD RMTAMVAAKF VRELAAKMSK

References

[1]	"Nucleotide sequence of a cDNA encoding a soybean seedling axes arginase." Goldraij A., Coello P., Polacco J.C. Plant Gene Register PGR98-016 Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Williams 82.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF035671 mRNA. Translation: AAC04613.1.
PIR	T06222.
RefSeq	NP_001237121.1. NM_001250192.1.
UniGene	Gma.2086.
3D structure databases
ProteinModelPortal	O49046.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	547994.
Gene expression databases
Genevestigator	O49046.
Family and domain databases
InterPro	IPR006035. Ureohydrolase. IPR023696. Ureohydrolase_domain. [Graphical view]
Gene3D	G3DSA:3.40.800.10. Ureohydrolase. 1 hit.
PANTHER	PTHR11358. Ureohydrolase. 1 hit.
Pfam	PF00491. Arginase. 1 hit. [Graphical view]
PIRSF	PIRSF036979. Arginase. 1 hit.
PROSITE	PS01053. ARGINASE_1. False negative. PS51409. ARGINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARGI_SOYBN

Accession

Primary (citable) accession number: O49046

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	June 1, 1998
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program