O48866 (O48866_DAUCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Cytosine-specific methyltransferase RuleBase RU000417 EC=2.1.1.37 RuleBase RU000417
Organism	Daucus carota (Carrot) EMBL AAC39355.1
Taxonomic identifier	4039 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiineae › Apiaceae › Apioideae › Scandiceae › Daucinae › Daucus

Protein attributes

Sequence length	1545 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. RuleBase RU000417
Sequence similarities	Belongs to the C5-methyltransferase family. RuleBase RU000416

Ontologies

Keywords
Molecular function	Methyltransferase RuleBase RU000417 EMBL AAC39355.1 Transferase
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA (cytosine-5-)-methyltransferase activity Inferred from electronic annotation. Source: EC DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O48866 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: C6D2BEB4D0F75CA4	FASTA	1,545	172,969
	10 20 30 40 50 60 MGSSAVVDAP ALDAGLETKK NKRKNADCDS EKTAVSGQKK QRAHALKSSE TPVGSRKMPK 70 80 90 100 110 120 RAAACADFKE KSIQISKKSS IIETKKDRSV DEEEVAVRLT AGQEDGRPCR RLTDFIFHNS 130 140 150 160 170 180 DGIPQAFEML EVDDLYISGL ILPLEDSSQK EACSIKCEGF GRIENWALSG YEEGVPTIWV 190 200 210 220 230 240 STDVADYDCV KPSASYKKHY EHLFAKATAC VEVYKKLSKS SGGNPDLSLD ELLAGVVRGL 250 260 270 280 290 300 SGMKCFSRSV SIKDFIISQG DFIYNQLVGL DETSKKTDQQ FLELPVLIAL REESSKHGDP 310 320 330 340 350 360 SIGKVASTNG TLTIGPKIKD GENKKDSATE EDEGVKVARL LQEEEFWNSM KQKKGRGSST 370 380 390 400 410 420 SSNKYYIKIN EDEIANDYPL PAYYKTANQE TDEYIIFDGG ADACYTDDLP RSMLHNWALY 430 440 450 460 470 480 NSDSRLISLE LLPMKGCADI DVTIFGSGVM TEDDGTGFNL DGDTSQSSSA GLGTANVDGI 490 500 510 520 530 540 PIYLSAIKEW MIEFGSSMVF ISIRTDMAWY RLGKPSKQYA SWYEPVLKTA RVAISIITLL 550 560 570 580 590 600 KEQARVSRLS FMDVIKRVSE FEKGHPAYIS SVPAAVERYV VVHGQIILQQ FLEFPDEKIK 610 620 630 640 650 660 KSAFVIGLTN KMEERHHTKW LMKKKKLLQR DEPNLNPRAA LAPVVSKRKA MQATTTRLIN 670 680 690 700 710 720 RIWGEFYSNY SPEDMKEGIT GEDKEEEEPE EQEEIEEEEE KETLTALEKT PTPTSTPRKT 730 740 750 760 770 780 KSIPKVKDIR WNRKSVGETL SGEALYKQAI VYGTEIAVGG AVLVDDESAQ LPAIYYVEYM 790 800 810 820 830 840 FETLNGIKML HGRMLQQGSL TILGNTANEC EVFLTNDCMD FELADVKKAV VEIRSRPWGH 850 860 870 880 890 900 QYRKVNANAD KIYRAGVEER KKNGLETEYY CKSLYCPDKG AFLSLPLNSM GLGSGICSSC 910 920 930 940 950 960 KLDKDLTEKE KFVVHSDKTS FVFNGTEYSI HDFLYVSPQQ FSTERVGNET FKGGRNVGLK 970 980 990 1000 1010 1020 AYAICQLLEI IVPKAPKQAE PHSTEIKVRR FYRPEDISDE KAYCSDIREV YYSEETHTID 1030 1040 1050 1060 1070 1080 AETVEGRCEV RKKNDLPSCD APTIFDHVFF CEYLYDPAKG SLKQLPPNIK LRYSAVKGAH 1090 1100 1110 1120 1130 1140 VSSLRKNKGK CKEGEDDLDS LKSKVNCLAT LDIFAGCGGL SEGLQKSGVC TTKWAIEYEE 1150 1160 1170 1180 1190 1200 AAGDAFKLNH PESLMFINNC NVILKAIMDK TGDADDCIST PEAAELAAKL SEEEIKNLPL 1210 1220 1230 1240 1250 1260 PGQVDFINGG PPCQGFSGMN RFNQSSWSKV QCEMILAFLS FADYYRPKYF LLENVRTFVS 1270 1280 1290 1300 1310 1320 FNKGQTFRLA IASLLDMGYQ VRFGILEAGA YGVPQSRKRA FIWAASPEET LPEWPEPMHV 1330 1340 1350 1360 1370 1380 FAAPELKIAL PENKYYAAVR STQTGAPFRS ITVRDTIGDL PMVSNGASRT SIEYQMDPIS 1390 1400 1410 1420 1430 1440 WFQKKIRANM MVLTDHISKE MNELNLIRCQ RIPKRRGADW QDLPDEKVKL SSGQLVDLIP 1450 1460 1470 1480 1490 1500 WCLPNTAKRH NQWKGLFGRL DWEGSFPTSI TDPQPMGKVG MCFHPDQHRI VTVRECARSQ 1510 1520 1530 1540 GFPDSYQFYG NILHKHQQIG NAVPPPLAYA LGMKLKEALE SKGCM

References

[1]	"Carrot DNA-methyltransferase is encoded by two classes of genes with differing patterns of expression." Bernacchia G., Primo A., Giorgetti L., Pitto L., Cella R. Plant J. 13:317-329(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF007807 mRNA. Translation: AAC39355.1.
PIR	T14288.
3D structure databases
HSSP	HSSP built from PDB template 1G55 based on UniProtKB O14717.
ProteinModelPortal	O48866.
ModBase	Search...
Protein family/group databases
REBASE	3202. M.DcaI.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001025. BAH_dom. IPR018117. C5_DNA_meth_AS. IPR001525. C5_MeTfrase. IPR022702. Cytosine_MeTrfase1_RFD. IPR017198. DNA_C5-MeTrfase_1_euk. [Graphical view]
PANTHER	PTHR10629. PTHR10629. 1 hit.
Pfam	PF01426. BAH. 2 hits. PF00145. DNA_methylase. 1 hit. PF12047. DNMT1-RFD. 2 hits. [Graphical view]
PIRSF	PIRSF037404. DNMT1. 1 hit.
PRINTS	PR00105. C5METTRFRASE.
SMART	SM00439. BAH. 2 hits. [Graphical view]
TIGRFAMs	TIGR00675. dcm. 1 hit.
PROSITE	PS51038. BAH. 2 hits. PS00094. C5_MTASE_1. 1 hit. PS00095. C5_MTASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O48866_DAUCA

Accession

Primary (citable) accession number: O48866

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	April 3, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)