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Protein

Vesicle-associated membrane protein 725

Gene

VAMP725

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the targeting and/or fusion of transport vesicles to their target membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle-associated membrane protein 7251 Publication
Short name:
AtVAMP7251 Publication
Gene namesi
Name:VAMP7251 Publication
Ordered Locus Names:At2g32670Imported
ORF Names:F24L7.19Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G32670.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 261261CytoplasmicSequence analysisAdd
BLAST
Transmembranei262 – 28221Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST
Topological domaini283 – 2853VesicularSequence analysis

GO - Cellular componenti

  • early endosome membrane Source: UniProtKB-SubCell
  • endosome Source: TAIR
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: TAIR
  • SNARE complex Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 285285Vesicle-associated membrane protein 725PRO_0000206758Add
BLAST

Proteomic databases

PaxDbiO48850.
PRIDEiO48850.

Expressioni

Tissue specificityi

Expressed in flowers, leaves, stems and roots.1 Publication

Gene expression databases

GenevisibleiO48850. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi3174. 1 interaction.
STRINGi3702.AT2G32670.1.

Structurei

3D structure databases

ProteinModelPortaliO48850.
SMRiO48850. Positions 71-254.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini75 – 179105LonginPROSITE-ProRule annotationAdd
BLAST
Domaini195 – 25561v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated
Contains 1 longin domain.PROSITE-ProRule annotation
Contains 1 v-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiO48850.
KOiK08511.
OMAiVYLCMAD.
OrthoDBiEOG09360NHL.
PhylomeDBiO48850.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O48850-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRSVVPISL APFQFLLVFW IFLTSVHTNP NKQQKTVVSL SLWWNSKNRI
60 70 80 90 100
RGCVWFFFLL RVTRTMGQQN LIYSFVARGT VILVEYTEFK GNFTAVAAQC
110 120 130 140 150
LQKLPSSNNK FTYNCDGHTF NYLVENGFTY CVVAVESVGR QIPMAFLERV
160 170 180 190 200
KEDFNKRYGG GKATTAQANS LNREFGSKLK EHMQYCVDHP DEISKLAKVK
210 220 230 240 250
AQVTEVKGVM MENIEKVLDR GEKIELLVDK TENLRSQAQD FRTQGTKIRR
260 270 280
KMWFENMKIK LIVLGIIITL ILIIILSVCG GFKCT
Length:285
Mass (Da):32,691
Last modified:May 10, 2005 - v2
Checksum:iF8A28595547166EE
GO

Sequence cautioni

The sequence AAC04496 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003974 Genomic DNA. Translation: AAC04496.1. Different initiation.
CP002685 Genomic DNA. Translation: AEC08714.1.
AK118318 mRNA. Translation: BAC42934.1.
BT006042 mRNA. Translation: AAP06822.1.
PIRiT00801.
RefSeqiNP_180826.2. NM_128826.4.
UniGeneiAt.38037.
At.66389.

Genome annotation databases

EnsemblPlantsiAT2G32670.1; AT2G32670.1; AT2G32670.
GeneIDi817827.
GrameneiAT2G32670.1; AT2G32670.1; AT2G32670.
KEGGiath:AT2G32670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003974 Genomic DNA. Translation: AAC04496.1. Different initiation.
CP002685 Genomic DNA. Translation: AEC08714.1.
AK118318 mRNA. Translation: BAC42934.1.
BT006042 mRNA. Translation: AAP06822.1.
PIRiT00801.
RefSeqiNP_180826.2. NM_128826.4.
UniGeneiAt.38037.
At.66389.

3D structure databases

ProteinModelPortaliO48850.
SMRiO48850. Positions 71-254.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi3174. 1 interaction.
STRINGi3702.AT2G32670.1.

Proteomic databases

PaxDbiO48850.
PRIDEiO48850.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G32670.1; AT2G32670.1; AT2G32670.
GeneIDi817827.
GrameneiAT2G32670.1; AT2G32670.1; AT2G32670.
KEGGiath:AT2G32670.

Organism-specific databases

TAIRiAT2G32670.

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiO48850.
KOiK08511.
OMAiVYLCMAD.
OrthoDBiEOG09360NHL.
PhylomeDBiO48850.

Miscellaneous databases

PROiO48850.

Gene expression databases

GenevisibleiO48850. AT.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVA725_ARATH
AccessioniPrimary (citable) accession number: O48850
Secondary accession number(s): Q8GXC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.