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Protein

Receptor like protein 23

Gene

RLP23

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the perception of necrosis and ethylene-inducing peptide 1-like proteins (NLPs), that act as extracellular signals mediating immune activation. Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity.1 Publication

GO - Molecular functioni

  • protein kinase binding Source: UniProtKB

GO - Biological processi

  • defense response signaling pathway, resistance gene-independent Source: UniProtKB
  • defense response to bacterium Source: UniProtKB
  • defense response to fungus Source: UniProtKB
  • defense response to oomycetes Source: UniProtKB
  • detection of molecule of fungal origin Source: UniProtKB
  • response to mannitol Source: UniProtKB
  • response to molecule of bacterial origin Source: UniProtKB
  • response to molecule of fungal origin Source: UniProtKB
  • response to molecule of oomycetes origin Source: UniProtKB

Keywordsi

Molecular functionReceptor
Biological processPlant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Receptor like protein 231 Publication
Short name:
AtRLP231 Publication
Gene namesi
Name:RLP231 Publication
Ordered Locus Names:At2g32680Imported
ORF Names:F24L7.18Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G32680
TAIRilocus:2046357 AT2G32680

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini23 – 850ExtracellularSequence analysisAdd BLAST828
Transmembranei851 – 871HelicalSequence analysisAdd BLAST21
Topological domaini872 – 890CytoplasmicSequence analysisAdd BLAST19

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Impaired in nlp20-mediated immunity.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501194510523 – 890Receptor like protein 23Add BLAST868

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi58N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi70N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi91N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi109N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi145N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi189N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi207N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi242N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi265N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi311N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi351N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi461N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi505N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi518N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi574N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi730N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi778N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiO48849

Expressioni

Inductioni

By mannitol.1 Publication

Gene expression databases

ExpressionAtlasiO48849 differential

Interactioni

Subunit structurei

Directly interacts with a 20-mer fragment (nlp20) from NLPs through its extracellular LRR domain. Component of a trimeric complex composed of RLP23, SOBIR1 and BAK1. BAK1 is recruited into a pre-formed RLP23-SOBIR1 complex in a ligand-dependent manner (PubMed:27251392). Interacts with SOBIR1 (PubMed:24525519, PubMed:27251392).2 Publications

GO - Molecular functioni

  • protein kinase binding Source: UniProtKB

Protein-protein interaction databases

STRINGi3702.AT2G32680.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati97 – 121LRR 1Sequence analysisAdd BLAST25
Repeati123 – 145LRR 2Sequence analysisAdd BLAST23
Repeati146 – 171LRR 3Sequence analysisAdd BLAST26
Repeati173 – 195LRR 4Sequence analysisAdd BLAST23
Repeati196 – 218LRR 5Sequence analysisAdd BLAST23
Repeati220 – 243LRR 6Sequence analysisAdd BLAST24
Repeati244 – 268LRR 7Sequence analysisAdd BLAST25
Repeati270 – 290LRR 8Sequence analysisAdd BLAST21
Repeati291 – 316LRR 9Sequence analysisAdd BLAST26
Repeati318 – 339LRR 10Sequence analysisAdd BLAST22
Repeati340 – 363LRR 11Sequence analysisAdd BLAST24
Repeati364 – 389LRR 12Sequence analysisAdd BLAST26
Repeati391 – 411LRR 13Sequence analysisAdd BLAST21
Repeati412 – 436LRR 14Sequence analysisAdd BLAST25
Repeati438 – 461LRR 15Sequence analysisAdd BLAST24
Repeati462 – 485LRR 16Sequence analysisAdd BLAST24
Repeati487 – 506LRR 17Sequence analysisAdd BLAST20
Repeati507 – 527LRR 18Sequence analysisAdd BLAST21
Repeati528 – 551LRR 19Sequence analysisAdd BLAST24
Repeati553 – 575LRR 20Sequence analysisAdd BLAST23
Repeati577 – 598LRR 21Sequence analysisAdd BLAST22
Repeati599 – 623LRR 22Sequence analysisAdd BLAST25
Repeati626 – 650LRR 23Sequence analysisAdd BLAST25
Repeati699 – 724LRR 24Sequence analysisAdd BLAST26
Repeati726 – 747LRR 25Sequence analysisAdd BLAST22
Repeati748 – 771LRR 26Sequence analysisAdd BLAST24
Repeati773 – 796LRR 27Sequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi831 – 845Glu-richPROSITE-ProRule annotationAdd BLAST15

Sequence similaritiesi

Belongs to the RLP family.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0619 Eukaryota
COG4886 LUCA
HOGENOMiHOG000116562
OMAiPLSICNI
OrthoDBiEOG09360033

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
PfamiView protein in Pfam
PF00560 LRR_1, 2 hits
PF13516 LRR_6, 1 hit
PF13855 LRR_8, 3 hits
SMARTiView protein in SMART
SM00369 LRR_TYP, 10 hits
PROSITEiView protein in PROSITE
PS51450 LRR, 15 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O48849-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKALLHLHF LSLFLLCCVC HSSIFTLNFH FTGIVACRPH QIQAFTKFTN
60 70 80 90 100
EFDTRGCNNS DTFNGVWCDN STGAVAVLQL RKCLSGTLKS NSSLFGFHQL
110 120 130 140 150
RYVDLQNNNL TSSSLPSGFG NLKRLEGLFL SSNGFLGQVP SSFSNLTMLA
160 170 180 190 200
QLDLSYNKLT GSFPLVRGLR KLIVLDLSYN HFSGTLNPNS SLFELHQLRY
210 220 230 240 250
LNLAFNNFSS SLPSKFGNLH RLENLILSSN GFSGQVPSTI SNLTRLTKLY
260 270 280 290 300
LDQNKLTSSF PLVQNLTNLY ELDLSYNKFF GVIPSSLLTL PFLAHLALRE
310 320 330 340 350
NNLAGSVEVS NSSTSSRLEI MYLGSNHFEG QILEPISKLI NLKHLDLSFL
360 370 380 390 400
NTSYPIDLKL FSSLKSLRSL DLSGNSISSA SLSSDSYIPL TLEMLTLRHC
410 420 430 440 450
DINEFPNILK TLKELVYIDI SNNRMKGKIP EWLWSLPLLQ SVTLGNNYFT
460 470 480 490 500
GFQGSAEILV NSSVLLLYLD SNNFEGALPD LPLSIKGFGV ASNSFTSEIP
510 520 530 540 550
LSICNRSSLA AIDLSYNNFT GPIPPCLRNL ELVYLRNNNL EGSIPDALCD
560 570 580 590 600
GASLRTLDVS HNRLTGKLPR SFVNCSSLKF LSVINNRIED TFPFWLKALP
610 620 630 640 650
NLQVLTLRSN RFYGPISPPH QGPLGFPELR IFEISDNKFT GSLPPNYFVN
660 670 680 690 700
WKASSRTMNQ DGGLYMVYEE KLFDEGGYGY TDALDLQYKG LHMEQAKALT
710 720 730 740 750
SYAAIDFSGN RLEGQIPESI GLLKALIAVN ISNNAFTGHI PLSMANLENL
760 770 780 790 800
ESLDMSRNQL SGTIPNGLGS ISFLAYINVS HNQLTGEIPQ GTQITGQSKS
810 820 830 840 850
SFEGNAGLCG LPLKESCFGT GAPPMYHQKQ EDKEEEEEEE EEEEEVLNGR
860 870 880 890
AVAIGYGSGL LLGLAIAQVI ASYKPEWLVK IIGLNKRRKR
Length:890
Mass (Da):98,482
Last modified:June 1, 1998 - v1
Checksum:i297578445B6357EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003974 Genomic DNA Translation: AAC04495.1
CP002685 Genomic DNA Translation: AEC08715.1
PIRiT00800
RefSeqiNP_180827.1, NM_128827.2
UniGeneiAt.66389

Genome annotation databases

EnsemblPlantsiAT2G32680.1; AT2G32680.1; AT2G32680
GeneIDi817828
GrameneiAT2G32680.1; AT2G32680.1; AT2G32680
KEGGiath:AT2G32680

Similar proteinsi

Entry informationi

Entry nameiRLP23_ARATH
AccessioniPrimary (citable) accession number: O48849
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 28, 2018
Last sequence update: June 1, 1998
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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