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Protein

Expansin-A4

Gene

EXPA4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity).By similarity

GO - Biological processi

  • plant-type cell wall organization Source: InterPro
  • syncytium formation Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Cell wall biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Expansin-A4
Short name:
AtEXPA4
Alternative name(s):
Alpha-expansin-4
Short name:
At-EXP4
Short name:
AtEx4
Ath-ExpAlpha-1.6
Gene namesi
Name:EXPA4
Synonyms:EXP4
Ordered Locus Names:At2g39700
ORF Names:F17A14.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G39700.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: TAIR
  • extracellular region Source: UniProtKB-KW
  • membrane Source: UniProtKB-SubCell
  • plant-type cell wall Source: TAIR
  • plasmodesma Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 20201 PublicationAdd
BLAST
Chaini21 – 257237Expansin-A4PRO_0000008685Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi52 ↔ 80PROSITE-ProRule annotation
Disulfide bondi83 ↔ 158PROSITE-ProRule annotation
Disulfide bondi88 ↔ 95PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiO48818.
PRIDEiO48818.

Expressioni

Tissue specificityi

Expressed in the vascular bundles throughout the plant.1 Publication

Gene expression databases

GenevisibleiO48818. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G39700.1.

Structurei

3D structure databases

ProteinModelPortaliO48818.
SMRiO48818. Positions 29-245.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 163115Expansin-like EG45PROSITE-ProRule annotationAdd
BLAST
Domaini173 – 25280Expansin-like CBDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the expansin family. Expansin A subfamily.Curated
Contains 1 expansin-like CBD domain.PROSITE-ProRule annotation
Contains 1 expansin-like EG45 domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IKDM. Eukaryota.
ENOG410YEM2. LUCA.
HOGENOMiHOG000220793.
InParanoidiO48818.
OMAiEIRCVNQ.
OrthoDBiEOG09360L23.
PhylomeDBiO48818.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR002963. Expansin.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01226. EXPANSIN.
PR01225. EXPANSNFAMLY.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O48818-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIKLAILFT TFVLFSLADA RIPGIYSGGA WQNAHATFYG GSDASGTMGG
60 70 80 90 100
ACGYGNLYSQ GYGTNTAALS TALFNNGMSC GACFELKCAN DPQWCHSGSP
110 120 130 140 150
SILITATNFC PPNLAQPSDN GGWCNPPREH FDLAMPVFLK IAQYRAGIVP
160 170 180 190 200
VSYRRVPCRK RGGIRFTING HRYFNLVLIT NVAGAGDIVR ASVKGSRTGW
210 220 230 240 250
MSLSRNWGQN WQSNAVLVGQ ALSFRVTGSD RRTSTSWNMV PSNWQFGQTF

VGKNFRV
Length:257
Mass (Da):27,848
Last modified:June 1, 1998 - v1
Checksum:i5C510E930A35B736
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti155 – 1551R → S in AAM62937 (Ref. 4) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003674 Genomic DNA. Translation: AAB97125.1.
CP002685 Genomic DNA. Translation: AEC09708.1.
AF410277 mRNA. Translation: AAK95263.1.
AY062683 mRNA. Translation: AAL32761.1.
AY093338 mRNA. Translation: AAM13337.1.
AY085719 mRNA. Translation: AAM62937.1.
PIRiD84820.
RefSeqiNP_181500.1. NM_129526.2.
UniGeneiAt.22579.

Genome annotation databases

EnsemblPlantsiAT2G39700.1; AT2G39700.1; AT2G39700.
GeneIDi818553.
GrameneiAT2G39700.1; AT2G39700.1; AT2G39700.
KEGGiath:AT2G39700.

Cross-referencesi

Web resourcesi

EXPANSIN homepage

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003674 Genomic DNA. Translation: AAB97125.1.
CP002685 Genomic DNA. Translation: AEC09708.1.
AF410277 mRNA. Translation: AAK95263.1.
AY062683 mRNA. Translation: AAL32761.1.
AY093338 mRNA. Translation: AAM13337.1.
AY085719 mRNA. Translation: AAM62937.1.
PIRiD84820.
RefSeqiNP_181500.1. NM_129526.2.
UniGeneiAt.22579.

3D structure databases

ProteinModelPortaliO48818.
SMRiO48818. Positions 29-245.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G39700.1.

Proteomic databases

PaxDbiO48818.
PRIDEiO48818.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G39700.1; AT2G39700.1; AT2G39700.
GeneIDi818553.
GrameneiAT2G39700.1; AT2G39700.1; AT2G39700.
KEGGiath:AT2G39700.

Organism-specific databases

TAIRiAT2G39700.

Phylogenomic databases

eggNOGiENOG410IKDM. Eukaryota.
ENOG410YEM2. LUCA.
HOGENOMiHOG000220793.
InParanoidiO48818.
OMAiEIRCVNQ.
OrthoDBiEOG09360L23.
PhylomeDBiO48818.

Miscellaneous databases

PROiO48818.

Gene expression databases

GenevisibleiO48818. AT.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR002963. Expansin.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01226. EXPANSIN.
PR01225. EXPANSNFAMLY.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEXPA4_ARATH
AccessioniPrimary (citable) accession number: O48818
Secondary accession number(s): P80837, Q8LDZ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: June 1, 1998
Last modified: September 7, 2016
This is version 125 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.