Reviewed, UniProtKB/Swiss-Prot O48766 (GUN11_ARATH)

Names and origin

Protein names

Recommended name:
    Endoglucanase 11
    EC=3.2.1.4
Alternative name(s):
    Endo-1,4-beta glucanase 11

Gene names

Ordered Locus Names:	At2g32990
ORF Names:	T21L14.7

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	525 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 9 (cellulase E) family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Cell wall biogenesis/degradation Cellulose degradation Polysaccharide degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW cellulose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cellulase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 31	31	Potential
	Chain	32 – 525	494	Endoglucanase 11		PRO_0000249263
Sites
	Active site	427	1	By similarity
	Active site	479	1	By similarity
	Active site	488	1	By similarity
Amino acid modifications
	Glycosylation	337	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	O48766-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 6E3C3A23165EE44F	FASTA	525	59,087
	10 20 30 40 50 60 MTVMNHRHKQ CHFLLLLLIT VFSAALDGVS SETDVGGFDY GEALSKSLLY FEAQRSGRLP 70 80 90 100 110 120 YNQRVTWRDH SGLTDGLEQG VDLVGGYHDA GDHVKFGLPM AFTVTMLSWS VIEYGDSLAS 130 140 150 160 170 180 TGELSHALEA IKWGTDYFIK AHTSPNVLWA EVGDGDTDHY CWQRPEDMTT SRRAFKIDEN 190 200 210 220 230 240 NPGSDIAGET AAAMAAASIV FRSTNPHYSH LLLHHAQQLF EFGDKYRGKY DESLKVVKSY 250 260 270 280 290 300 YASVSGYMDE LLWGATWLYR ATDNEHYMSY VVDMAHQLGG LSWAMSEFSW DVKFAGVQLL 310 320 330 340 350 360 ASMLLKEEKH KQHSKVLQQY KSKADHYLCS ILNKNINGTN VQRTPAGLLY VRQWNNMQYV 370 380 390 400 410 420 STASFLLTVY SDHLRKSNTD LECHEGTVTP DEMLGFAKSQ IDYILGSNPM ETSYLVGYGP 430 440 450 460 470 480 KYPIRVHHRG ASIASFKEHK GFIGCTQGYD NWYGRSEPNP SVLVGALVGG PDHQDDFDDR 490 500 510 520 RGNYVQTEAC TYNTAPLVGV FARLIELEEQ KLEEEDVSLV ATYKR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed: 10617197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[3]	"Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family." Libertini E., Li Y., McQueen-Mason S.J. J. Mol. Evol. 58:506-515(2004) [PubMed: 15170254] [Abstract] Cited for: GENE FAMILY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC003033 Genomic DNA. Translation: AAB91971.1. AY062439 mRNA. Translation: AAL32517.1. BT008885 mRNA. Translation: AAP68324.1.
IPI	IPI00527694.
PIR	T01108.
RefSeq	NP_180858.1.
UniGene	At.12479
3D structure databases
HSSP	HSSP built from PDB template 1KS8 based on UniProtKB O77044.
ModBase	Search...
Protein family/group databases
CAZy	GH9. Glycoside Hydrolase Family 9.
Genome annotation databases
GeneID	817861.
GenomeReviews	Gene locus AT2G32990 in contig CT485783_GR.
KEGG	ath:AT2G32990.
NMPDR	fig|3702.1.peg.10382.
Organism-specific databases
TAIR	At2g32990.
Phylogenomic databases
OMA	CTQGYDN.
Enzyme and pathway databases
BRENDA	3.2.1.4. 302.
Gene expression databases
ArrayExpress	O48766.
Genevestigator	O48766.
GermOnline	AT2G32990. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR012341. 6hp_glycosidase. IPR001701. Glyco_hydro_9. IPR018221. Glyco_hydro_9_AS. [Graphical view]
Gene3D	G3DSA:1.50.10.10. CelA/Cel48F_cat. 1 hit.
PANTHER	PTHR22298:SF3. Glyco_hydro_9. 1 hit.
Pfam	PF00759. Glyco_hydro_9. 1 hit. [Graphical view]
PROSITE	PS00592. GLYCOSYL_HYDROL_F9_1. 1 hit. PS00698. GLYCOSYL_HYDROL_F9_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GUN11_ARATH

Accession

Primary (citable) accession number: O48766

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	June 1, 1998
Last modified:	November 3, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)