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Protein

Thioredoxin M1, chloroplastic

Gene

At1g03680

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Thiol-disulfide oxidoreductase involved in the redox regulation of enzymes of both reductive pentose phosphate pathway (Calvin-Benson cycle) and oxidative pentose phosphate pathway. Under reducing conditions, activates the glyceraldehyde-3-phosphate dehydrogenase and the phosphoribulokinase, and inhibits. the glucose-6-phosphate dehydrogenase. Activates NADP-malate dehydrogenase.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei98Deprotonates C-terminal active site CysBy similarity1
Active sitei104NucleophileBy similarity1
Sitei105Contributes to redox potential valueBy similarity1
Sitei106Contributes to redox potential valueBy similarity1
Active sitei107NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

  • cell redox homeostasis Source: GO_Central
  • cellular response to oxidative stress Source: GO_Central
  • glycerol ether metabolic process Source: InterPro
  • negative regulation of catalytic activity Source: UniProtKB
  • positive regulation of catalytic activity Source: UniProtKB
  • regulation of carbohydrate metabolic process Source: UniProtKB
  • response to cold Source: TAIR

Keywordsi

Biological processElectron transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin M1, chloroplastic
Short name:
AtTrxm1
Gene namesi
Ordered Locus Names:At1g03680
ORF Names:F21B7.28, F21B7_7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G03680
TAIRilocus:2020813 AT1G03680

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 48ChloroplastSequence analysisAdd BLAST48
ChainiPRO_000003416249 – 179Thioredoxin M1, chloroplasticAdd BLAST131

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi104 ↔ 107Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiO48737
PRIDEiO48737

Expressioni

Gene expression databases

ExpressionAtlasiO48737 baseline and differential
GenevisibleiO48737 AT

Interactioni

Protein-protein interaction databases

BioGridi24671, 3 interactors
IntActiO48737, 1 interactor
STRINGi3702.AT1G03680.1

Structurei

3D structure databases

ProteinModelPortaliO48737
SMRiO48737
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 179ThioredoxinPROSITE-ProRule annotationAdd BLAST113

Sequence similaritiesi

Keywords - Domaini

Redox-active center, Transit peptide

Phylogenomic databases

eggNOGiKOG0910 Eukaryota
COG0526 LUCA
HOGENOMiHOG000292977
InParanoidiO48737
KOiK03671
OMAiVLVEYWA
OrthoDBiEOG09360VDR
PhylomeDBiO48737

Family and domain databases

InterProiView protein in InterPro
IPR005746 Thioredoxin
IPR036249 Thioredoxin-like_sf
IPR017937 Thioredoxin_CS
IPR013766 Thioredoxin_domain
PANTHERiPTHR10438 PTHR10438, 1 hit
PfamiView protein in Pfam
PF00085 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR01068 thioredoxin, 1 hit
PROSITEiView protein in PROSITE
PS00194 THIOREDOXIN_1, 1 hit
PS51352 THIOREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O48737-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYTCTSRP PISIRSEMRI ASSPTGSFST RQMFSVLPES SGLRTRVSLS
60 70 80 90 100
SLSKNSRVSR LRRGVICEAQ DTATGIPVVN DSTWDSLVLK ADEPVFVDFW
110 120 130 140 150
APWCGPCKMI DPIVNELAQK YAGQFKFYKL NTDESPATPG QYGVRSIPTI
160 170
MIFVNGEKKD TIIGAVSKDT LATSINKFL
Length:179
Mass (Da):19,665
Last modified:June 1, 1998 - v1
Checksum:i35B9E7C1D132F492
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF095749 mRNA Translation: AAF15948.1
AC002560 Genomic DNA Translation: AAF86525.1
CP002684 Genomic DNA Translation: AEE27596.1
BT004295 mRNA Translation: AAO42293.1
BT005525 mRNA Translation: AAO63945.1
PIRiT00893
RefSeqiNP_849585.1, NM_179254.7
UniGeneiAt.20253

Genome annotation databases

EnsemblPlantsiAT1G03680.1; AT1G03680.1; AT1G03680
GeneIDi839436
GrameneiAT1G03680.1; AT1G03680.1; AT1G03680
KEGGiath:AT1G03680

Similar proteinsi

Entry informationi

Entry nameiTRXM1_ARATH
AccessioniPrimary (citable) accession number: O48737
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: April 25, 2018
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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