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O48709 (PI5K3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylinositol 4-phosphate 5-kinase 3
Short name=AtPIP5K3
EC=2.7.1.68
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 3
Diphosphoinositide kinase 3
PtdIns(4)P-5-kinase 3
Gene names
Name:PIP5K3
Ordered Locus Names:At2g26420
ORF Names:T9J22.9
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length705 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

Sequence similarities

Contains 7 MORN repeats.

Contains 1 PIPK domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 705705Phosphatidylinositol 4-phosphate 5-kinase 3
PRO_0000185475

Regions

Repeat58 – 8023MORN 1
Repeat81 – 10323MORN 2
Repeat104 – 12623MORN 3
Repeat127 – 14923MORN 4
Repeat150 – 17223MORN 5
Repeat173 – 19523MORN 6
Repeat196 – 21823MORN 7
Domain321 – 701381PIPK
Region661 – 68222Activation loop By similarity

Sequences

Sequence LengthMass (Da)Tools
O48709 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 851E86AE18AAF157

FASTA70580,134
        10         20         30         40         50         60 
MQETVFLFTE ENLNKEQSLG VKYKQSSRRV VPMTSCEVSD TAAEIRIVEK VLKNGDLYNG 

        70         80         90        100        110        120 
GLSAGVPHGT GKYLWSDGCM YEGEWTRGKA SGKGRFSWPS GATYEGQFKD GRMDGEGTFI 

       130        140        150        160        170        180 
GIDGDTYRGH WLWGRKHGYG EKRYANGDGY QGNWKANLQD GNGRYVWSDG NEYVGEWKNG 

       190        200        210        220        230        240 
VISGKGKMTW ANGNRYDGLW ENGAPVGKGV LSWGEEKTSY NGWGRKSKKK DEEIVQNHKL 

       250        260        270        280        290        300 
SSVETLSANT NFPRICISEL EDTGVCDHVE ASPYTSESDT SGCGEQEWAR SPLLLESGGA 

       310        320        330        340        350        360 
MSVQQSPRWL DEGDVKKPGH TVTAGHKNYD LMLNLQLGIR YSVGKHASLL RELRHSDFDP 

       370        380        390        400        410        420 
KDKQWTRFPP EGSKSTPPHL SAEFKWKDYC PIVFRHLRDL FAIDQADYML AICGNESLRE 

       430        440        450        460        470        480 
FASPGKSGSA FYLTQDERYM IKTMKKSEIK VLLKMLPNYY EHVSKYKNSL VTKFFGVHCV 

       490        500        510        520        530        540 
KPVGGQKTRF IVMGNLFCSE YRIHKRFDLK GSSHGRTIDK DEGEIDETTT LKDLDLKYVF 

       550        560        570        580        590        600 
RLETSWFQAF INQIDLDCEF LEAERIMDYS LLIGLHFRES GMRDDISLGI GRRDQEDKLM 

       610        620        630        640        650        660 
RGNGPLMRLG ESTPAKAEQV SRFEEETWEE DAIDNSNPKG TRKEAVEVIL YFGVIDILQD 

       670        680        690        700 
YDITKKLEHA YKSLHADPAS ISAVDPKLYS RRFRDFINKI FIEDK

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
Mueller-Roeber B., Pical C.
Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC002505 Genomic DNA. Translation: AAC14492.1.
CP002685 Genomic DNA. Translation: AEC07835.1.
IPIIPI00528380.
PIRT00975.
RefSeqNP_180210.1. NM_128199.1.
UniGeneAt.38897.

3D structure databases

ProteinModelPortalO48709.
SMRO48709. Positions 379-576.
ModBaseSearch...

Protein-protein interaction databases

STRING3702.AT2G26420.1-P.

Proteomic databases

PRIDEO48709.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G26420.1; AT2G26420.1; AT2G26420.
GeneID817182.
KEGGath:AT2G26420.

Organism-specific databases

TAIRAt2g26420.

Phylogenomic databases

eggNOGCOG4642.
HOGENOMHOG000193875.
InParanoidO48709.
KOK00889.
OMAKYLWSDG.
PhylomeDBO48709.
ProtClustDBCLSN2913019.

Gene expression databases

GenevestigatorO48709.
GermOnlineAT2G26420. Arabidopsis thaliana.

Family and domain databases

InterProIPR003409. MORN.
IPR017163. PIno-4-P-5_kinase_pln.
IPR023610. PInositol-4-P-5-kinase.
IPR002498. PInositol-4-P-5-kinase_core.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view]
PANTHERPTHR23086. PTHR23086. 1 hit.
PfamPF02493. MORN. 7 hits.
PF01504. PIP5K. 1 hit.
[Graphical view]
PIRSFPIRSF037274. PIP5K_plant_prd. 1 hit.
SMARTSM00698. MORN. 7 hits.
SM00330. PIPKc. 1 hit.
[Graphical view]
PROSITEPS51455. PIPK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePI5K3_ARATH
AccessionPrimary (citable) accession number: O48709
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: June 1, 1998
Last modified: May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents