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Protein

Cytochrome c oxidase subunit 2

Gene

cox2

Organism
Brassica campestris (Field mustard)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.UniRule annotation

Cofactori

Cu cationUniRule annotationNote: Binds a copper A center.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotationSAAS annotation, Transport
LigandCopperUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 2UniRule annotation
Gene namesi
Name:cox2Imported
Encoded oniMitochondrionImported
OrganismiBrassica campestris (Field mustard)Imported
Taxonomic identifieri3711 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Transmembranei83 – 105HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500769687917 – 260Cytochrome c oxidase subunit 2Sequence analysisAdd BLAST244

Structurei

3D structure databases

ProteinModelPortaliO48328
SMRiO48328
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 111COX2_TMInterPro annotationAdd BLAST96
Domaini113 – 251COX2_CUAInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the cytochrome c oxidase subunit 2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

CDDicd13912 CcO_II_C, 1 hit
Gene3Di1.10.287.90, 1 hit
2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR002429 CcO_II-like_C
IPR034210 CcO_II_C
IPR008972 Cupredoxin
IPR014222 Cyt_c_oxidase_su2
IPR011759 Cyt_c_oxidase_su2_TM_dom
IPR036257 Cyt_c_oxidase_su2_TM_sf
PfamiView protein in Pfam
PF00116 COX2, 1 hit
PF02790 COX2_TM, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
SSF81464 SSF81464, 1 hit
TIGRFAMsiTIGR02866 CoxB, 1 hit
PROSITEiView protein in PROSITE
PS50857 COX2_CUA, 1 hit
PS50999 COX2_TM, 1 hit

Sequencei

Sequence statusi: Complete.

O48328-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVLKWLFLT ISPCDAAEPW QLGSQDAATP IMQGIIDLHH DIFFFLILIL
60 70 80 90 100
VFVLWILVRA LWHFHYKENA IPQRIVHGTT IEILRTIFPS LISMFIAIPS
110 120 130 140 150
FALLYSMDEV VVDPAITIKA IGHQWYWTYE YSDYNSSDEQ SLTFDSYMIP
160 170 180 190 200
EEDLELGQSR LLEVDNRVVI PAKTHLRIIV TSADVPHSWA VPSSGVKCDA
210 220 230 240 250
VPGRLNQISI LVQREGVYYG QCSEICGTNH AFTPIVVEAV PRKDYGSRVS
260
NQLIPQTGEA
Length:260
Mass (Da):29,431
Last modified:June 1, 1998 - v1
Checksum:iA886C51AFAF50DE1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF036383 Genomic DNA Translation: AAB92366.1
AF037264 Genomic DNA Translation: AAB92666.1

Similar proteinsi

Entry informationi

Entry nameiO48328_BRACM
AccessioniPrimary (citable) accession number: O48328
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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